MmuEX6101038 @ mm10
Exon Skipping
Gene
ENSMUSG00000049252 | Lrp1b
Description
low density lipoprotein-related protein 1B (deleted in tumors) [Source:MGI Symbol;Acc:MGI:2151136]
Coordinates
chr2:41245940-41269329:-
Coord C1 exon
chr2:41269155-41269329
Coord A exon
chr2:41268337-41268431
Coord C2 exon
chr2:41245940-41246089
Length
95 bp
Sequences
Splice sites
3' ss Seq
TCCATATATTTTGAATTAAGGAA
3' ss Score
3.61
5' ss Seq
TTGGTAAGT
5' ss Score
10.47
Exon sequences
Seq C1 exon
ATATTCAGAGTATCAGAGGGTTAGCAGTGGACTGGGTTTCACGTAATTTATACTGGATTAGCTCAGAATTCGATGAAACACAAATTAATGTGGCAAGATTAGATGGCTCTTTGAAAACCTCAATTATTCACGGAATCGATAAACCGCAGTGTCTGGCAGCCCACCCAGTCAGAGG
Seq A exon
GAAACTGTACTGGACAGATGGAAATACAATAAACATGGCAAATATGGATGGAAGTAACAGCAAGATTCTCTTTCAGAACCAAAAGGAACCAGTTG
Seq C2 exon
GTCTATCGATAGACTATGTGGAGAATAAGCTTTATTGGATCAGTTCTGGAAATGGAACCATAAACCGATGCAACCTAGATGGTGGTAATTTAGAAGTAATAGAGTCAATGAAGGAAGAATTAACAAAAGCTACAGCCTTAACCATCATGG
VastDB Features
Vast-tools module Information
Secondary ID
ENSMUSG00000049252-'53-47,'53-46,54-47=AN
Average complexity
A_S
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence exclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=0.000 C2=0.000
Domain overlap (PFAM):
C1:
PF0005812=Ldl_recept_b=PD(26.8=18.6),PF0005812=Ldl_recept_b=PU(0.1=0.0)
A:
PF0005812=Ldl_recept_b=PU(86.5=97.0)
C2:
PF0005812=Ldl_recept_b=PD(10.8=7.8)
Main Skipping Isoform:
NA
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
ATAAACCGCAGTGTCTGGCAG
R:
TGGTTAAGGCTGTAGCTTTTGT
Band lengths:
181-276
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Ribosome-engaged transcriptomes of neuronal types
- Neural differentiation time course
- Muscular differentiation time course
- Spermatogenesis cell types
- Reprogramming of fibroblasts to iPSCs
- Hematopoietic precursors and cell types