MmuEX7000757 @ mm10
Exon Skipping
Gene
ENSMUSG00000057914 | Cacnb2
Description
calcium channel, voltage-dependent, beta 2 subunit [Source:MGI Symbol;Acc:MGI:894644]
Coordinates
chr2:14958766-14963982:+
Coord C1 exon
chr2:14958766-14958888
Coord A exon
chr2:14960655-14960791
Coord C2 exon
chr2:14963906-14963982
Length
137 bp
Sequences
Splice sites
3' ss Seq
ACTTTGGATTTTGTGTGTAGAAA
3' ss Score
5.36
5' ss Seq
CAGGTATGA
5' ss Score
9.46
Exon sequences
Seq C1 exon
ACAAAACCTGTTGCATTTGCAGTTCGGACCAATGTCAGATACAGCGCAGCCCAGGAGGATGACGTTCCGGTGCCTGGCATGGCCATCTCCTTCGAGGCCAAAGATTTTCTGCATGTTAAAGAA
Seq A exon
AAATTTAATAATGACTGGTGGATAGGACGGCTGGTTAAAGAAGGCTGTGAAATCGGATTTATTCCAAGCCCAGTCAAACTAGAGAACATGAGGCTACAGCACGAACAGAGAGCCAAGCAAGGGAAATTCTATTCCAG
Seq C2 exon
TAAATCAGGAGGGAATTCATCATCCAGTTTGGGTGACATAGTGCCCAGTTCCAGAAAATCGACACCGCCGTCATCTG
VastDB Features
Vast-tools module Information
Secondary ID
ENSMUSG00000057914-'14-28,'14-25,19-28=AN
Average complexity
A_S
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence exclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.138 A=0.436 C2=0.822
Domain overlap (PFAM):
C1:
PF120523=VGCC_beta4Aa_N=PD(2.4=2.4),PF0001823=SH3_1=PU(51.0=61.0)
A:
PF0001823=SH3_1=PD(44.9=47.8)
C2:
NO
Main Skipping Isoform:
NA
Other Skipping Isoforms:
NA
Associated events
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
GCATTTGCAGTTCGGACCAAT
R:
GATGACGGCGGTGTCGATTTT
Band lengths:
186-323
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Ribosome-engaged transcriptomes of neuronal types
- Neural differentiation time course
- Muscular differentiation time course
- Spermatogenesis cell types
- Reprogramming of fibroblasts to iPSCs
- Hematopoietic precursors and cell types