Special

MmuEX0030360 @ mm10

Exon Skipping

Gene
Description
myosin, heavy polypeptide 4, skeletal muscle [Source:MGI Symbol;Acc:MGI:1339713]
Coordinates
chr11:67255832-67257018:+
Coord C1 exon
chr11:67255832-67255956
Coord A exon
chr11:67256400-67256495
Coord C2 exon
chr11:67256945-67257018
Length
96 bp
Sequences
Splice sites
3' ss Seq
GGATTAAGAAGAAGATGGAGGGA
3' ss Score
-36.13
5' ss Seq
AAGGTACCT
5' ss Score
8.49
Exon sequences
Seq C1 exon
AGGAGATCTCTGACCTGACCGAGCAGATTGCTGAGGGAGGGAAGCACATCCATGAGCTGGAGAAAATCAAGAAGCAAATTGATCAGGAAAAGAGTGAATTACAGGCTTCTCTGGAGGAAGCGGAG
Seq A exon
GGAGACCTCAATGAGATGGAGATCCAGCTGAACCATGCCAACCGCCAGGCTGCGGAGGCAATCAGGAACCTTCGGAACACCCAGGGAATGCTGAAG
Seq C2 exon
GCATCCAAGAACAAGTCATTAAGGGTACTTGTAGATACTCCTATTTAATCAGACTCTGAGCTAATAAGATCCAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSMUSG00000057003-'53-51,'53-50,54-51
Average complexity
C3*
Mappability confidence:
100%=100=100%
Protein Impact

Alternative protein isoforms (Ref)

No structure available
Features
Disorder rate (Iupred):
  C1=0.571 A=0.466 C2=NA
Domain overlap (PFAM):

C1:
PF0157614=Myosin_tail_1=FE(4.8=100),PF0003816=Filament=FE(13.3=100)
A:
PF0157614=Myosin_tail_1=FE(11.9=100),PF0003816=Filament=PD(10.0=30.1)
C2:
NA


Main Inclusion Isoform:


Main Skipping Isoform:
NA


Other Inclusion Isoforms:


Other Skipping Isoforms:
NA
Associated events
Conservation
Rat
(rn6)
No conservation detected
Chicken
(galGal4)
Chicken
(galGal3)
No conservation detected
Zebrafish
(danRer10)
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
TCTGACCTGACCGAGCAGATT
R:
AGCTCAGAGTCTGATTAAATAGGAGT
Band lengths:
179-275
Functional annotations
There are 0 annotated functions for this event


GENOMIC CONTEXT[edit]

INCLUSION PATTERN[edit]


SPECIAL DATASETS

  • Pre-implantation embryo development
  • Ribosome-engaged transcriptomes of neuronal types
  • Neural differentiation time course
  • Muscular differentiation time course
  • Spermatogenesis cell types
  • Reprogramming of fibroblasts to iPSCs
  • Hematopoietic precursors and cell types