MmuEX0015729 @ mm9
Exon Skipping
Gene
ENSMUSG00000069441 | Dsg1a
Description
desmoglein 1 alpha [Source:MGI Symbol;Acc:MGI:94930]
Coordinates
chr18:20489956-20492310:+
Coord C1 exon
chr18:20489956-20490215
Coord A exon
chr18:20490520-20490659
Coord C2 exon
chr18:20491981-20492310
Length
140 bp
Sequences
Splice sites
3' ss Seq
ATTATTTCTTTTAAATACAGATA
3' ss Score
5.96
5' ss Seq
ATGGTAAGA
5' ss Score
9.48
Exon sequences
Seq C1 exon
CCCCTAGATTATGAAGCCATGAAGAATCTACAGCTTAGTATTGGTGTTCGGAATGTAGCTGAATTCCACCAGTCAATTATTTCTCAATACAGACTCACAGCAACTATGGTCACTGTGACTGTGTTAAATGTCATCGAGGGCTCTGTGTTCCGTCCAGGTTCAAAGACATTTGTAGTAGACAGTAGAATGGAAGCAAATCACAGAGTGGGAGAGTTTGTAGCTACAGACCTGGACACAGGTCGAGCTTCCACAAATGTTAG
Seq A exon
ATATGAAATGGGAAATAACCCAGAGAACCTGCTGGTTGTTGACTCAAGAACAGGCATAATAACGTTAAGAAACAGAGTTACTATGGAACAATACCAAAGGCTTAATGGGGAATATAAAGGAACAGTGCTATCAATAGATG
Seq C2 exon
ATTCCCTTCAGAGGACCTGCACGGGGACAATCGTCATTGAACTTAGTGGCACTGGCTGGGTAACTGGTTCAGAAAGTGGTGGCAGTTCCAGTGGCAGTGGCGATGATCGTGACCGAGTGACTAATGGATATCAAGGCACTTCTTCCACTGAGAACCCACAACGCGTCACAGGATCATGGGGAGGCAGCGGCATCGATGGCACTCGCCCTAACACTAACCCTTTCCAAGGGGATCCTGATGAAACCCTTGAGACCCCTCTCTATGGAGACAACGTTCACTTCGGTCCTGCAGGCATCGGGCTGCTCATCATGGGGTTCCTAGTCTTAGGAT
VastDB Features
Vast-tools module Information
Secondary ID
ENSMUSG00000069441_CASSETTE1
Average complexity
S
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence exclusion
Show structural model
Features
Disorder rate (Iupred):
C1=0.057 A=0.104 C2=0.613
Domain overlap (PFAM):
C1:
PF0002812=Cadherin=PD(39.4=47.1),PF0002812=Cadherin=PU(33.7=36.8)
A:
PF0002812=Cadherin=FE(49.5=100)
C2:
PF0002812=Cadherin=PD(15.8=13.5)
Main Skipping Isoform:
NA
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
NA
Associated events
Conservation
Chicken
(galGal4)
No conservation detected
Zebrafish
(danRer10)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
CACAGGTCGAGCTTCCACAAA
R:
GGTTAGTGTTAGGGCGAGTGC
Band lengths:
246-386
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Pre-implantation embryo development
- Neural differentiation time course
- Muscular differentiation time course
- Spermatogenesis cell types
- Reprogramming of fibroblasts to iPSCs
- Hematopoietic precursors and cell types