MmuEX6101040 @ mm10
Exon Skipping
Gene
ENSMUSG00000049252 | Lrp1b
Description
low density lipoprotein-related protein 1B (deleted in tumors) [Source:MGI Symbol;Acc:MGI:2151136]
Coordinates
chr2:41188813-41246089:-
Coord C1 exon
chr2:41245940-41246089
Coord A exon
chr2:41193538-41193678
Coord C2 exon
chr2:41188813-41188938
Length
141 bp
Sequences
Splice sites
3' ss Seq
AAAATCTCTTTTCTATACAGATA
3' ss Score
8.67
5' ss Seq
AAGGTATGT
5' ss Score
9.79
Exon sequences
Seq C1 exon
GTCTATCGATAGACTATGTGGAGAATAAGCTTTATTGGATCAGTTCTGGAAATGGAACCATAAACCGATGCAACCTAGATGGTGGTAATTTAGAAGTAATAGAGTCAATGAAGGAAGAATTAACAAAAGCTACAGCCTTAACCATCATGG
Seq A exon
ATAAGAAACTCTGGTGGGCAGATCAAAACTTAGCTCAACTGGGAACTTGTAACAAAAGAGATGGAAGAAATCCCAGCATTCTGCGAAATAAGACTTCCGGAGTTGTTCACATGAAAGTGTATGACAAAGAAGCACAACAAG
Seq C2 exon
GCAGCAATTCTTGCCAAGTAAACAATGGTGGGTGTTCTCAGCTTTGCTTACCAACATCGGAAACAACCAGGACTTGCATGTGTACAGTGGGATATTATCTCCAGAAGAACCGCATGTCATGCCAAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSMUSG00000049252-'56-52,'56-50,57-52
Average complexity
C2
Mappability confidence:
100%=100=100%
Protein Impact
Alternative protein isoforms (Ref)
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=0.042 C2=0.000
Domain overlap (PFAM):
C1:
PF0005812=Ldl_recept_b=PD(10.8=7.8)
A:
NO
C2:
PF146701=FXa_inhibition=WD(100=86.0)
Main Skipping Isoform:
NA
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
AGCTTTATTGGATCAGTTCTGGA
R:
TGACATGCGGTTCTTCTGGAG
Band lengths:
242-383
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Ribosome-engaged transcriptomes of neuronal types
- Neural differentiation time course
- Muscular differentiation time course
- Spermatogenesis cell types
- Reprogramming of fibroblasts to iPSCs
- Hematopoietic precursors and cell types