Special

MmuEX0013396 @ mm9

Exon Skipping

Gene
ENSMUSG00000073424 | Cyp4f15
Description
cytochrome P450, family 4, subfamily f, polypeptide 15 [Source:MGI Symbol;Acc:MGI:2146921]
Coordinates
chr17:32823004-32836942:+
Coord C1 exon
chr17:32823004-32823202
Coord A exon
chr17:32827589-32827733
Coord C2 exon
chr17:32836876-32836942
Length
145 bp
Sequences
Splice sites
3' ss Seq
GGTTCCTCTCTTGCTTGCAGATC
3' ss Score
10.01
5' ss Seq
CAGGTACTT
5' ss Score
8.17
Exon sequences
Seq C1 exon
GATGCCACAGTTGGACCTGTCTTGGCTGGGACTGAGGCTGGAGGCATCCTCACCATGGCTGCTTTTGCTGCTGATCGGAGCTTCCTGGCTCTTGGCCCGTGTCCTGACTCAGACCTATATCTTCTACAGAACATATCATCATCTTTGTGATTTCCCTCAACCCCCCAAATGGAATTGGTTCTTGGGTCACCTAGGCATG
Seq A exon
ATCACACCCACTGAGCATGGTCTGAAGGAGGTGACTAACCTGGTGGCCACCTACCCCCAGGGCTTCATGACATGGCTGGGTCCTATCATTCCTATCATCACTCTGTGCCACCCTGACATCATTCGATCTGTTCTCAATGCCTCAG
Seq C2 exon
GATGAAGATGGAAAGGAGCTGTCAGATGAGGACATTAGAGCAGAGGCTGACACCTTCATGTTTGAGG
VastDB Features
Vast-tools module Information
Secondary ID
ENSMUSG00000073424_MULTIEX1-1/5=C1-C2
Average complexity
C2
Mappability confidence:
100%=100=100%
Protein Impact





	

	
ORF disruption upon sequence exclusion





No structure available

		

			
Features


			

				
Disorder rate (Iupred):
  C1=0.000 A=0.000 C2=0.043
 
                        

				
Domain overlap (PFAM):

					





						

							
C1:
PF0006717=p450=PU(3.0=20.9)

							
A:
PF0006717=p450=FE(10.3=100)

							
C2:
PF0006717=p450=FE(4.7=100)

						

					

				








    
Main Inclusion Isoform:
ENSMUSP00000129264





     
                   









    
Main Skipping Isoform:
NA





     
      









    
Other Inclusion Isoforms:
ENSMUSP00000008801
          









    
Other Skipping Isoforms:
NA
  



Associated events







Other assemblies


mm10




Conservation


Human
(hg38)
chr19:15678261-15678405 
HsaEX6093633
(CYP4F12)
Human
(hg19)
chr19:15789071-15789215 
HIGH PSI
HsaEX6093633
(CYP4F12)
Rat
(rn6)
No conservation detected
Cow
(bosTau6)
chr7:8553012-8553156 
HIGH PSI
BtaEX6037212
([1])
Chicken
(galGal4)
No conservation detected
Chicken
(galGal3)
No conservation detected
Zebrafish
(danRer10)
chr12:48581621-48581765 
HIGH PSI
DreEX0025514
(cyp4f3)
Fruitfly
(dm6)
No conservation detected




Primers PCR

	

		

			
Suggestions for RT-PCR validation

			

				
F: 
CAGTTGGACCTGTCTTGGCTG

				
R: 
CATGAAGGTGTCAGCCTCTGC

				
Band lengths: 
252-397

			

		

	





	
Functional annotations
(Submit an annotation)

	


There are 0 annotated functions for this event 


		










GENOMIC CONTEXT[edit]












INCLUSION PATTERN[edit]






SPECIAL DATASETS
  • Pre-implantation embryo development
  • Neural differentiation time course
  • Muscular differentiation time course
  • Spermatogenesis cell types
  • Reprogramming of fibroblasts to iPSCs
  • Hematopoietic precursors and cell types






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