Special

MmuEX6049640 @ mm9

Exon Skipping

Gene
ENSMUSG00000020125 | Elane
Description
elastase, neutrophil expressed [Source:MGI Symbol;Acc:MGI:2679229]
Coordinates
chr10:79349728-79350961:+
Coord C1 exon
chr10:79349728-79349869
Coord A exon
chr10:79350311-79350544
Coord C2 exon
chr10:79350662-79350961
Length
234 bp
Sequences
Splice sites
3' ss Seq
CCCCGTGTCTTCCACTGTAGCTC
3' ss Score
9.29
5' ss Seq
TTCGTAAGT
5' ss Score
9.77
Exon sequences
Seq C1 exon
AAATTTCCGGTCAGTGCAGGTAGTGCTGGGAGCCCATGACCTGCGGCGACAGGAGCGCACTCGACAGACCTTCTCTGTGCAGCGGATCTTCGAGAATGGCTTTGACCCATCACAACTGCTGAACGACATTGTGATTATCCAG
Seq A exon
CTCAATGGCTCCGCTACCATTAACGCCAACGTGCAGGTGGCCCAGCTGCCTGCCCAGGGCCAGGGCGTGGGTGACAGAACTCCATGTCTGGCCATGGGCTGGGGCAGGTTGGGCACAAACAGACCATCACCCAGTGTGCTACAAGAGCTCAATGTGACAGTGGTGACTAACATGTGCCGCCGTCGTGTGAACGTATGCACTCTGGTGCCACGTCGGCAGGCAGGCATCTGCTTC
Seq C2 exon
GGGGACTCTGGCGGACCCTTGGTCTGTAACAACCTTGTCCAAGGCATTGACTCCTTCATCCGAGGAGGCTGTGGATCTGGATTGTACCCAGATGCCTTCGCCCCTGTGGCTGAGTTTGCAGATTGGATCAATTCCATTATCCGAAGCCATAATGACCACCTTCTTACCCATCCCAAAGACCGAGAGGGCAGGACCAACTAGGACCTGTCTGCACTCCCACCCCGCTCCCCTTGCTCCCTTGCTCCCCCCTCTACCAGAGACCTCTCCATTTTACTACAATAAAAGCAGCCTTTGTTTTGT
VastDB Features
Vast-tools module Information
Secondary ID
ENSMUSG00000020125-'2-3,'2-2,3-3=AN
Average complexity
A_S
Mappability confidence:
100%=100=100%
Protein Impact





	

	
Alternative protein isoforms (Ref)





No structure available

		

			
Features


			

				
Disorder rate (Iupred):
  C1=0.000 A=0.000 C2=0.197
 
                        

				
Domain overlap (PFAM):

					





						

							
C1:
PF0008921=Trypsin=FE(22.0=100)

							
A:
PF0008921=Trypsin=FE(36.0=100)

							
C2:
PF0008921=Trypsin=PD(19.6=62.7)

						

					

				








    
Main Inclusion Isoform:
ENSMUSP00000038925





     
                   









    
Main Skipping Isoform:
NA





     
      









    
Other Inclusion Isoforms:
NA
          









    
Other Skipping Isoforms:
NA
  



Associated events






Other assemblies


mm10




Conservation


Human
(hg38)
chr19:855564-855794 
HIGH PSI
HsaEX6091394
(ELANE)
Human
(hg19)
chr19:855564-855794 
HIGH PSI
HsaEX6091394
(ELANE)
Rat
(rn6)
chr7:12638723-12638956 
ALTERNATIVE
RnoEX0031625
(Elane)
Cow
(bosTau6)
chr7:44989880-44990110 
HIGH PSI
BtaEX6040152
(ELA2)
Chicken
(galGal4)
No conservation detected
Chicken
(galGal3)
chr28:2321142-2321268 
Zebrafish
(danRer10)
No conservation detected
Fruitfly
(dm6)
No conservation detected




Primers PCR

	

		

			
Suggestions for RT-PCR validation

			

				
F: 
CCCATCACAACTGCTGAACGA

				
R: 
AGAGGTCTCTGGTAGAGGGGG

				
Band lengths: 
302-536

			

		

	





	
Functional annotations
(Submit an annotation)

	


There are 0 annotated functions for this event 


		










GENOMIC CONTEXT[edit]












INCLUSION PATTERN[edit]










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