Special

MmuEX0013339 @ mm9

Exon Skipping

Gene
ENSMUSG00000057138 | Cyp2d12
Description
cytochrome P450, family 2, subfamily d, polypeptide 12 [Source:MGI Symbol;Acc:MGI:88604]
Coordinates
chr15:82386631-82387466:+
Coord C1 exon
chr15:82386631-82386802
Coord A exon
chr15:82387074-82387226
Coord C2 exon
chr15:82387306-82387466
Length
153 bp
Sequences
Splice sites
3' ss Seq
ACACACAGATGTGTCTGCAGGTA
3' ss Score
4.62
5' ss Seq
CTGGTGGGT
5' ss Score
6.29
Exon sequences
Seq C1 exon
CTTCAAAACCGCTATGGTGACGTGTTTAGCCTACAGATGGCCTGGAAGCCTATGGTTGTGATCAACAGAATGAAGGCAATGAAGGAAGTGCTGTTGACCTGTGGAGAGGACACTGCTGACCGCCCTCCAGTGCCCATCTTTGAGCATCTTGGTTTCAAGCCCAGATCCCAAG
Seq A exon
GTATGATCTTTGCACCCTATGGACCTGAGTGGCGAGAGCAGAGGCGATTCTCTTTGTCTTCTCTGCGCAATTTTGGCCTGGGCAGGAAATCTCTGGAGGAGTGGGTGATCAAGGAGGCCGGCCACCTCTGTGATGCCTTCACTACTCAGGCTG
Seq C2 exon
GGCAGTACATCAATCCCAACACCATGCTGAAAAAAGCTACGTGCAATGTGATTGCATCTCTCATTTTTGCCCGTCGCTTTGAATATGAAGACCCTTACCTCATCAGGATGCTGAAAGTACTGGAAGATAGTTTGACAGAACTCTCTGGATTAATTCCTGAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSMUSG00000057138_CASSETTE1
Average complexity
S
Mappability confidence:
100%=100=100%
Protein Impact





	

	
Alternative protein isoforms (Ref)





No structure available

		

			
Features


			

				
Disorder rate (Iupred):
  C1=0.000 A=0.000 C2=0.000
 
                        

				
Domain overlap (PFAM):

					





						

							
C1:
PF0006717=p450=FE(67.1=100),PF0006717=p450=PU(1.8=10.3)

							
A:
PF0006717=p450=FE(11.1=100)

							
C2:
PF0006717=p450=PD(0.1=0.0),PF0006717=p450=FE(16.0=100)

						

					

				








    
Main Inclusion Isoform:
ENSMUSP00000071064





     
                   









    
Main Skipping Isoform:
ENSMUSP00000014525





     
      









    
Other Inclusion Isoforms:
NA
          









    
Other Skipping Isoforms:
NA
  



Associated events






Other assemblies


mm10




Conservation


Human
(hg38)
No conservation detected
Human
(hg19)
chr22:42548338-42548490 
Rat
(rn6)
No conservation detected
Cow
(bosTau6)
chr5:113623996-113624148 
Chicken
(galGal4)
chr1:49267478-49267630 
HIGH PSI
GgaEX0017895
(CYP2D6)
Chicken
(galGal3)
chr8:27460606-27460755 
Zebrafish
(danRer10)
chr20:25620388-25620540 
HIGH PSI
DreEX6045073
(cyp2n13)
Fruitfly
(dm6)
No conservation detected




Primers PCR

	

		

			
Suggestions for RT-PCR validation

			

				
F: 
GCCTGGAAGCCTATGGTTGTG

				
R: 
AGCATCCTGATGAGGTAAGGGT

				
Band lengths: 
245-398

			

		

	





	
Functional annotations
(Submit an annotation)

	


There are 0 annotated functions for this event 


		










GENOMIC CONTEXT[edit]












INCLUSION PATTERN[edit]






SPECIAL DATASETS
  • Pre-implantation embryo development
  • Neural differentiation time course
  • Muscular differentiation time course
  • Spermatogenesis cell types
  • Reprogramming of fibroblasts to iPSCs
  • Hematopoietic precursors and cell types






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