Special

MmuEX0015035 @ mm9

Exon Skipping

Gene
ENSMUSG00000041144 | Dnahc7c
Description
dynein, axonemal, heavy chain 7B [Source:MGI Symbol;Acc:MGI:2684953]
Coordinates
chr1:46400579-46409890:+
Coord C1 exon
chr1:46400579-46400716
Coord A exon
chr1:46401628-46401707
Coord C2 exon
chr1:46409660-46409890
Length
80 bp
Sequences
Splice sites
3' ss Seq
TTTTTGTAATGTTTTGGTAGCAA
3' ss Score
3.01
5' ss Seq
CAGGTAAAG
5' ss Score
9.65
Exon sequences
Seq C1 exon
CACAAAAGCTACATCAACTACACAAAGACTTTGCCACTGATCCCAGCACCAGAAGTCTTTGGGATGAATGCCAATGCCGACATCACTAAGGACCAGTCGGAGACGCAGCTGCTGTTTGATAACATTCTCCTTACCCAG
Seq A exon
CAAATTAATCTAGATGCCACGAGTTCCCATGGAGGTTAAATAAACTAAGGACACCTAACTGTTCAGTCTGGAAGATGCAG
Seq C2 exon
TCTCAGTCATCAGGTTCTGGAACAAAGTCATCAGATGAAGTAGTAAATGAGGTTGCTGGAGATATCCTGAGTAAACTTCCAAACAACTTTGATGTTGAAGCTGCCATGAGGAGATACCCAACAACTTACACTCAGAGCATGAACACTGTCCTTGTCCAAGAGATGGGACGTTTCAATAAGTTGCTGATAACCATAAGAGAATCATGCATTAATATTCAAAAAGCAATCAAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSMUSG00000041144-'67-64,'67-63,68-64
Average complexity
S
Mappability confidence:
100%=100=100%
Protein Impact





	

	
ORF disruption upon sequence inclusion





No structure available

		

			
Features


			

				
Disorder rate (Iupred):
  C1=0.043 A=0.167 C2=0.091
 
                        

				
Domain overlap (PFAM):

					





						

							
C1:
PF0302810=Dynein_heavy=FE(10.4=100)

							
A:
PF0302810=Dynein_heavy=PD(2.3=76.9)

							
C2:
PF0302810=Dynein_heavy=FE(10.7=100)

						

					

				








    
Main Inclusion Isoform:
ENSMUSP00000068738f4198A





     
                   









    
Main Skipping Isoform:
ENSMUSP00000068738





     
      









    
Other Inclusion Isoforms:
NA
          









    
Other Skipping Isoforms:
ENSMUSP00000068738f5803A, ENSMUSP00000068738f5806A, ENSMUSP00000092571
  



Associated events







Other assemblies


mm10




Conservation


Human
(hg38)
No conservation detected
Human
(hg19)
chr2:196639545-196639674 
Rat
(rn6)
No conservation detected
Cow
(bosTau6)
chr2:84788623-84788756 
Chicken
(galGal4)
No conservation detected
Chicken
(galGal3)
No conservation detected
Zebrafish
(danRer10)
No conservation detected
Fruitfly
(dm6)
No conservation detected




Primers PCR

	

		

			
Suggestions for RT-PCR validation

			

				
F: 
TGCCGACATCACTAAGGACCA

				
R: 
GGGTATCTCCTCATGGCAGCT

				
Band lengths: 
183-263

			

		

	





	
Functional annotations
(Submit an annotation)

	


There are 0 annotated functions for this event 


		










GENOMIC CONTEXT[edit]












INCLUSION PATTERN[edit]






SPECIAL DATASETS
  • Pre-implantation embryo development
  • Neural differentiation time course
  • Muscular differentiation time course
  • Spermatogenesis cell types
  • Reprogramming of fibroblasts to iPSCs
  • Hematopoietic precursors and cell types






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