Special

MmuEX0027263 @ mm9

Exon Skipping

Gene
ENSMUSG00000002020 | Ltbp2
Description
latent transforming growth factor beta binding protein 2 [Source:MGI Symbol;Acc:MGI:99502]
Coordinates
chr12:86128316-86130177:-
Coord C1 exon
chr12:86130034-86130177
Coord A exon
chr12:86128854-86129045
Coord C2 exon
chr12:86128316-86128399
Length
192 bp
Sequences
Splice sites
3' ss Seq
GGGGCTTCTGTCACACACAGCTC
3' ss Score
5.23
5' ss Seq
CAGGTAAGG
5' ss Score
11.08
Exon sequences
Seq C1 exon
ATGTGAACGAGTGTGAGCTCATGATGGCAGTGTGTGGGGATGCGCTCTGTGAGAACGTGGAAGGCTCCTTCCTGTGCCTTTGCGCCAGTGACCTTGAGGAGTACGACGCAGAAGAAGGACACTGCCGTCCTCGGGTGGCTGGAG
Seq A exon
CTCAGAGAATCCCAGAGGTCCGGACAGAGGACCAGGCTCCAAGCCTTATCCGCATGGAATGCTACTCTGAACACAATGGTGGTCCTCCCTGCTCTCAAATCCTGGGCCAGAACTCCACACAGGCCGAGTGCTGCTGCACTCAGGGTGCCAGATGGGGAAAGGCCTGTGCGCCCTGCCCATCTGAGGACTCAG
Seq C2 exon
TTGAATTCAGTCAGCTCTGCCCCAGTGGTCAAGGTTACATCCCAGTGGAAGGAGCCTGGACATTTGGACAAACCATGTATACAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSMUSG00000002020-'34-33,'34-32,35-33=AN
Average complexity
A_S
Mappability confidence:
100%=100=100%
Protein Impact





	

	
Alternative protein isoforms (Ref)





No structure available

		

			
Features


			

				
Disorder rate (Iupred):
  C1=0.000 A=0.046 C2=0.000
 
                        

				
Domain overlap (PFAM):

					





						

							
C1:
PF0764510=EGF_CA=WD(100=85.7)

							
A:
PF0068312=TB=PU(85.4=53.8)

							
C2:
PF0068312=TB=PD(12.2=17.2),PF0764510=EGF_CA=PU(0.1=0.0)

						

					

				








    
Main Inclusion Isoform:
ENSMUSP00000128882





     
                   









    
Main Skipping Isoform:
NA





     
      









    
Other Inclusion Isoforms:
ENSMUSP00000002073, ENSMUSP00000105883, ENSMUSP00000127693, ENSMUSP00000132067
          









    
Other Skipping Isoforms:
NA
  



Associated events






Other assemblies


mm10




Conservation


Human
(hg38)
chr14:74504983-74505169 
HsaEX0036916
(LTBP2)
Human
(hg19)
chr14:74971686-74971877 
HIGH PSI
HsaEX0036916
(LTBP2)
Rat
(rn6)
No conservation detected
Cow
(bosTau6)
chr10:86192129-86192320 
HIGH PSI
BtaEX6055053
(LTBP2)
Chicken
(galGal4)
chr5:37216046-37216237 
HIGH PSI
GgaEX0015302
(LTBP2)
Chicken
(galGal3)
chr5:40344123-40344314 
HIGH PSI
GgaEX0015302
(LTBP2)
Zebrafish
(danRer10)
No conservation detected
Fruitfly
(dm6)
No conservation detected




Primers PCR

	

		

			
Suggestions for RT-PCR validation

			

				
F: 
ATGTGAACGAGTGTGAGCTCA

				
R: 
GGTTTGTCCAAATGTCCAGGC

				
Band lengths: 
218-410

			

		

	





	
Functional annotations
(Submit an annotation)

	


There are 0 annotated functions for this event 


		










GENOMIC CONTEXT[edit]












INCLUSION PATTERN[edit]






SPECIAL DATASETS
  • Pre-implantation embryo development
  • Neural differentiation time course
  • Muscular differentiation time course
  • Spermatogenesis cell types
  • Reprogramming of fibroblasts to iPSCs
  • Hematopoietic precursors and cell types






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