MmuINT0022846 @ mm10
Intron Retention
Gene
ENSMUSG00000027580 | Helz2
Description
helicase with zinc finger 2, transcriptional coactivator [Source:MGI Symbol;Acc:MGI:2385169]
Coordinates
chr2:181231687-181235591:-
Coord C1 exon
chr2:181235516-181235591
Coord A exon
chr2:181235372-181235515
Coord C2 exon
chr2:181231687-181235371
Length
144 bp
Sequences
Splice sites
5' ss Seq
CAGGTAGGT
5' ss Score
10.28
3' ss Seq
CTGACCCATCTCTCCTATAGGGC
3' ss Score
10.36
Exon sequences
Seq C1 exon
GTTAGTGCGCTGAGACAGGAGCTAAGAAGGAGGAACCTTGGTGAGGTGTCTGTGGGCAGCTTTGAGATCCTGCCAG
Seq A exon
GTAGGTGACAGAAATGTGGGCCAGAGGCTGGCCTAACAGGGAGGCAGCTTCCAGCCCATTTCTTTGATGTACATATATGTAGGGTGGGACTGAGGTGGCGGGGCTGCTGGTTCTACCTGGCCATCTGACCCATCTCTCCTATAG
Seq C2 exon
GGCGTGAGTTCCGGGTGGTGGTACTGAGCTCTGTCCACAACCGCAATAGTCTGCTTAGCCCAGGGGCACCAACCTCAGAGTTCTTCACTGAGCCTCGAGTACTGAACACGGTCATGACTCGTGCCCAGTCTCAGCTGGTGGCTGTGGGAGATGCTGTGGCCCTCTGCTCCTCTGGAGCCTGCAGAAATCTCTGGAGAAGCTTCATCCGCGAGTGCATAGAACACCACAGCGCCTTCCCTGAGGAGCTGTCACTGGAACAGATTGAGCAGGGTGTGGCCCAGAGACAGAACTGGGCCTCATTGACACTCAAAGCTAGGGGCCCAGAGACAGAGCAAAAATCTATGGCCCAGGGCCCACAAAGGCTCATAGCTGAAGGGACCATGGTCACGGTGAAGGCAGAGACCAGAGCCGAGGCAGCAGCCAAGGCACAGACTGCGGCAGTCGCAGCAGAAGACACAGCAAGCGGGAACTCAGCCTCTAGAGATGCAGCAGCAGAAGTGTCCACCCTGGAAGGGGGGATGTCTGAGGAAGATTCTGAGTCTGACTTCTGGCCCTCTGACTGGGAGCTCAATGCTGATGACGCCATCCTGAAGGAACTTCTCGACGAGAGCCAGCAAGTGACTGTGACTGTTAGGGAGGACGGACTTCTGGACACCGTGGTTTGCTCTGCACCACAGAAGGCCCGAGAGTACACAAACCTACCCTCATCTGTGCTGTGGAAGTTCCTGCGCTCAAACTCCAAGCAATTCCGCCGCTGCAGCTTCCTACAGGAGACCTTTGAGAGAGCATTGGCCACTCCGCTGGACGACATGGCCTCTAGCCCTATCCAGGTCAGGGGCCGTCTGAACTGTGGGATGGCATTCACGGGGGATGAGGTGCTAGTACAGATCCTGGGTCCGGCAGGAGATGACAGGTGCGTCCCTGGGAGCCTGCAGGGTCGTGTGATGGGTGTGTTGAAGAGGAGGAGGCACGAATTGGCCTTTGTGTGTCGGATGGATGAGTGGGACCCCCGCATCATGATCCCTATCAACGGTTCTGTGACTAAGATTTTTGTGGCAGAGATGAAGGACCCACAGCAAGTTCCCATCCACCGCCTCATTCAAGGCCAGGTGCAGCGTGTGAGGCATGAGACCCTCAAGCCTGAGGATCGGAGCACCCGGCTTTTCTGGGTCCGTATTGTCCTTTGGCGGGAACGTTTCTACTATCCACTAGGCATTGTCCTGGAGGTGCTGCCCAAGGCCATCACCTGGGAGCAGGGCCTTTATATCCTTGACCTAGAGCATGGCCTGAAGGCCCACACACCAGACCCAGCCTCAGTTTCCAAGGCTCTGCAGAGATACCGCTCAGAGCTAAACACGGCCGCTGGTCACCGAGAGGACTACCGCCACTTCCTGACCTTCACTGTGGACCCCCAGGGTGCCTGCAACCTTGACGACGCTCTTAGTGTCCGAGACCTAGGCCCAGTGTACGAGGTGGCAGTGCATATTGCTGATGTGGCCAGCTTGGTGCCCAAGGATGGGGCCCTGGACGTGGAAGCCCGCCAGCAGGGAACTGTGTTCTATGCCCCCAATAGGGAGCCAGTACTCATGCTGCCCGCCAGCTTGTGCCAGGATGCACTCAGCCTTCTCCCTGGTCAGGATCGCCTCGCCATCTCTCTCTTCCTCACCATGGAGAAAGGTGGTGGCCAGATCAAGAGCCTGCGATTTGCACCCTCCATAATCCGCTCTGACCGCCAGCTGTCGTATGAGGAAGCCGAAGAACTGATCAAGAGACACCCTGGGGCTGGCCTGGAGCTTCCAGCCCACCTGGACTCTGTGGAGGCCTGTGTTGTAGCTGCCTGCTACTTCTCTTGGATGTTACGTCGCCAGCGCCTCTCAGCTGCCTGTTACTATGAGCCGCCAGACGAGGACAGTGTGCTGGGCTTCCGCACAGCTCACATCATGGTCCAAGAGTACATGATCCAGTTTAACAGCCATGTGGCTGAATTCCTTGTGAGCAACAAGCACACACAGACACTCACACCACTCAGGTGGCAGCCCACACCCAGTAGGCAGCAGCTTGACAGTGTTTTCAAGAAGTACAGAGGCCTGGTGCCTCTGTCCCTGCACCTGTGCCACCACTCGAACACTGACTATACCCCCAACAAGCAGCTGCATCTCCTGACTTCCCTCTGGAAACAAGTGCAGCTTGCAGCTGGTACTCAGGATTACAGCCAGATGGTGGACCTTATTGCTGCAGATGACATGCACCCTTCACTGGCTCCTGCTTGCCTGGACTTGCGAAGGGCTCTAGGCCGCTCTGTTTTTGGTCGCTCCAGCCAGGGTAAGCAGCAACCTGCTGTTCACCACTCGCTACAGGTGGATTGGTACACATGGGCAACCTCACCCATCCGTAGGTATCTAGATGTGGTGCTGCAGCGGCTGATCCTGCTGGCATTGGGCCACAGGGGCTCTACATATTCTAACAGGGACATTGATGGGCTCTGCCTGGACTTCAGTCGCCAGTATGCAAGTGCCCAGAGCTACCAACGGAGGGCCTACAGCCTGCACCTGGCCATCCAGCTCAAGAGCCAGCCTCAAAACAAGCTGGGCTTCGTAGTGGATGTCGAGATGGGTGCCCGCTGCTTCAAAGTGCTTTTCCCTATAAACCGGGAAACGCTGCCCGATCCCTGCCCAATTCACTACCATTCCCTGCAGTTGGCTGAGCACCCCCAGGAGCTAGTGAGCCAGACAGGCGTGCGGCTTGTATGGCGGCGCCGCATGTACTCGGTGCAGGCGTCCAAGCTGCCTTTACCACTTCTGGGCACGAGTCTTGATCCACACACCCAGACTGTAGATGCAGCCCTGTGGATGAAGCTACTGATGCTGCTGAAGGAGCAGCGCTGGCCTGAGATAGCTGCCCTCATCCAGGAGCAAGATAAGCGTTTTCATCCAAGGGAGAAAGTAAAGATCCACCAGAGCCGCTGTGGACACTTTGTAGAGGTGGTCTACGAGCTGGGCAGTGGAGATACCCTGCAGGTTCAGCTTGGTTCCAGCCTGCAGCGGGGTTTCCTGGCACCAACCCTGAAGCTGTGGACTGTGGTCCCTGGCTTCAGCCTCTGTCTGGAGCACATGGAACGGCCAGGTGACTGCTTTTCAAGCCATGTGCACCAGGCTCTGCAAGACCAGTACCTTCAAGTCGGCGAGTACTCAGGTGCCTGGGGGCCACGCTGCGCCCTGGAGTCGCTCACCAATGCTGTTACAGAAAACGACTCCATTGTGCTGCACGATGTGCATATCTCTTGGGACACATCCCAGGGGCAGTTGCAGGGCACCTTCCAGCTGGAAGCTGCTTTTCTCCAGGAGAAATGCATCAACATCCACTTTGGCTGTTGCTACCTCTGCATTCGGCTGGAGGGGCTCCCTCTCCCCCTAGATAGCTCACTCCCTGGGCCTAGTGGCCTTGGCCCCTTCCTGAACATTGACCCCAATACATATACCTGGGTGGCCCATGGGCTGTCTGGTGACTGGGACCATGAACTGGCTGGTGGTGACTGGGACCAGGAGAATGTGGATGATCGGCAGGAGGCGCCCAAGCAGGTATATTTTCTCATCCATCACATGACCATGGAGAAGGTTCCAGAAGAGGTGCTGAGACCTAGCGCTCGGTTCACTGTGGAAGTGCTGTCTAAGCAGCTTCCTGACCT
VastDB Features
Vast-tools module Information
Secondary ID
ENSMUSG00000027580:ENSMUST00000121484:8
Average complexity
IR
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=NA C2=0.083
Domain overlap (PFAM):
C1:
PF130871=AAA_12=FE(12.2=100)
A:
NA
C2:
PF130871=AAA_12=PD(25.4=4.2),PF0077314=RNB=WD(100=29.1)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Associated events
Other assemblies
Conservation
Cow
(bosTau6)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
GTGGGCAGCTTTGAGATCCTG
R:
CGCTGTGGTGTTCTATGCACT
Band lengths:
256-400
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Pre-implantation embryo development
- Ribosome-engaged transcriptomes of neuronal types
- Neural differentiation time course
- Muscular differentiation time course
- Spermatogenesis cell types
- Reprogramming of fibroblasts to iPSCs
- Hematopoietic precursors and cell types