Special

MmuEX6107663 @ mm9

Exon Skipping

Gene
ENSMUSG00000027580 | BC006779
Description
cDNA sequence BC006779 [Source:MGI Symbol;Acc:MGI:2385169]
Coordinates
chr2:180963660-180964614:-
Coord C1 exon
chr2:180964261-180964614
Coord A exon
chr2:180963929-180964085
Coord C2 exon
chr2:180963660-180963827
Length
157 bp
Sequences
Splice sites
3' ss Seq
CTGCCCTCTTATCTACTTAGGTC
3' ss Score
10.4
5' ss Seq
AGGGTAAGG
5' ss Score
9.16
Exon sequences
Seq C1 exon
GTGGTTCTGCTTGGAGACCACAAGCAGCTTCGGCCTGTGGTCAAGAGTGAACAGCTGCAGAGTCTGGGGATGGATCGGTCTCTCTTTGAGAGGTACCACAGGGATGCCATCATGCTGGACACACAGTACCGTATGCATAAGGACATCTGTTCCTTCCCCTCCGTGGAGTTCTATGGGGGAAAGCTAAAGACCTGGTCTGACCTGAGGCGTCTGCCTAGTATCCTGGGTCACACTGGCAAGCCGAGCTGTTCCGTCATCTTCGGCTCTGTGCAGGGCCATGAGCAGAAGCTGCTGGTGTCCACCGAGGATGGCAATGAGAACTCTAGGGCCAACCCAGAGGAAGTCACACAGGTG
Seq A exon
GTCCGCATCATAAAGCAGTTGACCCTGGATCGGACGGTGGATCCCAAAGATATTGCTGTCCTTACACCCTACAATGCACAGGCTGCTGCAATCAGTAGGGGCCTCATGCAAAGAGGAGTCACCGGAGTGACTGTGACCTCTATTACCAAGAGCCAGG
Seq C2 exon
GGAGTGAGTGGCGCTATGTGATAGTGAGTACCGTCCGAACATGCCCCAGGAGTGATGTGGACCAGCGGCCAACAAAGAGCTGGCTCAAGAAGTTTCTGGGCTTTGTTGTGGACCCCCACCAAGTAAACGTGGCCATCACCCGGGCCCAGGAGGCGTTGTGCATCATTG
VastDB Features
Vast-tools module Information
Secondary ID
ENSMUSG00000027580-'18-21,'18-19,20-21=AN
Average complexity
A_S
Mappability confidence:
100%=100=100%
Protein Impact





	

	
ORF disruption upon sequence exclusion





No structure available

		

			
Features


			

				
Disorder rate (Iupred):
  C1=0.145 A=0.000 C2=0.000
 
                        

				
Domain overlap (PFAM):

					





						

							
C1:
PF130861=AAA_11=PD(6.4=13.6),PF130871=AAA_12=PU(45.4=79.7)

							
A:
PF130871=AAA_12=FE(25.1=100)

							
C2:
PF130871=AAA_12=FE(70.0=100)

						

					

				








    
Main Inclusion Isoform:
ENSMUSP00000091756





     
                   









    
Main Skipping Isoform:
NA





     
      









    
Other Inclusion Isoforms:
ENSMUSP00000029102, ENSMUSP00000084714, ENSMUSP00000104459, ENSMUSP00000112917
          









    
Other Skipping Isoforms:
NA
  



Associated events






Other assemblies


mm10




Conservation


Human
(hg38)
chr20:63560171-63560327 
HIGH PSI
HsaEX6079221
(HELZ2)
Human
(hg19)
chr20:62191524-62191680 
HIGH PSI
HsaEX6079221
(RP4-697K14.7)
Rat
(rn6)
chr3:176731598-176731754 
HIGH PSI
RnoEX0041518
(Helz2)
Cow
(bosTau6)
No conservation detected
Chicken
(galGal4)
chr20:14275986-14276142 
ALTERNATIVE
GgaEX0008715
(HELZ2)
Chicken
(galGal3)
chr20:9728028-9728184 
ALTERNATIVE
GgaEX0008715
([1])
Zebrafish
(danRer10)
chr2:42102331-42102487 
HIGH PSI
DreEX0005010
(HELZ2 (2 of 3))
Fruitfly
(dm6)
No conservation detected




Primers PCR

	

		

			
Suggestions for RT-PCR validation

			

				
F: 
TATCCTGGGTCACACTGGCAA

				
R: 
GGTCCACAACAAAGCCCAGAA

				
Band lengths: 
250-407

			

		

	





	
Functional annotations
(Submit an annotation)

	


There are 0 annotated functions for this event 


		










GENOMIC CONTEXT[edit]












INCLUSION PATTERN[edit]










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