Special

MmuEX0026673 @ mm9

Exon Skipping

Gene
ENSMUSG00000000693 | Loxl3
Description
lysyl oxidase-like 3 [Source:MGI Symbol;Acc:MGI:1337004]
Coordinates
chr6:82988389-82998201:+
Coord C1 exon
chr6:82988389-82988603
Coord A exon
chr6:82994109-82994165
Coord C2 exon
chr6:82997982-82998201
Length
57 bp
Sequences
Splice sites
3' ss Seq
ATCTTGTCTTATCCTCACAGAAA
3' ss Score
9.12
5' ss Seq
AAGGTAAAG
5' ss Score
9.06
Exon sequences
Seq C1 exon
GTGGAGCATCAGTTGCAAGTGGAGGAGGTGCGACTCCGACCTGCGGTGGAGTGGGGAAGGAGACCCCTGCCTGTGACTGAGGGCCTGGTTGAAGTCAGGCTTCCTGAAGGCTGGTCGCAAGTGTGTGACAAAGGCTGGAGTGCCCACAACAGCCACGTAGTCTGCGGTATGCTGGGCTTCCCCGGAGAAAAGAGAGTCAACATGGCCTTCTACAG
Seq A exon
AAAGTTGAGGAAGCGAGCGGCCAAAGCCTCAGCCCGACACCCCAAGTCCCTTGGAAG
Seq C2 exon
GATGCTGGCCCAGAAGAAGCAACACTCCTTTGGTCTGCACAGTGTGGCATGTGTGGGCACAGAAGCCCACCTCTCCCTTTGCTCTCTAGAGTTCTATCGTGCCAATGACACCACCAGGTGCTCTGGGGGAAACCCTGCAGTGGTGAGCTGTGTGCTGGGCCCTCTTTATGCCACCTTTACTGGTCAGAAGAAGCAGCAACACTCTAAGCCTCAAGGGGAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSMUSG00000000693_CASSETTE2
Average complexity
S
Mappability confidence:
100%=100=100%
Protein Impact





	

	
Alternative protein isoforms (No Ref)





Show structural model

		

			
Features


			

				
Disorder rate (Iupred):
  C1=0.000 A=0.400 C2=0.149
 
                        

				
Domain overlap (PFAM):

					





						

							
C1:
PF0053013=SRCR=PU(48.5=68.1)

							
A:
PF0053013=SRCR=FE(15.8=100)

							
C2:
PF0053013=SRCR=PD(50.5=68.9)

						

					

				








    
Main Inclusion Isoform:
ENSMUSP00000000707f38A





     
                   









    
Main Skipping Isoform:
ENSMUSP00000000707





     
      









    
Other Inclusion Isoforms:
NA
          









    
Other Skipping Isoforms:
ENSMUSP00000098815
  



Associated events






Other assemblies


mm10




Conservation


Human
(hg38)
No conservation detected
Human
(hg19)
chr2:74766920-74766976 
Rat
(rn6)
No conservation detected
Cow
(bosTau6)
chr11:10083411-10084153 
LOW PSI
BtaEX0020397
(LOXL3)
Chicken
(galGal4)
No conservation detected
Chicken
(galGal3)
No conservation detected
Zebrafish
(danRer10)
chr13:15134673-15134723 
ALTERNATIVE
DreEX0043448
(loxl3b)
Zebrafish
(danRer10)
chr13:15145018-15145092 
ALTERNATIVE
DreEX0043447
(loxl3b)
Fruitfly
(dm6)
No conservation detected




Primers PCR

	

		

			
Suggestions for RT-PCR validation

			

				
F: 
GTGTGTGACAAAGGCTGGAGT

				
R: 
GCAGACCAAAGGAGTGTTGCT

				
Band lengths: 
133-190

			

		

	





	
Functional annotations
(Submit an annotation)

	


There are 0 annotated functions for this event 


		










GENOMIC CONTEXT[edit]












INCLUSION PATTERN[edit]






SPECIAL DATASETS
  • Pre-implantation embryo development
  • Neural differentiation time course
  • Muscular differentiation time course
  • Spermatogenesis cell types
  • Reprogramming of fibroblasts to iPSCs
  • Hematopoietic precursors and cell types






Retrieved from "https://vastdb.crg.eu/wiki/Special:VastDB"