Special

RnoEX0099944 @ rn6

Exon Skipping

Gene
ENSRNOG00000037085 | Xirp1
Description
xin actin-binding repeat containing 1 [Source:NCBI gene;Acc:100910104]
Coordinates
chr8:128702133-128711221:-
Coord C1 exon
chr8:128710958-128711221
Coord A exon
chr8:128704895-128708273
Coord C2 exon
chr8:128702133-128704506
Length
3379 bp
Sequences
Splice sites
3' ss Seq
GCTTCTCCCCTCCTTCCCAGAAG
3' ss Score
8.27
5' ss Seq
AAGGTCAGT
5' ss Score
8.68
Exon sequences
Seq C1 exon
GTGCACAAAGCCCTGGGTTCACCACATAAAACCAGAAATGGCGTTTCGTGTTGCATGCTTGTAATCTGTCTGGGGGGTGGGGGGTGGAGGCAGGAGGGTCTAGAGTTCAAGGTCATCCTCAACTACTTACGGAGTTCAAGGCCAACCTGGACTGGATGAGAATCTGTCTGAAAAATAAATAAAAAGGCTGATGTGGCTCCTCTTGCTGCAGGGCTTCCTCTCAAGAAACCTGAGATCTCGGGAAAGAGAGAAGAGAGGCAGAAG
Seq A exon
AAGGATGGCCGATGCCCAGATGCAGGTAGTTCATACACCAACCATCCAAATGAGGACTGGAGAGGACCTGCCCCTTCCCCCTCCCTCAGCCCTAGAGGGTCTGCCGCCACCGCCCCCCAAAGAATCTTTCTCCAAGTTCCAGCAGCAGCGGCAAGCCAACGAGCTTCGCCGTCTCTACAAACACATCCACCCTGAGCTTCGGAAGAACCTCGAGGAGGCTGTAGCCGAGGACCTGGCCAAGGTACTCGGTTCGGAGGAGCCCACCGAGGGCGATGTGCAATGTATGCGCTGGATCTTTGAGAACTGGAGTTTGGATGCCATTGGCGACCACGAGAGGCCAGCTGGCAAGGAGCCTGTGTCAGGTGGCAACGTTCAGGCCACCTCTCGGAAGTTTGAGGAAGGCTCCTTTACCAACAGCTCAGATCTGGAGCCAGGACCCCAGCTGTCAGGGGGTGACGTCCGAGCTACCAGACAGCTGTTTGAGACCAAGTCACTGGATGCACTGACAGGCCAGGAAGAGGCAACACAGATGACCATGAAGGAACCTGCAGTCTCTGGAGATGTACAGGGAACCAGAAAACTCTTTGAGACTAAGCCCCTCGACATGCTGGGCTCCTGCCCCTCTATCCAGGACCAGAGCCCTTTAGAGCTGCGCTCAGAGATTCAGGAGCTGAAGGGTGATGTGAAGAAGACGGTGAAGCTGTTTCAGACGGAGCCTCTATGTGCCATCCAGGATGCAGAGGGCGCCATCCATGAAGTCAAGGCTGCCTGTCGGGAGGAGATCCAGAGCAATGCAGTGAGGTCAGCTCGCTGGCTCTTTGAGACCCGACCTCTGGACGCCTTCAACCAGGACCCCAGCCAGGTGAGGGTGATTCGGGGGATCTCCCTCGAGGAGGGAGCCCTGCCCGACGTCAGTGCAACTCGCTGGATCTTCGAGACGCAGCCTCTGGATGCCATTCGTGAGATCTTGGTGGACGAGAAGGACTTCCAGCCATCTCCAGATCTCATCCCTCCTGGTCCAGACGTTCAGCATCAGCGACATCTGTTTGAGACCTGCGCCCTGGACACTCTGAAGGGAGAAAGAGAAACCGAGGCAGAGGCTCCAGCCAAGGAGGAGGTGATTCCTGGTGACGTCCGCTCTACACTCTGGCTGTTTGAAACAAAACCCCTGGATGCTTTCAGAGACCAGGTCCAAGTGGGTCACCTGCAACGGGTGGATCACCAGAAGGGTGAGGGGCCTGTGATAGAGTGTCTGTCCAGTAACGGCACTTCAGCGCTGCCTCTGTCTCAGGGTGTCCCCCAGAACAATGGGCCGAAAGGGGATGTGAAAACCTTCAAGAATCTTTTTGAGACCCTTCCCTTAGACAGCATTGGGCAGGGTGAGCCTTCAGCCTGTGGAAACATAAACAGAGGACAAAGGACTGATTCTACTGGGCTGTCCGAGGGCGCCGATGCCCCCGTATATGCTATGCAGGACAGCAGAGGACAGCTTCATGCCCTGACTTCTGTCAGCAGAGAGCAGGTAGTTGGAGGTGATGTACAAGGCTACAAGTGGATGTTTGAGACACAGCCCCTGGACCGGCTGGGCAGAAGCCCCAGTACCGTGGATGTGGTGCGAGGCATCACCCGGCAAGAAGTGGTGGCTGGGGATGTAGGCACCACTCGGTGGCTCTTTGAGACGCAACCACTGGAGATGATCCACCAACAAGAGCAGCAGAAGCGAGAGGAGGAGGAGGGGAGGGGTCCAGGAGGCCCCCCTCCTGAGCTCCCCCAGAAGGGCGATGTACAAACCATCCGCTGGCTATTTGAGACCTACCCTATGAGCGAGTTGGCAGAGAAGCAGGAATCTGAGGTCACAGGCCCTGTGAGCAAGGCAGAGGCACAGTCATGCACCTGGATGTTTGGGTCCCAATCTCTGAACCAGGCAGAGGGCTCTGGGGAGCAGCACTTGCAAACCAGCCAGGTCCAGGCTGGAGACAGACAGACAGACAGCCATGTCTTTGAGACTGAATCTCTGTCAGCCCAGGGCCAGTCCAGTGGGAGAAAGCCTGTAAGGTACTGCAGCCGAGTGGAGATTCCTTCCGGGCAGGTATCTCGGCAGAAAGAAGTTTTCCAAGCCCTGGAAGCAGGCAAGAGGGGGGTACAGGAGACTGTTTTAAGCCCCGGATCCATCCCCACAGGCTCCGTGCATAAATTCACCTGGCTCTTTGAAAACTGCCCCATGGGCTCCCTGGCAGCAGAGAGTGTCAGTGGGGGCAACCTCCAGGAAGAACAGCCCAAAGTCTCTGCAGACCCTGGGACCCCAGAGAGGCAGGAGACAGCAGCCGAGAGAACCCTTCGGACTTTGCATGCCACCCCTGGCATCCTGCACCACGGAGGGATCCTCATGGAAGCCCGAGGGCCAGGGGAGCTCTGCCTTGCCAAGTATGTGCTCCCAAGCCCAGGGCAGGGGCGCCCCTGTGTACAGAAGGAGGAGCTGGTGTGCGGTGAGCTCCCCAGGATCGTCCGTCAAGTGCTGGGCCGGACAGATGTGGACCAGCAGGGACTGCTGGTTCAGGAGGACACAGCTGGCCAACTCCGACTCCACCCACTCAAACTGCCAGGGCCTGGTGACCCTGAGAATATTGAAGACATGGACCCGGAGCTCCAGCAGCTGCTGGCCTGTGGCCTGGGAGTCTCTATGGCAAAGACGGGGCTGGTGATGCAAGAAACAGGACAGGGCCTAGTGGCATTGACTGCCTACTCCCTCCAGCCCCAGCCAACCAGCAGGGGCCCTGAAAGAAGCAGTGTGCAGCTGCTGGCCAGCTGCATAGACAAAGGAGAACTGCACAGCCTTCCCAGTTTGCGGTGGGAGCCGCCAACAGACTCAAGTTCAGTACCAGTTACTGAGGAGACCCAGAGGCTTCCCCCAACTGAGAGCATCATACGCGTCACCCCATTAGACTCCACCATGAAGATGGGGCATCTGAGAGTCTCAGGATCCACACCCTGCCCACCTCTACCTCGGGCAGCTGGAAAAGTGGTCCTTCCAAATGGGAGACCGGGAGCACCATTGCAGGAAGCAAGGAAGCAAGTGGATATCAGCCATGCTGGGCAGAAAGGGAAGGCAGCCTCAGGAAGACCAGAAGGAACCATTGCTCCTCCTTTAGGGTCTGGGGCTCCAAATCTCCAGGAGGCCATGCAAAATCTGCGTTTGGCAACTGCTGAGGCCCAAAGCCTGCACCAGCAGGTTCTGAGCAGGCATGCACAGGGCTCTGACCCTGCAGCCACCTCCATATCTGCTCAAGATGTTCTGCAAGTGCCGACTCCTACCACTACCCAAGGTAGCATCATGCCTGTGGCTGGAAGGGACGCCAGGATCACAGCGGTCCCCAGAAAG
Seq C2 exon
CTGCTGTGACAGAAGAACCAGACCACCCAGCTCAAGGCCACCACCAGAAGGACTCCGTCCAGCAGGCCTCCAAGCCCCTGCGGGAACCCCTTCTTCACAGTCACAACAGACCTGCTGGCCAGAAAACCCTTGAAGGGTCAGAGACAAAGCTCTCTAAAGCGGAATCCACTGTGCTTCCAAGAAAGAAACCCCCAGTGCCTCCGAAACCTGCCCATCTAAGCCAAGTCCACCCACCTCATAGGCTGCCCAAGCCCTTAGCAGCCTCTGCCAGCATCTCAGAAGCAGGACAAGACCATAAGCCAGGTGAGCCAGGTGTAGCCAACCCTGGGTCGGCCAAAGCTCCCACAATAGCAGGTCAGGGCTGCCTGCCCCTGGCTGAGTGCTCCAAGGGGCAGAAACAGCCTATGCGCCAGTATCCACTCAGCACCACAGCTTCCAGACCTAGCGGGGGCCAAACAAGCAACAGCAACAGCCAGAGCCCTGAGTCTCGCAAGTTGACC
VastDB Features
Vast-tools module Information
Secondary ID
ENSRNOG00000037085_CASSETTE1
Average complexity
S
Mappability confidence:
100%=100=100%
Protein Impact





	

	
ORF disruption upon sequence exclusion





No structure available

		

			
Features


			

				
Disorder rate (Iupred):
  C1=0.280 A=0.634 C2=0.000
 
                        

				
Domain overlap (PFAM):

					





						

							
C1:
NO

							
A:
PF080437=Xin=WD(100=1.4),PF080437=Xin=WD(100=1.4),PF080437=Xin=WD(100=1.4),PF080437=Xin=WD(100=1.4),PF080437=Xin=WD(100=1.3),PF080437=Xin=WD(100=1.4),PF080437=Xin=WD(100=1.4),PF080437=Xin=WD(100=1.4),PF080437=Xin=WD(100=1.4),PF080437=Xin=WD(100=1.4),PF080437=Xin=WD(100=1.4),PF080437=Xin=WD(100=1.4),PF080437=Xin=WD(100=1.4)

							
C2:
NO

						

					

				








    
Main Inclusion Isoform:
ENSRNOP00000052739





     
                   









    
Main Skipping Isoform:
ENSRNOT00000055888fB16646





     
      









    
Other Inclusion Isoforms:
NA
          









    
Other Skipping Isoforms:
NA
  



Associated events







Conservation


Human
(hg38)
chr3:39186089-39189525 
ALTERNATIVE
HsaEX6055242
(XIRP1)
Human
(hg19)
chr3:39227580-39231016 
ALTERNATIVE
HsaEX6055242
(XIRP1)
Mouse
(mm10)
chr9:120016426-120019819 
HIGH PSI
MmuEX6069879
(Xirp1)
Mouse
(mm9)
chr9:119925544-119928937 
HIGH PSI
MmuEX6069879
(Xirp1)
Cow
(bosTau6)
chr22:12552463-12555808 
Chicken
(galGal4)
chr2:4948021-4952730 
ALTERNATIVE
GgaEX1064422
(XIRP1)
Chicken
(galGal3)
No conservation detected
Zebrafish
(danRer10)
chr6:9945552-9945931 
Fruitfly
(dm6)
No conservation detected




Primers PCR

	

		

			
Suggestions for RT-PCR validation

			

				
F: 
No suggested primer sequences

				
R: 
No suggested primer sequences

				
Band lengths: 

			

		

	





	
Functional annotations
(Submit an annotation)

	


There are 1 annotated functions for this event 


PMID: 16631741
HsaEX6055242
Encodes an experimentally validated Eukaryotic Linear Motif (ELM). Method: colocalization, far western blotting, mutation analysis, peptide array, two hybrid. ELM ID: ELMI002581; ELM sequence: LPLPP; Overlap: FULL


		










GENOMIC CONTEXT[edit]












INCLUSION PATTERN[edit]











Retrieved from "https://vastdb.crg.eu/wiki/Special:VastDB"