Special

MmuEX0008599 @ mm9

Exon Skipping

Gene
ENSMUSG00000026405 | C4bp
Description
complement component 4 binding protein [Source:MGI Symbol;Acc:MGI:88229]
Coordinates
chr1:132533278-132539690:-
Coord C1 exon
chr1:132539511-132539690
Coord A exon
chr1:132535646-132535810
Coord C2 exon
chr1:132533278-132533453
Length
165 bp
Sequences
Splice sites
3' ss Seq
TCCCTTGTTTCATCATCAAGACT
3' ss Score
2.97
5' ss Seq
AAGGTAATG
5' ss Score
8.99
Exon sequences
Seq C1 exon
AGATCATCTGTTCTCAGCCAAATATTTTACATGGTGTAATTGTTTCTGGATATAAAGCTACCTATACACACAGAGACTCTGTTAGATTGGCCTGCCTGAATGGGACTGTCCTCAGAGGCAGACATGTCATCGAGTGTCAAGGTAATGGCAATTGGAGTTCTCTCCCGACTTGTGAGTTCG
Seq A exon
ACTGTGATTTACCGCCTGCCATTGTCAATGGATATTATACTAGTATGGTCTACTCTAAGATAACTCTGGTTACATATGAATGTGATAAAGGATACAGACTGGTTGGAAAGGCAATCATCTCCTGCAGCTTTTCAAAGTGGAAAGGGACAGCTCCACAGTGTAAAG
Seq C2 exon
CTCTATGTCAGAAACCAGAGGTAGGAAATGGAACGCTGTCTGATGAGAAAGATCAGTATGTTGAGTCTGAAAATGTCACCATCCAATGTGACTCTGGCTTTGCCATGCTGGGTTCCCAAAGCATCAGTTGTTCAGAGAGTGGAACCTGGTATCCAGAGGTGCCCAGATGTGAGCAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSMUSG00000026405_MULTIEX1-2/3=1-3
Average complexity
S
Mappability confidence:
100%=100=100%
Protein Impact





	

	
Alternative protein isoforms (Ref)





No structure available

		

			
Features


			

				
Disorder rate (Iupred):
  C1=0.000 A=0.000 C2=0.061
 
                        

				
Domain overlap (PFAM):

					





						

							
C1:
PF0008415=Sushi=WD(100=90.2)

							
A:
PF0008415=Sushi=PD(0.1=0.0),PF0008415=Sushi=WD(100=96.4)

							
C2:
PF0008415=Sushi=WD(100=93.2)

						

					

				








    
Main Inclusion Isoform:
ENSMUSP00000027657





     
                   









    
Main Skipping Isoform:
NA





     
      









    
Other Inclusion Isoforms:
ENSMUSP00000130533
          









    
Other Skipping Isoforms:
NA
  



Associated events






Other assemblies


mm10




Conservation


Human
(hg38)
chr1:207141106-207141276 
HIGH PSI
HsaEX6036448
(C4BPA)
Human
(hg19)
chr1:207314451-207314621 
HIGH PSI
HsaEX6036448
(C4BPA)
Rat
(rn6)
chr13:47346697-47346864 
HIGH PSI
RnoEX0015711
(C4bpa)
Cow
(bosTau6)
chr16:4948427-4948597 
Chicken
(galGal4)
No conservation detected
Chicken
(galGal3)
No conservation detected
Zebrafish
(danRer10)
No conservation detected
Fruitfly
(dm6)
chr2R:9228582-9228787 
Fruitfly
(dm6)
chr2R:9229094-9229276 
HIGH PSI
DmeEX0008170
(hig)




Primers PCR

	

		

			
Suggestions for RT-PCR validation

			

				
F: 
TAGATTGGCCTGCCTGAATGG

				
R: 
ACCAGGTTCCACTCTCTGAACA

				
Band lengths: 
248-413

			

		

	





	
Functional annotations
(Submit an annotation)

	


There are 0 annotated functions for this event 


		










GENOMIC CONTEXT[edit]












INCLUSION PATTERN[edit]






SPECIAL DATASETS
  • Pre-implantation embryo development
  • Neural differentiation time course
  • Muscular differentiation time course
  • Spermatogenesis cell types
  • Reprogramming of fibroblasts to iPSCs
  • Hematopoietic precursors and cell types






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