Special

MmuEX0035470 @ mm9

Exon Skipping

Gene
ENSMUSG00000026991 | Pkp4
Description
plakophilin 4 [Source:MGI Symbol;Acc:MGI:109281]
Coordinates
chr2:59149751-59156701:+
Coord C1 exon
chr2:59149751-59149970
Coord A exon
chr2:59152413-59152460
Coord C2 exon
chr2:59156569-59156701
Length
48 bp
Sequences
Splice sites
3' ss Seq
GAATTTTTTTTTTCTTTCAGTAC
3' ss Score
8.75
5' ss Seq
TTGGTGAGA
5' ss Score
6.29
Exon sequences
Seq C1 exon
TAGGTATTGGAAATCTACAAAGGACATCCAGCCAGCGAAGCACCCTTACATACCAAAGAAATAACTATGCCCTGAACACAGCAGCTACCTATGCGGAGCCCTACAGGCCAGTTCAGTACCGAGTCCAAGAGTGCAGCTATAACAGGCTGCAGCACACAGGGCCAGCTGATGACGGTGCCACAAGATCCCCATCAATAGACAGCATTCAGAAGGACCCCAG
Seq A exon
TACTTTAAAAGGTGTTATTCATTGTCTTCAGACATCTGTTGTTTTTTG
Seq C2 exon
GGAGTTTGCCTGGCGTGACCCTGAGCTGCCAGAAGTCATTCACATGCTGCAGCACCAGTTCCCATCGGTCCAGGCAAATGCCGCAGCCTACCTGCAGCATCTGTGCTTTGGTGACAACAAAGTGAAGATGGAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSMUSG00000026991_MULTIEX3-5/5=4-C2
Average complexity
S
Mappability confidence:
100%=100=100%
Protein Impact





	

	
Alternative protein isoforms (No Ref)





No structure available

		

			
Features


			

				
Disorder rate (Iupred):
  C1=0.496 A=0.000 C2=0.013
 
                        

				
Domain overlap (PFAM):

					





						

							
C1:
PF0051418=Arm=PU(9.8=5.4)

							
A:
NO

							
C2:
PF0051418=Arm=PD(87.8=80.0),PF0051418=Arm=PU(14.6=13.3)

						

					

				








    
Main Inclusion Isoform:
ENSMUSP00000042249





     
                   









    
Main Skipping Isoform:
ENSMUSP00000099815





     
      









    
Other Inclusion Isoforms:
ENSMUSP00000122152, ENSMUSP00000131442
          









    
Other Skipping Isoforms:
ENSMUSP00000099815f2036A, ENSMUSP00000108196, ENSMUSP00000129836
  



Associated events







Other assemblies


mm10




Conservation


Human
(hg38)
No conservation detected
Human
(hg19)
chr2:159492845-159492891 
Rat
(rn6)
No conservation detected
Cow
(bosTau6)
chr2:37863950-37863998 
Chicken
(galGal4)
No conservation detected
Chicken
(galGal3)
No conservation detected
Zebrafish
(danRer10)
No conservation detected
Fruitfly
(dm6)
No conservation detected




Primers PCR

	

		

			
Suggestions for RT-PCR validation

			

				
F: 
AGTACCGAGTCCAAGAGTGCA

				
R: 
AATGACTTCTGGCAGCTCAGG

				
Band lengths: 
146-194

			

		

	





	
Functional annotations
(Submit an annotation)

	


There are 0 annotated functions for this event 


		










GENOMIC CONTEXT[edit]












INCLUSION PATTERN[edit]






SPECIAL DATASETS
  • Pre-implantation embryo development
  • Neural differentiation time course
  • Muscular differentiation time course
  • Spermatogenesis cell types
  • Reprogramming of fibroblasts to iPSCs
  • Hematopoietic precursors and cell types






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