Special

MmuEX0027278 @ mm10

Exon Skipping

Gene
ENSMUSG00000040488 | Ltbp4
Description
latent transforming growth factor beta binding protein 4 [Source:MGI Symbol;Acc:MGI:1321395]
Coordinates
chr7:27314237-27319756:-
Coord C1 exon
chr7:27319625-27319756
Coord A exon
chr7:27319411-27319536
Coord C2 exon
chr7:27314237-27314383
Length
126 bp
Sequences
Splice sites
3' ss Seq
CGGCCTGCTGGTGTTTGCAGATG
3' ss Score
8.57
5' ss Seq
TGGGTAAGG
5' ss Score
9.08
Exon sequences
Seq C1 exon
ACATTGATGAGTGCCGAGAATACGGCTCTGCGATTTGTGGTGCCCAGCGCTGTGAGAACACCCCGGGCTCCTACCGCTGCACACCAGCCTGCGACCCTGGCTATCAGCCTACACCAGGGGGCGGGTGCCAAG
Seq A exon
ATGTGGATGAATGCCGGAACCGGTCTTTCTGCGGCGCCCATGCTATGTGCCAGAATCTGCCTGGGTCCTTTCAGTGCGTCTGTGACCAAGGCTACGAAGGGGCACGGGACGGACGTCACTGCGTGG
Seq C2 exon
ATGTGAATGAGTGTGAGACACTACAGGGCGTGTGTGGCTCCGCGCTGTGTGAAAATGTTGAAGGCTCCTTCCTGTGTGTCTGCCCCAATAGCCCTGAGGAATTTGATCCCATGACTGGACGCTGTGTTCCCCCACGGGCTCCTGCAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSMUSG00000040488-'41-49,'41-45,42-49
Average complexity
S
Mappability confidence:
100%=100=100%
Protein Impact





	

	
Alternative protein isoforms (Ref)





No structure available

		

			
Features


			

				
Disorder rate (Iupred):
  C1=0.000 A=0.000 C2=0.176
 
                        

				
Domain overlap (PFAM):

					





						

							
C1:
PF0764510=EGF_CA=WD(100=95.6),PF0764510=EGF_CA=PU(0.1=0.0)

							
A:
PF0764510=EGF_CA=WD(100=95.3),PF0764510=EGF_CA=PU(0.1=0.0)

							
C2:
PF0764510=EGF_CA=WD(100=84.0)

						

					

				








    
Main Inclusion Isoform:
ENSMUSP00000037536





     
                   









    
Main Skipping Isoform:
NA





     
      









    
Other Inclusion Isoforms:
ENSMUSP00000104006, ENSMUSP00000113523, ENSMUSP00000113674, ENSMUSP00000113746
          









    
Other Skipping Isoforms:
NA
  



Associated events






Other assemblies


mm9




Conservation


Human
(hg38)
chr19:40617100-40617225 
ALTERNATIVE
HsaEX0036952
(LTBP4)
Human
(hg19)
chr19:41123006-41123130 
ALTERNATIVE
HsaEX0036952
(LTBP4)
Rat
(rn6)
chr1:84131996-84132121 
HIGH PSI
RnoEX0051405
(Ltbp4)
Cow
(bosTau6)
chr18:50191935-50192056 
HIGH PSI
BtaEX0020887
(LTBP4)
Chicken
(galGal4)
chr5:37217211-37217336 
HIGH PSI
GgaEX1034367
(LTBP2)
Chicken
(galGal3)
chr5:40345288-40345413 
HIGH PSI
GgaEX1034367
(LTBP2)
Zebrafish
(danRer10)
chr18:49023318-49023443 
HIGH PSI
DreEX6066936
(LTBP4)
Fruitfly
(dm6)
No conservation detected




Primers PCR

	

		

			
Suggestions for RT-PCR validation

			

				
F: 
ATACGGCTCTGCGATTTGTGG

				
R: 
GGAACACAGCGTCCAGTCATG

				
Band lengths: 
243-369

			

		

	





	
Functional annotations
(Submit an annotation)

	


There are 0 annotated functions for this event 


		










GENOMIC CONTEXT[edit]












INCLUSION PATTERN[edit]






SPECIAL DATASETS
  • Pre-implantation embryo development
  • Ribosome-engaged transcriptomes of neuronal types
  • Neural differentiation time course
  • Muscular differentiation time course
  • Spermatogenesis cell types
  • Reprogramming of fibroblasts to iPSCs
  • Hematopoietic precursors and cell types





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