MmuEX6101036 @ mm10
Exon Skipping
Gene
ENSMUSG00000049252 | Lrp1b
Description
low density lipoprotein-related protein 1B (deleted in tumors) [Source:MGI Symbol;Acc:MGI:2151136]
Coordinates
chr2:41269155-41284226:-
Coord C1 exon
chr2:41284095-41284226
Coord A exon
chr2:41282037-41282264
Coord C2 exon
chr2:41269155-41269329
Length
228 bp
Sequences
Splice sites
3' ss Seq
ACTTTAATTCCTTTTTCCAGAAA
3' ss Score
9.16
5' ss Seq
GAGGTAAAG
5' ss Score
8.27
Exon sequences
Seq C1 exon
CTCCCAACCCTTGTGCAGCCAATGAAGGTAGAGGCCCCTGCTCTCACCTGTGCCTCATCAATCATAATAGGAGTGCAGCTTGTGCCTGCCCCCACCTAATGAAGCTTTCCTCTGACAAGAAAACCTGCTATG
Seq A exon
AAATGAAAAAATTTCTTCTTTATGCAAGACGTTCTGAGATCCGAGGGGTGGACATTGACAATCCCTATGTGAACTTCATCACAGCCTTCACTGTCCCAGATATTGACGATGTTGCTGTAATAGACTTCGATGCCTCTGAAGAGCGTTTGTACTGGACAGACATCAAAACACAAACCATTACACGGGCTTTCATTAACGGGACGGGACTAGAGACAGTTATTTCAAGAG
Seq C2 exon
ATATTCAGAGTATCAGAGGGTTAGCAGTGGACTGGGTTTCACGTAATTTATACTGGATTAGCTCAGAATTCGATGAAACACAAATTAATGTGGCAAGATTAGATGGCTCTTTGAAAACCTCAATTATTCACGGAATCGATAAACCGCAGTGTCTGGCAGCCCACCCAGTCAGAGG
VastDB Features
Vast-tools module Information
Secondary ID
ENSMUSG00000049252-'50-45,'50-44,52-45=AN
Average complexity
A_S
Mappability confidence:
100%=100=100%
Protein Impact
Alternative protein isoforms (Ref)
No structure available
Features
Disorder rate (Iupred):
C1=0.156 A=0.000 C2=0.000
Domain overlap (PFAM):
C1:
PF146701=FXa_inhibition=WD(100=86.7)
A:
PF0005812=Ldl_recept_b=PU(70.7=37.7)
C2:
PF0005812=Ldl_recept_b=PD(26.8=18.6),PF0005812=Ldl_recept_b=PU(0.1=0.0)
Main Skipping Isoform:
NA
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Chicken
(galGal3)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
AACCCTTGTGCAGCCAATGAA
R:
CCTCTGACTGGGTGGGCTG
Band lengths:
302-530
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Ribosome-engaged transcriptomes of neuronal types
- Neural differentiation time course
- Muscular differentiation time course
- Spermatogenesis cell types
- Reprogramming of fibroblasts to iPSCs
- Hematopoietic precursors and cell types