HsaEX0035098 @ hg19
Exon Skipping
Gene
ENSG00000115919 | KYNU
Description
kynureninase [Source:HGNC Symbol;Acc:6469]
Coordinates
chr2:143743517-143790890:+
Coord C1 exon
chr2:143743517-143743590
Coord A exon
chr2:143787196-143787248
Coord C2 exon
chr2:143790805-143790890
Length
53 bp
Sequences
Splice sites
3' ss Seq
TGTTTTTATTTATATTTTAGATT
3' ss Score
10.23
5' ss Seq
ACAGTAAGT
5' ss Score
9.49
Exon sequences
Seq C1 exon
TATTTAAATGCAGGAGCAGGAGGAATTGCTGGTGCCTTCATTCATGAAAAGCATGCCCATACGATTAAACCTGC
Seq A exon
ATTAGTGGGATGGTTTGGCCATGAACTCAGCACCAGATTTAAGATGGATAACA
Seq C2 exon
AACTGCAGTTAATCCCTGGGGTCTGTGGATTCCGAATTTCAAATCCTCCCATTTTGTTGGTCTGTTCCTTGCATGCTAGTTTAGAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000115919_MULTIEX1-2/3=C1-3
Average complexity
S
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence exclusion
Show PDB structure
Features
Disorder rate (Iupred):
C1=0.000 A=0.000 C2=0.000
Domain overlap (PFAM):
C1:
PF0026614=Aminotran_5=FE(10.2=100)
A:
PF0026614=Aminotran_5=FE(5.3=100)
C2:
PF0026614=Aminotran_5=FE(8.3=100)
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
GAGGAATTGCTGGTGCCTTCA
R:
AGCATGCAAGGAACAGACCAA
Band lengths:
132-185
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- The Cancer Genome Atlas (TCGA)
- Genotype-Tissue Expression Project (GTEx)
- Autistic and control brains
- Pre-implantation embryo development
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)