HsaEX6015739 @ hg38
Exon Skipping
Gene
ENSG00000168702 | LRP1B
Description
LDL receptor related protein 1B [Source:HGNC Symbol;Acc:HGNC:6693]
Coordinates
chr2:140769213-140841092:-
Coord C1 exon
chr2:140840918-140841092
Coord A exon
chr2:140839991-140840085
Coord C2 exon
chr2:140769213-140769344
Length
95 bp
Sequences
Splice sites
3' ss Seq
CATATGTCTTTTGAATTAAGAAA
3' ss Score
1.9
5' ss Seq
TTGGTAAGT
5' ss Score
10.47
Exon sequences
Seq C1 exon
ATATTCAGAGTATCAGAGGGCTAGCAGTGGATTGGGTGTCACGTAATTTATACTGGATTAGCTCAGAATTTGATGAAACGCAAATTAATGTGGCAAGGCTAGATGGCTCTTTGAAAACCTCAATTATCCATGGAATCGATAAGCCACAGTGTCTTGCAGCTCACCCAGTCAGGGG
Seq A exon
AAAACTCTACTGGACCGATGGAAACACAATTAACATGGCAAATATGGATGGCAGTAATAGCAAGATTCTGTTTCAGAATCAGAAGGAGCCAGTTG
Seq C2 exon
GTATAGAATCATTTCTTATGTACTCTGTTCATGAAGGAATCAGGGGAATACCTCTTGAACCAAGTGACAAAATGGATGCTTTGATGCCTATATCAGGAACTTCATTTGCCGTGGGAATAGATTTCCATGCAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000168702_MULTIEX3-9/13=8-C2
Average complexity
C3
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence exclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=0.000 C2=0.000
Domain overlap (PFAM):
C1:
PF0005812=Ldl_recept_b=PD(26.8=18.6),PF0005812=Ldl_recept_b=PU(0.1=0.0)
A:
PF0005812=Ldl_recept_b=PU(86.5=97.0)
C2:
NO
Main Skipping Isoform:
NA
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Cow
(bosTau6)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
AATGTGGCAAGGCTAGATGGC
R:
GGCATCAAAGCATCCATTTTGTCA
Band lengths:
177-272
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains