MmuEX0026876 @ mm10
Exon Skipping
Gene
ENSMUSG00000027070 | Lrp2
Description
low density lipoprotein receptor-related protein 2 [Source:MGI Symbol;Acc:MGI:95794]
Coordinates
chr2:69505081-69506756:-
Coord C1 exon
chr2:69506379-69506756
Coord A exon
chr2:69505919-69505933
Coord C2 exon
chr2:69505081-69505329
Length
15 bp
Sequences
Splice sites
3' ss Seq
TTATTAACGCTCACTCTCAGATG
3' ss Score
6.91
5' ss Seq
AAGGTATGA
5' ss Score
9.11
Exon sequences
Seq C1 exon
CGACCAGGCCTCCTGGTATGTGCCACCCAGATGAGTTTCAGTGCCAGGGAGATGGTACCTGCATCCCTAACACCTGGGAGTGTGATGGGCACCCGGACTGTATCCAGGGCTCGGATGAACACAACGGCTGTGTTCCTAAGACCTGCTCCCCGTCTCATTTCCTCTGTGACAATGGAAACTGCATCTACAACTCGTGGGTCTGTGATGGGGACAATGATTGCAGGGACATGAGTGATGAGAAGGACTGTCCTACCCAGCCTTTTCACTGTCCTAGCTCACAGTGGCAGTGCCCAGGCTACAGCATCTGTGTCAATCTGAGCGCCCTGTGTGACGGCGTCTTTGACTGTCCCAATGGGACCGATGAGTCCCCGCTTTGCA
Seq A exon
ATGAACCACAGCAAG
Seq C2 exon
ATCAAGACAGCTGCTTACATTTTAATGGTGGCTGTACTCACCGGTGCATACAAGGGCCCTTTGGAGCCACCTGCGTGTGTCCAATAGGATACCAACTTGCCAATGATACCAAGACCTGTGAAGATGTAAATGAGTGTGATATTCCAGGCTTTTGCAGCCAGCACTGTGTCAACATGAGAGGGTCCTTCCGGTGCGCTTGTGACCCAGAATATACATTGGAAAGTGATGGGCGGACTTGCAAAGTCACAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSMUSG00000027070-'30-28,'30-27,32-28
Average complexity
S
Mappability confidence:
100%=100=100%
Protein Impact
Alternative protein isoforms (No Ref)
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=0.000 C2=0.000
Domain overlap (PFAM):
C1:
PF0005713=Ldl_recept_a=WD(100=30.7),PF0005713=Ldl_recept_a=WD(100=29.1),PF0005713=Ldl_recept_a=PU(88.4=29.9)
A:
NO
C2:
PF0005713=Ldl_recept_a=PD(9.3=4.8),PF146701=FXa_inhibition=WD(100=42.9),PF146701=FXa_inhibition=WD(100=41.7)
Main Inclusion Isoform:
ENSMUST00000080953fB2268
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
GGCGTCTTTGACTGTCCCAAT
R:
CTCCAAAGGGCCCTTGTATGC
Band lengths:
112-127
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Pre-implantation embryo development
- Ribosome-engaged transcriptomes of neuronal types
- Neural differentiation time course
- Muscular differentiation time course
- Spermatogenesis cell types
- Reprogramming of fibroblasts to iPSCs
- Hematopoietic precursors and cell types