HsaEX6015739 @ hg19
Exon Skipping
Gene
ENSG00000168702 | LRP1B
Description
low density lipoprotein receptor-related protein 1B [Source:HGNC Symbol;Acc:6693]
Coordinates
chr2:141571226-141598661:-
Coord C1 exon
chr2:141598487-141598661
Coord A exon
chr2:141597560-141597654
Coord C2 exon
chr2:141571226-141571375
Length
95 bp
Sequences
Splice sites
3' ss Seq
CATATGTCTTTTGAATTAAGAAA
3' ss Score
1.9
5' ss Seq
TTGGTAAGT
5' ss Score
10.47
Exon sequences
Seq C1 exon
ATATTCAGAGTATCAGAGGGCTAGCAGTGGATTGGGTGTCACGTAATTTATACTGGATTAGCTCAGAATTTGATGAAACGCAAATTAATGTGGCAAGGCTAGATGGCTCTTTGAAAACCTCAATTATCCATGGAATCGATAAGCCACAGTGTCTTGCAGCTCACCCAGTCAGGGG
Seq A exon
AAAACTCTACTGGACCGATGGAAACACAATTAACATGGCAAATATGGATGGCAGTAATAGCAAGATTCTGTTTCAGAATCAGAAGGAGCCAGTTG
Seq C2 exon
GTCTATCGATAGACTATGTGGAAAACAAGCTTTATTGGATCAGTTCAGGGAATGGAACCATAAATAGATGCAACCTGGATGGTGGTAATTTAGAAGTAATCGAGTCAATGAAAGAAGAATTAACAAAAGCTACAGCCCTAACCATCATGG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000168702-'31-31,'31-30,32-31=AN
Average complexity
A_S
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence exclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=0.000 C2=0.000
Domain overlap (PFAM):
C1:
PF0005812=Ldl_recept_b=PD(26.8=18.6),PF0005812=Ldl_recept_b=PU(0.1=0.0)
A:
PF0005812=Ldl_recept_b=PU(86.5=97.0)
C2:
PF0005812=Ldl_recept_b=PD(10.8=7.8)
Main Skipping Isoform:
NA
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
CACAGTGTCTTGCAGCTCACC
R:
CCATGATGGTTAGGGCTGTAGC
Band lengths:
181-276
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)