HsaEX0036420 @ hg38
Exon Skipping
Gene
ENSG00000168702 | LRP1B
Description
LDL receptor related protein 1B [Source:HGNC Symbol;Acc:HGNC:6693]
Coordinates
chr2:140839991-140850329:-
Coord C1 exon
chr2:140850102-140850329
Coord A exon
chr2:140840918-140841092
Coord C2 exon
chr2:140839991-140840085
Length
175 bp
Sequences
Splice sites
3' ss Seq
TTCTCTTTCCTGTTTTATAGATA
3' ss Score
10.89
5' ss Seq
GGGGTAAAG
5' ss Score
3.53
Exon sequences
Seq C1 exon
AAATGAAAAAATTTCTTCTTTATGCAAGACGTTCTGAAATCAGAGGAGTGGATATTGACAATCCATACTTTAACTTCATCACGGCATTTACAGTCCCTGATATTGATGACGTTACTGTGATAGACTTCGATGCATCTGAGGAACGTTTATACTGGACAGATATTAAAACACAAACCATTAAACGAGCTTTTATTAACGGAACTGGGTTAGAAACTGTTATTTCAAGAG
Seq A exon
ATATTCAGAGTATCAGAGGGCTAGCAGTGGATTGGGTGTCACGTAATTTATACTGGATTAGCTCAGAATTTGATGAAACGCAAATTAATGTGGCAAGGCTAGATGGCTCTTTGAAAACCTCAATTATCCATGGAATCGATAAGCCACAGTGTCTTGCAGCTCACCCAGTCAGGGG
Seq C2 exon
AAAACTCTACTGGACCGATGGAAACACAATTAACATGGCAAATATGGATGGCAGTAATAGCAAGATTCTGTTTCAGAATCAGAAGGAGCCAGTTG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000168702_MULTIEX3-8/13=7-9
Average complexity
S*
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence exclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=0.000 C2=0.000
Domain overlap (PFAM):
C1:
PF0005812=Ldl_recept_b=PU(70.7=37.7)
A:
PF0005812=Ldl_recept_b=PD(26.8=18.6),PF0005812=Ldl_recept_b=PU(0.1=0.0)
C2:
PF0005812=Ldl_recept_b=PU(86.5=97.0)
Main Skipping Isoform:
NA
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Cow
(bosTau6)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
CACGGCATTTACAGTCCCTGA
R:
ACTGGCTCCTTCTGATTCTGA
Band lengths:
242-417
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- The Cancer Genome Atlas (TCGA)
- Autistic and control brains
- Pre-implantation embryo development