MmuINT0010416 @ mm9
Intron Retention
Gene
ENSMUSG00000015143 | Actn1
Description
actinin, alpha 1 [Source:MGI Symbol;Acc:MGI:2137706]
Coordinates
chr12:81269845-81271753:-
Coord C1 exon
chr12:81271673-81271753
Coord A exon
chr12:81270004-81271672
Coord C2 exon
chr12:81269845-81270003
Length
1669 bp
Sequences
Splice sites
5' ss Seq
CAGGTACTC
5' ss Score
7.04
3' ss Seq
GGGTTGGTTGTCTCCTCCAGGGA
3' ss Score
8.23
Exon sequences
Seq C1 exon
GATCACTCCGGCACGTTGGGTCCCGAAGAGTTCAAAGCCTGCCTCATCAGCTTGGGTTATGATATTGGCAACGACCCCCAG
Seq A exon
GTACTCGCCTCCTGCATGGAGCACGCTCAAGGGTGGCCTCCGGGGCGAGAAATAACGCATTTCTCCTTTTTTTCTTCTCTCTCTGTCTGACTCTCCCTGTCCCCCTTCCTGTGGGCCACGGGGCTCATCCTCTTCTGCTCTCCCTGCCTGCCCACTGTCCGGTTCCTCTGACTTCTGACCTCTGCCTTCGGCTATCTTTCCTGGGAACCTGCTTGGGTGTCCGCCTCCTCTCCCTCGCCACATCTCATCTGTGGACTGGACTTCTGCATTTCTTTGCTCTGACCTCCTTCAACATGTTCCTCCTACATTCTTCGGCTACTCCTATTCTTCGTACCATAAACTGGGTCATTCCTTTCCACTGTCTTCCTGGCCTCTGGCTGGCCCCTCCTCCTCCCACCTGTCTGTCCCTCCTGTGTCTTGGCGCCACTGCCCTACAGAAGAAGACGGGCATGATGGACACAGACGATTTCCGCGCCTGCCTTATCTCCATGGGTTACAACATGGTAACGTAAACCCCCTCCTCCGCCTGCCAGGCTTTCTAAAGTTGCCTTGGCCGGGAGGCAGCCACCTGACTGGAGAAGCTAAGTCTTAGTAATGGTGGACAAAGGCTCTTAGGTTAGAACTGCCCTCCTCGGGGGAGTCCCTTATGGCCATCCTTGGGGAAGATGGCACCTGAAAACCAGACCACCCATGGGGCCAGGGTGTGGCTGGGAGGCTTAGCCTCCTCATCATGGTCTCTGAACCAGTTTATCTTATGGTACTTTCTGTGGAGAAAGGGCTTTTTCACTCCCACAGTGAACACCAGCTGTGGACGGCCAACCCCAAGGTTTATAGAATGATAATTCTACTTTGTCTTACATGACAATGGTGGTTTATACTTCTGCCCTGGTAGTAGCTCCATCCAGACCTGCCACCACTCGGTCTTGACCCAGGCCTCTCGCTAACCTTGTTTTGTCCCCTCTGCATCCAGCTGAGCTGGATAGGACCTTAGCTGGATAGACAGGTGTCCACTGAACCAAGTACAGAGCCCATGGGATGCCCAGCAGGGTTAAAGGCTAGACTAGAAGTATACTCCGTAAATTCCACATTGCTATCAAAGCTTGTGGTCTCAGATGTAGTGAGGAAACCTCACAACGTGGTTGTAAGAGTTAAATAAAGTGATCACAAGGACTGCGTACTTGTCTGGCACACTTGTCATGTTAAGGAAACAGCATATGTTGGAGCTAGACTGCCTGCGTCCTAATCCTAGCTCCCTACCTCCTAGCCATGTGACCTTGGGTAAGTCACTTACCCTGTCTGGGCCTCAGATTTCCCATACAATGGGAATACTATGATTTTATTCAGTTGTGATGATAAGATGAATTTAGAATATTAGCTGGCCTATATAATACATGCTGTATGAGTGTTAGTTAGCCATTGTTGAAGTTATCGTCATTATAATTAATACTACCCATCATTTTCTGTAAGTGAAACCCAGAGCTCTGCAGGGGGTGGGAAGTCCTGAGACTCACAACGTTTGGGTCACTTTCTCACCCTGGGGCAACCCAAGCCAGATCAGATGTCTGTTGTGCCTCCTGTTCCAACCATAGGCAACTTGGAGCTGGAGGTACACTTGAGATGCCCCAGTAGGCCGTTAGGGTGACAGGTGTGGGTTGGTTGTCTCCTCCAG
Seq C2 exon
GGAGAGGCAGAGTTTGCCCGAATCATGAGCATTGTAGACCCCAACCGCTTGGGGGTAGTGACGTTCCAGGCCTTCATCGACTTTATGTCCCGAGAGACGGCAGATACTGATACTGCAGATCAGGTCATGGCTTCCTTCAAGATCCTGGCTGGAGATAAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSMUSG00000015143-Actn1:NM_134156:19
Average complexity
IR-S
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (disopred):
C1=0.000 A=NA C2=0.245
Domain overlap (PFAM):
C1:
PF134991=EF-hand_7=FE(31.3=100)
A:
NA
C2:
PF134991=EF-hand_7=PD(33.7=52.8),PF087265=EFhand_Ca_insen=PU(26.9=34.0)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
ACGTTGGGTCCCGAAGAGTTC
R:
TCCAGCCAGGATCTTGAAGGA
Band lengths:
222-1891
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Pre-implantation embryo development
- Muscular differentiation time course
- Spermatogenesis cell types
- Reprogramming of fibroblasts to iPSCs
- Hematopoietic precursors and cell types
Other AS DBs: