MmuEX0011674 @ mm10
Exon Skipping
Gene
NA
Description
NA
Coordinates
chr6:129467517-129470997:-
Coord C1 exon
chr6:129470899-129470997
Coord A exon
chr6:129468869-129469003
Coord C2 exon
chr6:129467517-129467668
Length
135 bp
Sequences
Splice sites
3' ss Seq
GCTGTTCGTGACGTATGAAGCAT
3' ss Score
1.63
5' ss Seq
CAGGCAAGG
5' ss Score
3.33
Exon sequences
Seq C1 exon
GAAGCCAGGCTCCATCTTCACCTTGGAGGCCCATTGCAGTGGGTTTAGGAATCCTGTGCTTTGTGGTAGTAGTGGTTGCTGCAGTGCTGGGTGCCCTAG
Seq A exon
CATTTTGGTGACACAATTCAGGGAGAAATCCAGAGGAGAAAGACAACTTCCTATCAAGAAATAAAGAGAACCACAAGCCCACAGAATCATCTTTAGATGAGAAGGTGGCTCCCTCCAAGGCATCCCAAACTACAG
Seq C2 exon
GAGGTTTTTCTCAGCCTTGCCTTCCTAATTGGATCATGCATGGGAAGAGCTGTTACCTATTTAGCTTCTCAGGAAATTCCTGGTATGGAAGTAAGAGACACTGCTCCCAGCTAGGTGCTCATCTACTGAAGATAGACAACTCAAAAGAATTT
VastDB Features
Vast-tools module Information
Secondary ID
ENSMUSG00000079293_MULTIEX1-2/3=1-3
Average complexity
S*
Mappability confidence:
100%=100=100%
Protein Impact
NA
Show structural model
Features
Disorder rate (Iupred):
C1=NA A=NA C2=NA
Domain overlap (PFAM):
C1:
NA
A:
NA
C2:
NA
Main Inclusion Isoform:
NA
Main Skipping Isoform:
NA
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Chicken
(galGal4)
No conservation detected
Chicken
(galGal3)
No conservation detected
Zebrafish
(danRer10)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
GAAGCCAGGCTCCATCTTCAC
R:
TGAGTTGTCTATCTTCAGTAGATGAG
Band lengths:
242-377
Functional annotations
There are 2 annotated functions for this event
PMID: 16622020
This event
Overexpression of dectin1-1B results in significantly lower zymosan association compared to the overexpression of dectin-1A at 4?C, 25?C, and 30?C but similar zymosan association at 37?C.
PMID: 11567029
[Negative results]. The two major isoforms differ by the presence of a stalk region separating the carbohydrate recognition domain from the transmembrane region and are the only isoforms that are functional for beta-glucan binding.
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Pre-implantation embryo development
- Ribosome-engaged transcriptomes of neuronal types
- Neural differentiation time course
- Muscular differentiation time course
- Spermatogenesis cell types
- Reprogramming of fibroblasts to iPSCs
- Hematopoietic precursors and cell types