MmuEX0024686 @ mm10
Exon Skipping
Gene
ENSMUSG00000001281 | Itgb7
Description
integrin beta 7 [Source:MGI Symbol;Acc:MGI:96616]
Coordinates
chr15:102215995-102217097:-
Coord C1 exon
chr15:102216892-102217097
Coord A exon
chr15:102216472-102216630
Coord C2 exon
chr15:102215995-102216267
Length
159 bp
Sequences
Splice sites
3' ss Seq
AAACCTTGGCCCCACCAGAGGGA
3' ss Score
-10.93
5' ss Seq
CAGGTGAGG
5' ss Score
10.07
Exon sequences
Seq C1 exon
GGATTGTGCAGAGTGCGGGGCATTTGGTACCGGTCCCCTGGCAGCCAACTGTAGTGTGGTCTGTGCTGACGTGAATGTGACCTTGACCTTGGCCCCTAACTTGGATGATGGCTGGTGCAAAGAAAGGACAATAGACAACCAGCTGTTCTTCTTCCTGGTGGAGCATGCAGCCAGCGGGATCGTACTGAGAGTGAGACCCCAAGAGA
Seq A exon
GGAGTGGATCACACCCGTGCCATCATACTGGGCTGCACAGGGGGCATCGTGGCAGTGGGACTAGGGCTGGTTCTGGCTTACCGGCTCTCTGTGGAAATCTACGACCGACGGGAGTACAGGCGCTTTGAGAAGGAGCAGCAGCAACTCAACTGGAAGCAG
Seq C2 exon
GACAACAATCCTCTCTACAAAAGTGCGATCACAACCACTGTCAACCCCCGCTTCCAAGGGACAAACGGTCGGTCGCCATCCCTCTCTCTGACCAGGGAAGCAGACTGACTTAGGATTCTTGTCTTGGAGGACAGTGGAGATAGAAGGGCAGGGCAGCGTCTGTCAGGCAAAGATGCTGCCACCGCTGAGATTTTTCAGAGTGACCTTCAGAGGGCAGCAGCCATTCCCACCACACGAAGGGCTGGTCCTTCCATAATAAAGCTTTGCCCCAGA
VastDB Features
Vast-tools module Information
Secondary ID
ENSMUSG00000001281_CASSETTE1
Average complexity
S*
Mappability confidence:
100%=100=100%
Protein Impact
Alternative protein isoforms (No Ref)
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=0.019 C2=0.543
Domain overlap (PFAM):
C1:
NO
A:
PF087256=Integrin_b_cyt=PU(53.2=46.3)
C2:
PF087256=Integrin_b_cyt=PD(42.6=55.6)
Main Skipping Isoform:
NA
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
GTAGTGTGGTCTGTGCTGACG
R:
CCTGGTCAGAGAGAGGGATGG
Band lengths:
252-411
Functional annotations
There are 1 annotated functions for this event
PMID: 12606711
Partially encodes an experimentally validated Eukaryotic Linear Motif (ELM). Method: alanine scanning, surface plasmon resonance. ELM ID: ELMI001554; ELM sequence: QDSNPLYK; Overlap: PARTIAL_RIGHT
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Pre-implantation embryo development
- Ribosome-engaged transcriptomes of neuronal types
- Neural differentiation time course
- Muscular differentiation time course
- Spermatogenesis cell types
- Reprogramming of fibroblasts to iPSCs
- Hematopoietic precursors and cell types