Special

MmuEX0025828 @ mm9

Exon Skipping

Gene
ENSMUSG00000030167 | Klrc1
Description
killer cell lectin-like receptor subfamily C, member 1 [Source:MGI Symbol;Acc:MGI:1336161]
Coordinates
chr6:129627165-129628415:-
Coord C1 exon
chr6:129628314-129628415
Coord A exon
chr6:129627783-129627833
Coord C2 exon
chr6:129627165-129627340
Length
51 bp
Sequences
Splice sites
3' ss Seq
AGAATATTTTAACTCTTCAGATA
3' ss Score
6.03
5' ss Seq
GAGGTACAT
5' ss Score
6.75
Exon sequences
Seq C1 exon
GTTTTCCATCTCCTCCAGAGAAACTCATTGCTGGTACCCTGGGCCTCATCTGTTTTGTCTTAATTGTCGCTGTGGTTGTAATTACTACAGTTGCCACACCAT
Seq A exon
ATACCGAAGCAAAGGCACAGATCAATTCCTCAATGACTAGAACCCACAGAG
Seq C2 exon
ATATAAACTACACTCTATCTTCAGCACAGCCTTGTCCTCATTGTCCAAAGGAGTGGATATCATATTCTCACAATTGTTATTTCATTGGTATGGAGAGAAAATCTTGGAATGACAGTTTGGTGTCCTGCATTTCCAAAAACTGTAGTCTGCTTTACATAGATAGTGAAGAGGAGCAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSMUSG00000030167_MULTIEX1-2/2=1-C2
Average complexity
C1
Mappability confidence:
100%=100=100%
Protein Impact





	

	
Alternative protein isoforms (Ref)





No structure available

		

			
Features


			

				
Disorder rate (Iupred):
  C1=0.000 A=0.074 C2=0.000
 
                        

				
Domain overlap (PFAM):

					





						

							
C1:
PF083915=Ly49=PU(53.4=88.6),PF129112=OppC_N=PU(54.5=68.6)

							
A:
PF083915=Ly49=FE(29.3=100),PF129112=OppC_N=FE(38.6=100)

							
C2:
PF083915=Ly49=PD(15.5=15.3),PF129112=OppC_N=PD(4.5=3.4),PF0005916=Lectin_C=PU(28.1=45.8)

						

					

				








    
Main Inclusion Isoform:
ENSMUSP00000032270





     
                   









    
Main Skipping Isoform:
ENSMUSP00000114017





     
      









    
Other Inclusion Isoforms:
ENSMUSP00000032271, ENSMUSP00000130762
          









    
Other Skipping Isoforms:
NA
  



Associated events







Other assemblies


mm10




Conservation


Human
(hg38)
chr12:10449914-10449967 
ALTERNATIVE
HsaEX0034918
(KLRC1)
Human
(hg19)
chr12:10587085-10587135 
Rat
(rn6)
chr4:163462548-163462598 
HIGH PSI
RnoEX6015320
(Klrc1)
Cow
(bosTau6)
chr5:99975611-99975664 
Chicken
(galGal4)
No conservation detected
Chicken
(galGal3)
No conservation detected
Zebrafish
(danRer10)
No conservation detected
Fruitfly
(dm6)
No conservation detected




Primers PCR

	

		

			
Suggestions for RT-PCR validation

			

				
F: 
CCTCCAGAGAAACTCATTGCTGG

				
R: 
ACAATGAGGACAAGGCTGTGC

				
Band lengths: 
135-186

			

		

	





	
Functional annotations
(Submit an annotation)

	


There are 0 annotated functions for this event 


		










GENOMIC CONTEXT[edit]












INCLUSION PATTERN[edit]






SPECIAL DATASETS
  • Pre-implantation embryo development
  • Neural differentiation time course
  • Muscular differentiation time course
  • Spermatogenesis cell types
  • Reprogramming of fibroblasts to iPSCs
  • Hematopoietic precursors and cell types






Retrieved from "https://vastdb.crg.eu/wiki/Special:VastDB"