Special

MmuEX0025969 @ mm9

Exon Skipping

Gene
Description
kynureninase (L-kynurenine hydrolase) [Source:MGI Symbol;Acc:MGI:1918039]
Coordinates
chr2:43487066-43528276:+
Coord C1 exon
chr2:43487066-43487139
Coord A exon
chr2:43526879-43526931
Coord C2 exon
chr2:43528191-43528276
Length
53 bp
Sequences
Splice sites
3' ss Seq
ATTGTTATCTTAAATTTCAGGTT
3' ss Score
9.33
5' ss Seq
ACAGTAAGT
5' ss Score
9.49
Exon sequences
Seq C1 exon
TATTTAAATTCAGGAGCTGGAGGTCTGGCTGGTGCCTTTGTCCACGAGAAACATGCTCATACTGTCAAGCCTGC
Seq A exon
GTTAGTGGGATGGTTCGGCCATGACCTCAGTACAAGGTTTAACATGGATAACA
Seq C2 exon
AACTACAATTAATCCCCGGGGCCAATGGATTCCGAATTTCAAACCCTCCCATTTTGTTGGTCTGCTCCTTGCACGCCAGTTTAGAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSMUSG00000026866-'11-14,'11-13,14-14
Average complexity
S
Mappability confidence:
100%=100=100%
Protein Impact

ORF disruption upon sequence exclusion

No structure available
Features
Disorder rate (Iupred):
  C1=0.000 A=0.000 C2=0.000
Domain overlap (PFAM):

C1:
PF0026614=Aminotran_5=FE(10.1=100)
A:
PF0026614=Aminotran_5=FE(5.4=100)
C2:
PF0026614=Aminotran_5=FE(8.4=100)


Main Inclusion Isoform:


Main Skipping Isoform:


Other Inclusion Isoforms:


Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Chicken
(galGal4)
HIGH PSI
Zebrafish
(danRer10)
HIGH PSI
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
ATTCAGGAGCTGGAGGTCTGG
R:
GGAGCAGACCAACAAAATGGGA
Band lengths:
135-188
Functional annotations
There are 0 annotated functions for this event


GENOMIC CONTEXT[edit]

INCLUSION PATTERN[edit]


SPECIAL DATASETS

  • Pre-implantation embryo development
  • Neural differentiation time course
  • Muscular differentiation time course
  • Spermatogenesis cell types
  • Reprogramming of fibroblasts to iPSCs
  • Hematopoietic precursors and cell types