MmuEX0026872 @ mm10
Exon Skipping
Gene
ENSMUSG00000027070 | Lrp2
Description
low density lipoprotein receptor-related protein 2 [Source:MGI Symbol;Acc:MGI:95794]
Coordinates
chr2:69499192-69500787:-
Coord C1 exon
chr2:69500610-69500787
Coord A exon
chr2:69500101-69500182
Coord C2 exon
chr2:69499192-69499320
Length
82 bp
Sequences
Splice sites
3' ss Seq
CTCTCCTCAAATCTCTCCAGTGG
3' ss Score
6.82
5' ss Seq
CAGGCGAGT
5' ss Score
2.92
Exon sequences
Seq C1 exon
GTTCTCCACCATCCGCACGCTCTTACTCTGTTTGAAGACTCTGTGTTCTGGACTGACCGCGGCACTCACCAGGTCATGCAGGCCAACAAGTGGCACGGGAGGAACCAATCTGTTGTAATGTACAGCGTTCCCCAACCGCTCGGAATAATTGCCATCCATCCCTCCAGGCAACCATCTT
Seq A exon
TGGTGTCTCACAGTCTGGCCCTGTTTCTTCTGTGGCTTACATTCACCACGCTGGACTACATCATGGTCCAGTGACGCACCAG
Seq C2 exon
CCCCGAATCCATGTGCCTCTGCCACTTGCAGCCATCTTTGCCTGCTTTCTGCACAGGAGCCTAGACATTACTCTTGTGCTTGTCCCTCAGGGTGGAACCTTTCTGATGATTCTGTCAACTGTGTGAGAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSMUSG00000027070_CASSETTE3
Average complexity
S
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.014 A=0.000 C2=0.000
Domain overlap (PFAM):
C1:
PF0005812=Ldl_recept_b=PD(25.6=18.3)
A:
NO
C2:
PF146701=FXa_inhibition=WD(100=84.1)
Main Inclusion Isoform:
ENSMUST00000080953fB2266
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Chicken
(galGal4)
No conservation detected
Chicken
(galGal3)
No conservation detected
Zebrafish
(danRer10)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
AATGTACAGCGTTCCCCAACC
R:
CAGAAAGGTTCCACCCTGAGG
Band lengths:
167-249
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Pre-implantation embryo development
- Ribosome-engaged transcriptomes of neuronal types
- Neural differentiation time course
- Muscular differentiation time course
- Spermatogenesis cell types
- Reprogramming of fibroblasts to iPSCs
- Hematopoietic precursors and cell types