Special

MmuEX0028740 @ mm9

Exon Skipping

Gene
ENSMUSG00000020691 | Mettl2
Description
methyltransferase like 2 [Source:MGI Symbol;Acc:MGI:1289171]
Coordinates
chr11:104988090-104990389:+
Coord C1 exon
chr11:104988090-104988181
Coord A exon
chr11:104989109-104989277
Coord C2 exon
chr11:104990055-104990389
Length
169 bp
Sequences
Splice sites
3' ss Seq
CCAGTATCCTCTTTTCGCAGTTA
3' ss Score
6.24
5' ss Seq
GAGGTAAGC
5' ss Score
9.85
Exon sequences
Seq C1 exon
GGACAACGTGAAGTGGTCCGAGGAGCAGGCCGCGGCGGCGGAGAGGAAAGTGCAGGAGAACAGCTCCCCGCTGGTGTGCCCGGAGAAGCAAG
Seq A exon
TTAAAGGACCAGTTAGCCAAGTGCAGTGGTGTATTCCTGTAGACTCAGCTCCGTGGGAGGCTGAGGCAGAAGGATCACTGAATTGGAGGCCATCCTGGGCAGCATAGGGTGATCTAGTCTCCAAAACGATTAAACTTGGACCACGGGGCCTTAAGTGCTTTGCCTAGAG
Seq C2 exon
TTGATTATGAAGTCAATGCCCATAAATACTGGGATGACTTCTACAGAATCCATGAAAATGGGTTTTTCAAGGATAGACACTGGCTTTTTACTGAGTTCCCTGAATTGGCACCTAGCCACAGTCACCTGACGGGTGTACCCTTGGAGAAGCAGAGGAGTGACGTCTGTGAGGACGGACCTGGCTTGACAGCAGAACAGCACAAGTGTTCTTGTGCCAGCCCTGGATGTGAGACTCAGGTGCCTCCCTTGGAAGAGCCAGTGACTCAGAAGCTCGGTCACCTAGAAATTAGTGGTGAGGAATTTCCTGGCTCCTCTGCCACCTACCGAATACTTGAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSMUSG00000020691-'2-2,'2-1,4-2
Average complexity
C1
Mappability confidence:
100%=100=100%
Protein Impact





	

	
ORF disruption upon sequence inclusion





No structure available

		

			
Features


			

				
Disorder rate (Iupred):
  C1=0.604 A=0.257 C2=0.161
 
                        

				
Domain overlap (PFAM):

					





						

							
C1:
NO

							
A:
NO

							
C2:
PF134891=Methyltransf_23=PU(15.0=25.0)

						

					

				








    
Main Inclusion Isoform:
ENSMUSP00000021030f816A





     
                   









    
Main Skipping Isoform:
ENSMUSP00000021030





     
      









    
Other Inclusion Isoforms:
NA
          









    
Other Skipping Isoforms:
ENSMUSP00000021030f817A
  



Associated events






Other assemblies


mm10




Conservation


Human
(hg38)
No conservation detected
Human
(hg19)
No conservation detected
Rat
(rn6)
No conservation detected
Cow
(bosTau6)
chr19:47513590-47513633 
ALTERNATIVE
BtaEX0022000
(METTL2)
Chicken
(galGal4)
No conservation detected
Chicken
(galGal3)
No conservation detected
Zebrafish
(danRer10)
No conservation detected
Fruitfly
(dm6)
No conservation detected




Primers PCR

	

		

			
Suggestions for RT-PCR validation

			

				
F: 
GACAACGTGAAGTGGTCCGAG

				
R: 
ACAGACGTCACTCCTCTGCTT

				
Band lengths: 
258-427

			

		

	





	
Functional annotations
(Submit an annotation)

	


There are 0 annotated functions for this event 


		










GENOMIC CONTEXT[edit]












INCLUSION PATTERN[edit]






SPECIAL DATASETS
  • Pre-implantation embryo development
  • Neural differentiation time course
  • Muscular differentiation time course
  • Spermatogenesis cell types
  • Reprogramming of fibroblasts to iPSCs
  • Hematopoietic precursors and cell types






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