Special

MmuEX6069879 @ mm9

Exon Skipping

Gene
ENSMUSG00000079243 | Xirp1
Description
xin actin-binding repeat containing 1 [Source:MGI Symbol;Acc:MGI:1333878]
Coordinates
chr9:119922873-119932716:-
Coord C1 exon
chr9:119932552-119932716
Coord A exon
chr9:119925544-119928937
Coord C2 exon
chr9:119922873-119925152
Length
3394 bp
Sequences
Splice sites
3' ss Seq
GGTTCTCCCCTTCTTCCCAGAAG
3' ss Score
7.07
5' ss Seq
AAGGTCAGT
5' ss Score
8.68
Exon sequences
Seq C1 exon
AGATAAAGGCAGCTGCCTGGTTGGCAGAGAACGGAGACCTAGAGCCAAGGTAGAGAGAGGCAGGGGACCCAGGAACAGAACAGAACTGACAACAAAGAATCCCGGCAGAGCGACAGACCCCAAGGCTAGACACCCAAAAGCACCCAGACACCAGCCAGACCCTTG
Seq A exon
AAGGATGGCTGATGCCCAGATGCAGGTAGCTCCTACACCAACCATCCAAATGAGGACAGAAGAGGACCTGTCCCTCCCTCATCCCTCAGCCCCAGAGGGTCTGCCGCCACCACCCCCCAAAGAAACCTTCTCCAAGTTCCAGCAGCAGCGGCAAGCCAGTGAGCTCCGGCGTCTCTACAAACACATCCACCCTGAGCTTCGGAAGAACCTCGAGGAGGCTGTGGCTGAGGACCTGGCGGAGGTCCTCGGTTCGGAGGAGCCCACTGAGGGCGATGTTCAGTGTATGCGCTGGATCTTTGAGAACTGGCGGCTAGATGCCATTGGCGATCACGAGAGGCCGGCTGCCAGGGAACCTGTGTCAGGTGGCAACGTCCAGGCCACCTCTCGAAAGTTTGAGGAAGGCTCCTTTACCAACAGCTCAGATCAGGAGCCGGAGGGACTCCGGCCATCAGGGGGTGATGTCCAAGCTGCCAGACAGATGTTTGAGACCAAGCCACTGGATGCGCTGAGAGGCCAGGAGGAGGCAACACAGACAACCATGAGGGAACCTGCAGCCACTGGAGATGTACAGGGAACCAGAAAGCTCTTTGAGACTAGGCCCCTGGACCGACTGGGCTCCCGCCCCTCTATCCAGGAGCAGAGTCCTTTAGAGCTGCGCTCAGAGATTCAGGAGCTGAAGGGCGATGTGAAGAAGACGGTGAAGCTGTTTCAGACGGAACCTCTATGCGCCATCCAGGATGCCGAGGGCACCATCCACGAAGTCAAGGCTGCCTGTCGGGAGGAGATTCAAAGCAATGCAGTGAGGTCTGCTCGCTGGCTCTTTGAGACCCGACCTCTGGATGCCTTCAACCAGGACCCCAGCCAGGTGCGGGTGATTCGGGGGATCTCCCTTGAGGAGGGAGCCCTGCCGGATGTCAGTGCAACTCGTTGGATCTTTGAGACGCAGCCTTTGGATGCCATTCGTGAGATCGAGGTGGACGAGAAGGACTTCCAGCCATCTCCGGATCTCATCCCTCCTGGCCCAGATGTTCAGCATCAGCGACATCTGTTTGAAACCTGTTCCCTGGACACTCTGAAGGGTGAAAGAGAAACAGAGGCAGAGGTGCCACCCAAGGAGGAGGTGATTCCTGGCGATGTCCGCTCTACACTCTGGCTATTTGAAACAAAACCCCTGGATGCTTTCAGAGACCAGGTCCAAGTGGGTCACCTGCAACGGGTGGGTCACCAGGAGGGTGAGGGGCTTGTGACAGAGTGTCTACCCAGTAATGGTACTTCGGTGTTGCCTCTGTCTCAGGGTGTCCCCCAGAATGATGGGTTGAAAGGGGATGTGAAAACCTTCAAGAATCTTTTTGAGACCCTTCCCTTAGACAGCATTGGGCAGGGTGAGCCTTCAGCCTATGGGAACATAAACAGAGGACAAAACACTGATTCTGCCGAGCAGTCCCAGGGTTCTGACGCCCCGGTATATGCTATGCAGGACAGCAGGGGACAGCTTCATGCCCTGACTTCTGTCAGCAGAGAGCAGGTAGTTGGAGGTGATGTTCAGGGCTACAAGTGGATGTTTGAGACACAGCCCCTGGACACGCTGGGTAGAAGCCCCAGTACCATCGATGTGGTACGAGGTATCACTCGGCAGGAAGTGGTGGCTGGGGATGTCGGCACCACTCGGTGGCTCTTTGAGACGCAGCCATTGGAGATGATCCACCAACAAGAGCAACAGAAACCAGAGGAGGAAGAGGGGAAGGGTCCAGGAGGCCCCCCCCCTGAGCTCCCCAAAAAGGGTGATGTACAGACTATCCGTTGGCTGTTTGAGACCTACCCTATGAGCGAGTTGGCAGAGAAGCGAGAATCTGAGGTCACAGACCCCGTGAGCAAGGCTGAGACACAGTCCTGCACCTGGATGTTTGGGCCCCAATCTCTGAACCCAGCAGAAGGCTCTGGGGAGCAGCACCTGCAAACCAGCCAGGTTCCGGCTGGAGACAGGCAGACAGACAGACATGTCTTTGAGACTGAATCTCTGCCAGCCTCAAACCAATCCAGTGGGAGAAAGCCTGTAAGGTACTGCAGCCGGGTGGAGATTCCTTCCGGGCAGGTATCTCGGCAGAAAGAGGTTTTCCAGGCCCTGGAGGCGGGCAAGAAGGAGGTCCCGGAGACCACAATCAACCTGGGGTCCATCCCCACAGGCTCTGTGCATAAATTCACCTGGCTCTTTGAAAACTGTCCCATGGGCTCCCTGGCAGCTGAGAGCATCAGAGGGGACAACCTCCAGGAAGAACAGCCAAAAGGCTCTGCAGGCCATGGGACACCAGAGAGGCAGGAGACAGCAGCCGAGAGAACCCTTCGGACTTTGCATGCCACCCCCGGCATCCTGCACCATGGAGGCATCCTCATGGAGGCCCGAGGGCCAGGGGAGCTCTGTCTTGCCAAGTATGTGCTCCCAAGCCCAGGGCAGGGGCGCCCCTACATACGGAAGGAGGAGCTGGTGTGTGGTGAGCTTCCCAGGATCGTCCGTCAAGTGCTGCGCCGGACAGACGTGGACCAGCAGGGACTGCTGGTTCAGGAGGACACAGCTGGGCAGCTCCAGCTCCACCCACTCACGCTGCCAGGGCCTGGTGACCCTGGGAATATTGAAGACATGGACCCTGAGCTCCAGCAGCTGCTGGCCTGTGGCCTGGGAGTCTCTGTGTCAAAGACGGGGCTGGTGATGCAAGAGACAGGACAGGGCCTAGTGGCACTGACTGCCTACTCCCTCCAGCCCCAGCTTACCAGCAGGGCCCCTGAAAGAAGCAGTGTGCAGCTGCTGGCCAGCTGCATAGACAAAGGAGACCTGCACAGCCTTCACAGTTTGCGGTGGGAGCCGCCAACAGACCCAAGTTCTGGACCTGCTACTGAGGAGTCCCAGAGGGTCCCCCAAACTGAGAGCATCATACATGTTACCCCATTAGACTCCACCATGGAGATGGGGCAGCTGAGAATCTCAGGATCCACACCCTGCCCACCTCCATCTCGGGCAGCTGGAAAAGTGGTCCTTCCAAATGGGAAACCTGTAGCCCAAGCTCCATTGCAGGAAGCAAGGAAGAAAACGGATATCAGCCATGCTGGGCAGAAAGGGAAGGCAGCCTCAGGAAGACCAGAAGGAACCATTGCTTCCCCTCTAGGGTCTGGGGCTCCAGATCTCCAGGAAGCCATGCAGAATCTGCGTTTGGCAACCGCTGAGGCCCAAAGCCTGCACCAGCAGGTTCTGAGCAGGCATCCACAGGGCTCTGACCCTGTAGCCACCTCCATGCCTGTCCAAGATGTTCTGCAAGCATCCACTCCTGCCACTGGGGTTACTCAAGGCAGCATCAGGCCTGTGGCTGGAAGTGAAGCCAGGATCCCAGCATTCCCCAGAAAG
Seq C2 exon
CTGCTGTGACAGAAGATCCTGACCACCCAACTCAAGGCCACCACCAGGAGGACTCCATCCAGCAGGCCCCGGAGCCCCTGCAGGAACCCCTTCTTCATATTCACAACAGACCTTCTGGCCAGAAAACCCCTGAAGGGTCAGAGACAAAACCCTCCAAAGCGGAATCCACCATGCTTCCAAGAAAGAAACCCCCAGTGCCTCCCAAACCTGCACATCTAAGCCAAATCCACCCACCTCAGAGGCTGCCCAAGCCCTTAGCAGGCTCTGCCAGAGCCTCAGAAGCAGGACAAGACCATAAGCCAGGTGAGCCAGGTATAGCCAACCCAGGGTCAGACAAAGCTCCCACAATAGCAGGCCAGGACTGCCTGCCTCTGGCTGAAAGCTCCAAGGGCCAGAAGCAACCTGCTCATCAGCGTCCACTCAGCTCTATGGCTTCCAGGCCTAGCAGGGGTCAGATAACCAGCAGCAACAGCCAGAGCCCCGAGTCTCCTAAGTTGAAC
VastDB Features
Vast-tools module Information
Secondary ID
ENSMUSG00000079243-'0-1,'0-0,1-1=AN
Average complexity
A_S
Mappability confidence:
100%=100=100%
Protein Impact





	

	
ORF disruption upon sequence exclusion (Ref, Alt. ATG (<=10 exons))





No structure available

		

			
Features


			

				
Disorder rate (Iupred):
  C1=NA A=0.675 C2=0.000
 
                        

				
Domain overlap (PFAM):

					





						

							
C1:
NA

							
A:
PF080437=Xin=WD(100=1.4),PF080437=Xin=WD(100=1.4),PF080437=Xin=WD(100=1.4),PF080437=Xin=WD(100=1.4),PF080437=Xin=WD(100=1.3),PF080437=Xin=WD(100=1.4),PF080437=Xin=WD(100=1.4),PF080437=Xin=WD(100=1.4),PF080437=Xin=WD(100=1.4),PF080437=Xin=WD(100=1.4),PF080437=Xin=WD(100=1.4),PF080437=Xin=WD(100=1.4),PF080437=Xin=WD(100=1.4),PF080437=Xin=WD(100=1.4)

							
C2:
NO

						

					

				








    
Main Inclusion Isoform:
ENSMUSP00000107262





     
                   









    
Main Skipping Isoform:
NA





     
      









    
Other Inclusion Isoforms:
NA
          









    
Other Skipping Isoforms:
NA
  



Associated events







Other assemblies


mm10




Conservation


Human
(hg38)
chr3:39186089-39189525 
ALTERNATIVE
HsaEX6055242
(XIRP1)
Human
(hg19)
chr3:39227580-39231016 
ALTERNATIVE
HsaEX6055242
(XIRP1)
Rat
(rn6)
chr8:128704895-128708273 
HIGH PSI
RnoEX0099944
(Xirp1)
Cow
(bosTau6)
chr22:12552463-12555808 
Chicken
(galGal4)
chr2:4948021-4952730 
ALTERNATIVE
GgaEX1064422
(XIRP1)
Chicken
(galGal3)
chr2:4878837-4883550 
Zebrafish
(danRer10)
No conservation detected
Fruitfly
(dm6)
No conservation detected




Primers PCR

	

		

			
Suggestions for RT-PCR validation

			

				
F: 
No suggested primer sequences

				
R: 
No suggested primer sequences

				
Band lengths: 

			

		

	





	
Functional annotations
(Submit an annotation)

	


There are 1 annotated functions for this event 


PMID: 16631741
HsaEX6055242
Encodes an experimentally validated Eukaryotic Linear Motif (ELM). Method: colocalization, far western blotting, mutation analysis, peptide array, two hybrid. ELM ID: ELMI002581; ELM sequence: LPLPP; Overlap: FULL


		










GENOMIC CONTEXT[edit]












INCLUSION PATTERN[edit]










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