MmuEX0049253 @ mm10
Exon Skipping
Gene
ENSMUSG00000026812 | Tsc1
Description
tuberous sclerosis 1 [Source:MGI Symbol;Acc:MGI:1929183]
Coordinates
chr2:28671766-28672903:+
Coord C1 exon
chr2:28671766-28671881
Coord A exon
chr2:28672393-28672504
Coord C2 exon
chr2:28672785-28672903
Length
112 bp
Sequences
Splice sites
3' ss Seq
ACATTCTGATTTGATTGTAGGCT
3' ss Score
6.9
5' ss Seq
CTGGTATGT
5' ss Score
8.14
Exon sequences
Seq C1 exon
GGGGTTCTACTTCCACCCCTTCCTCCAGCTCTCGGCTGATGTTGTTCAGTCCACCTGGGCAGCTACCTCAGAGTTTGAGTTCCCCATCAACACGGCTGTTACCTGAGCCGCTGCAA
Seq A exon
GCTAGTCTCTGGAGCCCATCTGCGGTCTGTGGTATGACCACTCCTCCTACGTCTCCTGGAAATGTCCCAGCTGATTTGTCACATCCGTATAGTAAAGCCTTTGGTACCACTG
Seq C2 exon
GTGGAAAAGGAACTCCTTCAGGAACCCCAGCGACCTCTCCTCCTCCAGCCCCACCTTGTCCCCAAGATGACTGTGTGCATGGTTCAGCAGCCCAGGCCTCAGCCACAGCCCCCAGGAAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSMUSG00000026812_CASSETTE3
Average complexity
S*
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence exclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.933 A=0.892 C2=1.000
Domain overlap (PFAM):
C1:
PF043887=Hamartin=PD(12.4=66.2)
A:
PF043887=Hamartin=FE(5.2=100)
C2:
PF043887=Hamartin=FE(5.5=100)
Main Skipping Isoform:
NA
Other Inclusion Isoforms:
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
GGGTTCTACTTCCACCCCTTC
R:
CTTCCTGGGGGCTGTGGC
Band lengths:
234-346
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Pre-implantation embryo development
- Ribosome-engaged transcriptomes of neuronal types
- Neural differentiation time course
- Muscular differentiation time course
- Spermatogenesis cell types
- Reprogramming of fibroblasts to iPSCs
- Hematopoietic precursors and cell types