Special

MmuEX0015004 @ mm9

Exon Skipping

Gene
ENSMUSG00000022262 | Dnahc5
Description
dynein, axonemal, heavy chain 5 [Source:MGI Symbol;Acc:MGI:107718]
Coordinates
chr15:28378905-28383168:+
Coord C1 exon
chr15:28378905-28379108
Coord A exon
chr15:28381073-28381288
Coord C2 exon
chr15:28382956-28383168
Length
216 bp
Sequences
Splice sites
3' ss Seq
TTGTTGTTGTTGTTGTTCAGAGC
3' ss Score
7.26
5' ss Seq
GAAGTGAGT
5' ss Score
7.97
Exon sequences
Seq C1 exon
GGTGTATCCTGGACCACTGTCCGCTACATGATAGGAGAGATTCAGTATGGAGGCAGAGTCACTGATGACTACGATAAGAGGTTGCTGAACACATTTGCAAAGGTTTGGTTCAGTGAAAACATGTTTGGACCAGATTTCACCTTTTACCAAGGATACAACATTCCAAAATGCAGTACAGTGGATGGCTATCTTCAGTACATCCAG
Seq A exon
AGCTTGCCTGCCTATGACAGCCCAGAGGTGTTTGGGCTCCACCCCAATGCTGACATTACTTACCAGAGCAAGCTGGCCAAGGATGTGCTGGACACTATCCTGGGCATCCAGCCCAAGGACAGCTCCGGTGGAGGGGACGAGACACGGGAGGCTGTGGTGGCCCGCCTGGCTGATGATATGCTAGAGAAGCTTCCAGAAGATTATAGTCCTTTTGAA
Seq C2 exon
GTGAAGGAGAGATTGCAGAAGATGGGACCATTCCAGCCCATGAACATTTTCCTCAGGCAGGAGATTGACAGGATGCAGAGGGTACTCAGCCTTGTCCGTAGCACCCTGACTGAGCTGAAACTAGCTGTTGATGGCACCATTATCATGAGTGAAAATCTAAGAGATGCTCTGGATTGCATGTTTGATGCCAGAATCCCTGCTCGGTGGAAAAAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSMUSG00000022262-'73-74,'73-73,74-74
Average complexity
S
Mappability confidence:
100%=100=100%
Protein Impact





	

	
Alternative protein isoforms (Ref)





No structure available

		

			
Features


			

				
Disorder rate (Iupred):
  C1=0.000 A=0.097 C2=0.000
 
                        

				
Domain overlap (PFAM):

					





						

							
C1:
PF0302810=Dynein_heavy=FE(9.6=100)

							
A:
PF0302810=Dynein_heavy=FE(10.2=100)

							
C2:
PF0302810=Dynein_heavy=FE(10.1=100)

						

					

				








    
Main Inclusion Isoform:
ENSMUSP00000069751





     
                   









    
Main Skipping Isoform:
NA





     
      









    
Other Inclusion Isoforms:
NA
          









    
Other Skipping Isoforms:
NA
  



Associated events






Other assemblies


mm10




Conservation


Human
(hg38)
chr5:13714405-13714620 
ALTERNATIVE
HsaEX0020195
(DNAH5)
Human
(hg19)
chr5:13714514-13714729 
ALTERNATIVE
HsaEX0020195
(DNAH5)
Rat
(rn6)
chr2:81315020-81315235 
Cow
(bosTau6)
chr20:59536304-59536519 
HIGH PSI
BtaEX0011608
(DNAH5)
Chicken
(galGal4)
chr2:76699730-76699945 
HIGH PSI
GgaEX6020553
(DNAH5)
Chicken
(galGal3)
chr2:78609541-78609756 
HIGH PSI
GgaEX6020553
(DNAH5)
Zebrafish
(danRer10)
chr16:9359754-9359969 
HIGH PSI
DreEX6039484
(dnah5)
Fruitfly
(dm6)
No conservation detected




Primers PCR

	

		

			
Suggestions for RT-PCR validation

			

				
F: 
GACCACTGTCCGCTACATGAT

				
R: 
TGCTACGGACAAGGCTGAGTA

				
Band lengths: 
296-512

			

		

	





	
Functional annotations
(Submit an annotation)

	


There are 0 annotated functions for this event 


		










GENOMIC CONTEXT[edit]












INCLUSION PATTERN[edit]






SPECIAL DATASETS
  • Pre-implantation embryo development
  • Neural differentiation time course
  • Muscular differentiation time course
  • Spermatogenesis cell types
  • Reprogramming of fibroblasts to iPSCs
  • Hematopoietic precursors and cell types






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