Special

MmuEX0015025 @ mm9

Exon Skipping

Gene
ENSMUSG00000041144 | Dnahc7c
Description
dynein, axonemal, heavy chain 7B [Source:MGI Symbol;Acc:MGI:2684953]
Coordinates
chr1:46306618-46325604:+
Coord C1 exon
chr1:46306618-46306803
Coord A exon
chr1:46310215-46310378
Coord C2 exon
chr1:46325450-46325604
Length
164 bp
Sequences
Splice sites
3' ss Seq
TTTCTGTGAATATTTTGAAGAAT
3' ss Score
4.69
5' ss Seq
AATGTAAGG
5' ss Score
6.17
Exon sequences
Seq C1 exon
GTTGACTTGTGCAGCAAAAAGCTAGAACGCGCAGAGCAGCTGATCGGGGGCCTGGGAGGTGAGAAAACCCGATGGAGCAACTCCGCGCTGGAGCTTGGGCATCTGTACATCAACCTGACGGGAGATATCCTCATCTCCTCAGGGGTTGTCGCCTACCTGGGAGCCTTTACATCTAACTACAGACAG
Seq A exon
AATCAAACCCAGGAGTGGTCACAGTCGTGTAAAGAAAGAGACATCCCCTGCTCTGATGACTACTCTCTTATGGGCACACTGGGAGAGGCCGTGACGATTCGAGCTTGGAATATCGCTGGGTTACCCTCTGACTCTTTCTCCATTGATAATGGGATCATTATAAT
Seq C2 exon
GAATGCAAGAAGGTGGCCTCTGATGATAGACCCTCAAGGTCAGGCTAATAAGTGGATCAAGAACATGGAGAAAACCAATAGCCTTCAGCTCATTAAACTAAGTGACCCTGACTATGTCAGAACTCTGGAAAACTGTATCCAGTTTGGAACTCCTG
VastDB Features
Vast-tools module Information
Secondary ID
ENSMUSG00000041144-'50-47,'50-46,51-47
Average complexity
S
Mappability confidence:
100%=100=100%
Protein Impact





	

	
ORF disruption upon sequence exclusion





No structure available

		

			
Features


			

				
Disorder rate (Iupred):
  C1=0.000 A=0.055 C2=0.000
 
                        

				
Domain overlap (PFAM):

					





						

							
C1:
PF127772=MT=PD(19.7=59.0),PF127812=AAA_9=PU(12.6=24.8)

							
A:
PF127772=MT=PD(2.0=12.7),PF127812=AAA_9=PU(12.6=52.7)

							
C2:
PF127812=AAA_9=FE(22.5=100)

						

					

				








    
Main Inclusion Isoform:
ENSMUSP00000068738





     
                   









    
Main Skipping Isoform:
NA





     
      









    
Other Inclusion Isoforms:
ENSMUSP00000068738f4197A, ENSMUSP00000068738f4198A, ENSMUSP00000068738f5803A, ENSMUSP00000068738f5806A, ENSMUSP00000068738f5807A
          









    
Other Skipping Isoforms:
NA
  



Associated events






Conservation


Human
(hg38)
chr2:195845002-195845165 
ALTERNATIVE
HsaEX0020204
(DNAH7)
Human
(hg19)
chr2:196709726-196709889 
ALTERNATIVE
HsaEX0020204
(DNAH7)
Rat
(rn6)
chr9:60177864-60178027 
Cow
(bosTau6)
chr2:84848809-84848972 
ALTERNATIVE
BtaEX0011615
(DNAH7)
Chicken
(galGal4)
chr7:9208339-9208502 
HIGH PSI
GgaEX6041828
(DNAH7)
Chicken
(galGal3)
chr7:10697671-10697834 
HIGH PSI
GgaEX6041828
(DNAH7)
Zebrafish
(danRer10)
chr9:25174267-25174430 
HIGH PSI
DreEX6036422
(dnah7)
Fruitfly
(dm6)
No conservation detected




Primers PCR

	

		

			
Suggestions for RT-PCR validation

			

				
F: 
AAAGCTAGAACGCGCAGAGC

				
R: 
GCTGAAGGCTATTGGTTTTCTCC

				
Band lengths: 
258-422

			

		

	





	
Functional annotations
(Submit an annotation)

	


There are 0 annotated functions for this event 


		










GENOMIC CONTEXT[edit]












INCLUSION PATTERN[edit]






SPECIAL DATASETS
  • Pre-implantation embryo development
  • Neural differentiation time course
  • Muscular differentiation time course
  • Spermatogenesis cell types
  • Reprogramming of fibroblasts to iPSCs
  • Hematopoietic precursors and cell types






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