Special

MmuEX6101255 @ mm9

Exon Skipping

Gene
ENSMUSG00000026950 | Neb
Description
nebulin [Source:MGI Symbol;Acc:MGI:97292]
Coordinates
chr2:52084268-52087798:-
Coord C1 exon
chr2:52087487-52087798
Coord A exon
chr2:52085476-52085679
Coord C2 exon
chr2:52084268-52084372
Length
204 bp
Sequences
Splice sites
3' ss Seq
GTTCACCACTACCTTTGCAGGCT
3' ss Score
6.85
5' ss Seq
AAGGTGAGT
5' ss Score
10.47
Exon sequences
Seq C1 exon
TACAAGTACAAGGAAGGCTACCGCAAACAGCTGGGCCACCACATTGGTGCTCGGAACATCAAGGATGACCCCAAGATGATGTGGTCCATGCACGTGGCCAAGATCCAGAGTGACAGGGAGTACAAGAAGGACTTTGAGAAGTGGAAGACCAAGTATAGCAGCCCAGTGGACATGCTGGGCGTGGTGCTGGCCAAGAAGTGCCAGATCCTTGTAAGCGACATAGACTACAAGCATCCTCTCCATGAGTGGACATGCCTGCCTGACCAGAATGATGTCATTCAGGCACGGAAGGCCTATGATCTTCAGAGCGAT
Seq A exon
GCTGTGTACAAGGCTGATCTTGAGTGGCTGAGAGGCATCGGATGGGTTCCCATTGGCTCTGTAGAGGTCGAGAAGGTGAAGAGAGCAGGTGAAATCCTGAGTGACAGGAAGTATCGCCAGCCTGCAGACCAGCTGAAGTTCACATGTATTACAGACACCCCAGAAATTGTCCTGGCAAAGAGTAATGCCATCACTATGAGCAAG
Seq C2 exon
CATTTGTATACAGAAGCTTGGGATGCTGACAAAGCCTCCATCCATGTCATGCCAGACACCCCTGAAATCCTGCTGGCCAAGAGCAATTCTGCCAATATCAGCCAT
VastDB Features
Vast-tools module Information
Secondary ID
ENSMUSG00000026950-'80-82,'80-81,81-82=AN
Average complexity
A_S
Mappability confidence:
100%=100=100%
Protein Impact





	

	
Alternative protein isoforms (Ref)





No structure available

		

			
Features


			

				
Disorder rate (Iupred):
  C1=0.000 A=0.000 C2=0.000
 
                        

				
Domain overlap (PFAM):

					





						

							
C1:
PF0088013=Nebulin=PD(37.9=10.6),PF0088013=Nebulin=WD(100=27.9),PF0088013=Nebulin=PU(55.2=15.4)

							
A:
PF0088013=Nebulin=PD(37.9=16.2),PF0088013=Nebulin=WD(100=41.2),PF0088013=Nebulin=PU(55.2=23.5)

							
C2:
PF0088013=Nebulin=PD(37.9=31.4),PF0088013=Nebulin=PU(55.2=45.7)

						

					

				








    
Main Inclusion Isoform:
ENSMUSP00000047763





     
                   









    
Main Skipping Isoform:
NA





     
      









    
Other Inclusion Isoforms:
ENSMUSP00000070747, ENSMUSP00000074773, ENSMUSP00000121411
          









    
Other Skipping Isoforms:
NA
  



Associated events






Other assemblies


mm10




Conservation


Human
(hg38)
chr2:151612186-151612389 
HIGH PSI
HsaEX6015957
(NEB)
Human
(hg19)
chr2:152468700-152468903 
HIGH PSI
HsaEX6015957
(NEB)
Rat
(rn6)
chr3:37743773-37743976 
HIGH PSI
RnoEX6016813
(Neb)
Cow
(bosTau6)
chr2:44655095-44655298 
Chicken
(galGal4)
chr7:34741714-34741917 
Chicken
(galGal3)
chr7:36868688-36868891 
Zebrafish
(danRer10)
No conservation detected
Fruitfly
(dm6)
No conservation detected




Primers PCR

	

		

			
Suggestions for RT-PCR validation

			

				
F: 
TGGCCAAGATCCAGAGTGACA

				
R: 
CAGCAGGATTTCAGGGGTGTC

				
Band lengths: 
293-497

			

		

	





	
Functional annotations
(Submit an annotation)

	


There are 0 annotated functions for this event 


		










GENOMIC CONTEXT[edit]












INCLUSION PATTERN[edit]










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