MmuEX0017724 @ mm10
Exon Skipping
Gene
ENSMUSG00000027249 | F2
Description
coagulation factor II [Source:MGI Symbol;Acc:MGI:88380]
Coordinates
chr2:91629151-91630266:-
Coord C1 exon
chr2:91630153-91630266
Coord A exon
chr2:91629950-91630076
Coord C2 exon
chr2:91629151-91629318
Length
127 bp
Sequences
Splice sites
3' ss Seq
CCGTCTGTCTTGCTCTGCAGACT
3' ss Score
11.21
5' ss Seq
CTGGTGCGT
5' ss Score
8.29
Exon sequences
Seq C1 exon
AGGAGGCGGTGGGAGAGGAGAACTATGATGTGGACGAGTCCATCGCGGGACGCACCACCGATGCGGAGTTCCACACCTTCTTCAATGAGAAGACCTTCGGCCTTGGGGAGGCAG
Seq A exon
ACTGTGGCCTGCGGCCTTTGTTCGAGAAGAAGTCGTTGAAAGACACAACCGAAAAGGAGCTTCTTGACTCTTACATAGACGGGCGCATCGTGGAGGGCTGGGACGCTGAGAAGGGTATCGCCCCCTG
Seq C2 exon
GCAGGTGATGCTTTTTCGGAAGAGTCCCCAAGAGCTGCTGTGTGGGGCCAGCCTTATCAGTGACCGATGGGTCCTCACTGCTGCCCACTGCATTCTGTACCCACCCTGGGACAAGAACTTCACTGAGAATGACCTCCTGGTGCGCATTGGCAAGCATTCCCGAACCAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSMUSG00000027249-'16-18,'16-16,18-18
Average complexity
S
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence exclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.026 A=0.000 C2=0.000
Domain overlap (PFAM):
C1:
PF093965=Thrombin_light=PU(40.8=51.3)
A:
PF093965=Thrombin_light=PD(57.1=65.1),PF0008921=Trypsin=PU(5.2=30.2)
C2:
PF0008921=Trypsin=FE(22.4=100)
Main Skipping Isoform:
NA
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
GCGGTGGGAGAGGAGAACTAT
R:
CCAGGAGGTCATTCTCAGTGA
Band lengths:
249-376
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Pre-implantation embryo development
- Ribosome-engaged transcriptomes of neuronal types
- Neural differentiation time course
- Muscular differentiation time course
- Spermatogenesis cell types
- Reprogramming of fibroblasts to iPSCs
- Hematopoietic precursors and cell types