Special

MmuEX0027254 @ mm9

Exon Skipping

Gene
ENSMUSG00000002020 | Ltbp2
Description
latent transforming growth factor beta binding protein 2 [Source:MGI Symbol;Acc:MGI:99502]
Coordinates
chr12:86134894-86140441:-
Coord C1 exon
chr12:86140322-86140441
Coord A exon
chr12:86135991-86136110
Coord C2 exon
chr12:86134894-86135016
Length
120 bp
Sequences
Splice sites
3' ss Seq
GAGGGGTTGTTGTTTTATAGATA
3' ss Score
5.74
5' ss Seq
TAGGTAAGG
5' ss Score
9.31
Exon sequences
Seq C1 exon
ATATCGATGAGTGTGAGCAGCCCGGGGTGTGCAGTGGTGGGCGATGCAGCAACACGGAGGGCTCGTACCACTGCGAGTGTGATCGGGGCTACATCATGGTCAGGAAAGGACACTGTCAAG
Seq A exon
ATATCAACGAATGCCGTCACCCTGGTACCTGCCCTGATGGGAGATGCGTCAACTCCCCTGGCTCCTACACTTGTCTGGCCTGTGAGGAGGGCTATGTAGGCCAGAGTGGGAGCTGTGTAG
Seq C2 exon
ATGTCAATGAGTGTCTGACCCCTGGGATATGTACCCATGGAAGGTGCATCAACATGGAAGGCTCCTTTAGATGCTCCTGTGAGCCGGGCTATGAGGTCACCCCAGACAAGAAGGGCTGCCGAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSMUSG00000002020-'21-21,'21-20,23-21=AN
Average complexity
A_S
Mappability confidence:
100%=100=100%
Protein Impact





	

	
Alternative protein isoforms (Ref)





No structure available

		

			
Features


			

				
Disorder rate (Iupred):
  C1=0.000 A=0.000 C2=0.000
 
                        

				
Domain overlap (PFAM):

					





						

							
C1:
PF062476=Plasmod_Pvs28=FE(32.0=100),PF0764510=EGF_CA=WD(100=95.1),PF0764510=EGF_CA=PU(0.1=0.0)

							
A:
PF062476=Plasmod_Pvs28=FE(32.0=100),PF0764510=EGF_CA=WD(100=95.1),PF0764510=EGF_CA=PU(0.1=0.0)

							
C2:
PF062476=Plasmod_Pvs28=PD(6.4=19.0),PF0764510=EGF_CA=WD(100=95.2),PF0764510=EGF_CA=PU(0.1=0.0)

						

					

				








    
Main Inclusion Isoform:
ENSMUSP00000128882





     
                   









    
Main Skipping Isoform:
ENSMUSP00000128882f99A





     
      









    
Other Inclusion Isoforms:
ENSMUSP00000002073, ENSMUSP00000105883, ENSMUSP00000127693, ENSMUSP00000132690
          









    
Other Skipping Isoforms:
NA
  



Associated events






Other assemblies


mm10




Conservation


Human
(hg38)
chr14:74511245-74511364 
HIGH PSI
HsaEX0036905
(LTBP2)
Human
(hg19)
chr14:74977948-74978067 
HIGH PSI
HsaEX0036905
(LTBP2)
Rat
(rn6)
chr6:108515925-108516044 
HIGH PSI
RnoEX6029361
(Ltbp2)
Cow
(bosTau6)
chr10:86199498-86199617 
HIGH PSI
BtaEX6055044
(LTBP2)
Chicken
(galGal4)
chr5:37221225-37221344 
HIGH PSI
GgaEX1034372
(LTBP2)
Chicken
(galGal3)
chr5:40350021-40350140 
HIGH PSI
GgaEX1034372
(LTBP2)
Zebrafish
(danRer10)
No conservation detected
Fruitfly
(dm6)
No conservation detected




Primers PCR

	

		

			
Suggestions for RT-PCR validation

			

				
F: 
TATCGATGAGTGTGAGCAGCC

				
R: 
CTCGGCAGCCCTTCTTGTCT

				
Band lengths: 
242-362

			

		

	





	
Functional annotations
(Submit an annotation)

	


There are 0 annotated functions for this event 


		










GENOMIC CONTEXT[edit]












INCLUSION PATTERN[edit]






SPECIAL DATASETS
  • Pre-implantation embryo development
  • Neural differentiation time course
  • Muscular differentiation time course
  • Spermatogenesis cell types
  • Reprogramming of fibroblasts to iPSCs
  • Hematopoietic precursors and cell types






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