Special

MmuEX0043437 @ mm10

Exon Skipping

Gene
ENSMUSG00000023032 | Slc4a8
Description
solute carrier family 4 (anion exchanger), member 8 [Source:MGI Symbol;Acc:MGI:1928745]
Coordinates
chr15:100806250-100809363:+
Coord C1 exon
chr15:100806250-100806411
Coord A exon
chr15:100807201-100807452
Coord C2 exon
chr15:100809295-100809363
Length
252 bp
Sequences
Splice sites
3' ss Seq
GGGTGACTCTCTCCCCACAGAAA
3' ss Score
9.87
5' ss Seq
AAGGTATTC
5' ss Score
6.8
Exon sequences
Seq C1 exon
CCAACAAGGGACGATCGAGGATGGTTTATTAATCCCATTGGCCCCAATCCCTGGTGGACTGTGATAGCCGCAATTATCCCAGCTCTCCTGTGCACTATCCTGATATTCATGGACCAGCAGATCACCGCTGTCATCATTAACAGGAAGGAACACAAGCTCAAG
Seq A exon
AAAGGCTGTGGCTACCACCTGGACCTGCTCATGGTGGCCGTCATGCTGGGAGTTTGCTCCATCATGGGCCTGCCTTGGTTTGTGGCCGCGACCGTCCTGTCCATTACCCATGTGAACAGCCTCAAGCTGGAATCCGAATGCTCTGCCCCCGGGGAGCAGCCCAAGTTCTTGGGCATCCGGGAACAGAGAGTCACAGGGCTTATGATCTTCGTGCTGATGGGCTGCTCAGTCTTCATGACAGCTGTCTTAAAG
Seq C2 exon
TTTATCCCGATGCCAGTGCTCTACGGAGTTTTCCTCTACATGGGAGTCTCTTCGCTACAAGGAATCCAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSMUSG00000023032_CASSETTE4
Average complexity
S*
Mappability confidence:
100%=100=100%
Protein Impact





	

	
Alternative protein isoforms (Ref)





No structure available

		

			
Features


			

				
Disorder rate (Iupred):
  C1=0.000 A=0.000 C2=0.000
 
                        

				
Domain overlap (PFAM):

					





						

							
C1:
PF0095516=HCO3_cotransp=FE(10.3=100)

							
A:
PF0095516=HCO3_cotransp=FE(16.1=100)

							
C2:
PF0095516=HCO3_cotransp=FE(4.3=100)

						

					

				








    
Main Inclusion Isoform:
ENSMUSP00000023776





     
                   









    
Main Skipping Isoform:
ENSMUST00000023776fB16981





     
      









    
Other Inclusion Isoforms:
ENSMUSP00000125090
          









    
Other Skipping Isoforms:
NA
  



Associated events






Other assemblies


mm9




Conservation


Human
(hg38)
chr12:51489700-51489951 
ALTERNATIVE
HsaEX0059854
(SLC4A8)
Human
(hg19)
chr12:51883484-51883735 
ALTERNATIVE
HsaEX0059854
(SLC4A8)
Rat
(rn6)
chr7:142454723-142454974 
HIGH PSI
RnoEX6034118
(Slc4a8)
Cow
(bosTau6)
chr5:28480302-28480553 
ALTERNATIVE
BtaEX0033360
(SLC4A8)
Chicken
(galGal4)
chrLGE22C19W28_E50C23:857518-857769 
HIGH PSI
GgaEX7011996
(SLC4A8)
Chicken
(galGal3)
chr2:38446278-38446529 
HIGH PSI
GgaEX6019427
(SLC4A7)
Zebrafish
(danRer10)
chr6:40399214-40399465 
HIGH PSI
DreEX6023326
(slc4a8)
Fruitfly
(dm6)
No conservation detected




Primers PCR

	

		

			
Suggestions for RT-PCR validation

			

				
F: 
ACAAGGGACGATCGAGGATGG

				
R: 
CTGGATTCCTTGTAGCGAAGAGAC

				
Band lengths: 
228-480

			

		

	





	
Functional annotations
(Submit an annotation)

	


There are 0 annotated functions for this event 


		










GENOMIC CONTEXT[edit]












INCLUSION PATTERN[edit]






SPECIAL DATASETS
  • Pre-implantation embryo development
  • Ribosome-engaged transcriptomes of neuronal types
  • Neural differentiation time course
  • Muscular differentiation time course
  • Spermatogenesis cell types
  • Reprogramming of fibroblasts to iPSCs
  • Hematopoietic precursors and cell types





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