HsaEX6015741 @ hg38
Exon Skipping
Gene
ENSG00000168702 | LRP1B
Description
LDL receptor related protein 1B [Source:HGNC Symbol;Acc:HGNC:6693]
Coordinates
chr2:140769213-140813806:-
Coord C1 exon
chr2:140813657-140813806
Coord A exon
chr2:140776098-140776238
Coord C2 exon
chr2:140769213-140769344
Length
141 bp
Sequences
Splice sites
3' ss Seq
AATATCTTTCCTTTTTCTAGATA
3' ss Score
9.63
5' ss Seq
AAGGTAAAT
5' ss Score
8.88
Exon sequences
Seq C1 exon
GTCTATCGATAGACTATGTGGAAAACAAGCTTTATTGGATCAGTTCAGGGAATGGAACCATAAATAGATGCAACCTGGATGGTGGTAATTTAGAAGTAATCGAGTCAATGAAAGAAGAATTAACAAAAGCTACAGCCCTAACCATCATGG
Seq A exon
ATAAGAAACTGTGGTGGGCAGACCAAAACTTAGCCCAGCTAGGAACCTGCAGCAAAAGAGACGGAAGAAACCCCACCATCCTACGGAATAAGACTTCTGGGGTAGTTCATATGAAAGTCTATGATAAAGAAGCACAGCAAG
Seq C2 exon
GTATAGAATCATTTCTTATGTACTCTGTTCATGAAGGAATCAGGGGAATACCTCTTGAACCAAGTGACAAAATGGATGCTTTGATGCCTATATCAGGAACTTCATTTGCCGTGGGAATAGATTTCCATGCAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000168702_MULTIEX3-12/13=10-C2
Average complexity
C2
Mappability confidence:
100%=100=100%
Protein Impact
Alternative protein isoforms (Ref)
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=0.042 C2=0.000
Domain overlap (PFAM):
C1:
PF0005812=Ldl_recept_b=PD(10.8=7.8)
A:
NO
C2:
NO
Main Skipping Isoform:
ENST00000389484fB19033
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Cow
(bosTau6)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
ACAAGCTTTATTGGATCAGTTCAGG
R:
TCCCACGGCAAATGAAGTTCC
Band lengths:
242-383
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains