HsaEX6015738 @ hg38
Exon Skipping
Gene
ENSG00000168702 | LRP1B
Description
LDL receptor related protein 1B [Source:HGNC Symbol;Acc:HGNC:6693]
Coordinates
chr2:140769213-140851783:-
Coord C1 exon
chr2:140851652-140851783
Coord A exon
chr2:140850102-140850329
Coord C2 exon
chr2:140769213-140769344
Length
228 bp
Sequences
Splice sites
3' ss Seq
AATTTCTATTTCTTTTTTAGAAA
3' ss Score
9.45
5' ss Seq
GAGGTAAAA
5' ss Score
7.3
Exon sequences
Seq C1 exon
CTCCCAATCCTTGTGCAGCTAATGATGGCAAAGGCCCCTGCTCTCACATGTGTCTAATCAATCACAATAGGAGTGCTGCCTGTGCGTGCCCCCACTTGATGAAGCTTTCTTCAGACAAGAAGACCTGCTATG
Seq A exon
AAATGAAAAAATTTCTTCTTTATGCAAGACGTTCTGAAATCAGAGGAGTGGATATTGACAATCCATACTTTAACTTCATCACGGCATTTACAGTCCCTGATATTGATGACGTTACTGTGATAGACTTCGATGCATCTGAGGAACGTTTATACTGGACAGATATTAAAACACAAACCATTAAACGAGCTTTTATTAACGGAACTGGGTTAGAAACTGTTATTTCAAGAG
Seq C2 exon
GTATAGAATCATTTCTTATGTACTCTGTTCATGAAGGAATCAGGGGAATACCTCTTGAACCAAGTGACAAAATGGATGCTTTGATGCCTATATCAGGAACTTCATTTGCCGTGGGAATAGATTTCCATGCAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000168702_MULTIEX3-7/13=6-C2
Average complexity
C3
Mappability confidence:
100%=100=100%
Protein Impact
Alternative protein isoforms (Ref)
No structure available
Features
Disorder rate (Iupred):
C1=0.156 A=0.000 C2=0.000
Domain overlap (PFAM):
C1:
PF146701=FXa_inhibition=WD(100=86.7)
A:
PF0005812=Ldl_recept_b=PU(70.7=37.7)
C2:
NO
Main Skipping Isoform:
NA
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Cow
(bosTau6)
No conservation detected
Chicken
(galGal3)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
CTCCCAATCCTTGTGCAGCTA
R:
TCTATTCCCACGGCAAATGAAGT
Band lengths:
253-481
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains