MmuEX6086271 @ mm9

Exon Skipping

Gene

ENSMUSG00000033196 | Myh2

Description

myosin, heavy polypeptide 2, skeletal muscle, adult [Source:MGI Symbol;Acc:MGI:1339710]

Coordinates

chr11:67002821-67004968:+

Coord C1 exon

chr11:67002821-67003210

Coord A exon

chr11:67003809-67003935

Coord C2 exon

chr11:67004850-67004968

Length

127 bp

Sequences

Splice sites

3' ss Seq

TCTCTCTCTCTCTCTCTTAGGGA

3' ss Score

12.92

5' ss Seq

CCGGTAATT

5' ss Score

6.28

Exon sequences

Seq C1 exon

GCCCGCATCGAGGAGCTGGAGGAGGAAATCGAGGCAGAGCGGGCCTCCAGGGCCAAAGCAGAGAAGCAGCGCTCTGACCTCTCCCGGGAACTGGAGGAGATCAGCGAGAGGCTGGAAGAAGCCGGCGGAGCCACTTCAGCCCAGATCGAGATGAACAAGAAGAGAGAGGCTGAGTTCCAGAAAATGCGCAGGGACCTGGAGGAGGCCACGCTGCAGCATGAAGCCACAGCAGCCACCCTGAGGAAGAAGCATGCGGACAGCGTGGCCGAGCTCGGGGAGCAGATCGACAACCTGCAGCGGGTGAAGCAGAAGCTGGAGAAGGAGAAGAGCGAGATGAAGATGGAGATCGATGATCTTGCCAGTAATGTAGAGACAGTGTCTAAGGCCAAG

Seq A exon

GGAAACCTCGAGAAGATGTGCCGCACCCTGGAGGACCAGGTGAGTGAGCTGAAGTCAAAGGAGGAGGAACAGCAGCGACTGATCAACGACCTGACAACCCAGAGAGGACGACTGCAGACCGAATCCG

Seq C2 exon

GTGAATTTTCCAGGCAGCTTGATGAGAAGGAAGCGCTGGTATCTCAGTTATCAAGGGGGAAGCAAGCATTCACTCAACAGATTGAGGAGCTAAAGAGGCAGCTTGAAGAGGAAGTAAAG

VastDB Features

Vast-tools module Information

Secondary ID

ENSMUSG00000033196-'27-28,'27-27,28-28=AN

Average complexity

A_S

Mappability confidence:

100%=100=100%

Protein Impact

ORF disruption upon sequence exclusion

No structure available

Features

Disorder rate (Iupred):

C1=0.908 A=0.977 C2=0.138

Domain overlap (PFAM):

C1:

PF0003816=Filament=FE(45.1=100),PF0157614=Myosin_tail_1=FE(50.0=100),PF045827=Reo_sigmaC=PU(29.8=32.3)

A:

PF135141=AAA_27=FE(5.7=100),PF0003816=Filament=FE(14.8=100),PF0157614=Myosin_tail_1=FE(8.2=100),PF0003816=Filament=PU(25.5=55.8)

C2:

PF0003816=Filament=PD(5.2=37.5),PF0157614=Myosin_tail_1=FE(15.1=100),PF045827=Reo_sigmaC=FE(27.7=100),PF0003816=Filament=PU(13.2=87.5),PF0157614=Myosin_tail_1=PU(0.7=10.0)

Main Inclusion Isoform:

ENSMUSP00000018641