MmuINT0036263 @ mm10
Intron Retention
Gene
ENSMUSG00000041189 | Chrnb1
Description
cholinergic receptor, nicotinic, beta polypeptide 1 (muscle) [Source:MGI Symbol;Acc:MGI:87890]
Coordinates
chr11:69785050-69785879:-
Coord C1 exon
chr11:69785707-69785879
Coord A exon
chr11:69785198-69785706
Coord C2 exon
chr11:69785050-69785197
Length
509 bp
Sequences
Splice sites
5' ss Seq
CAGGTAAGA
5' ss Score
10.77
3' ss Seq
TCCCCACCCTACACACACAGGTT
3' ss Score
6.12
Exon sequences
Seq C1 exon
ATCTTCATTCACAAGCTCCCTCCATACCTGGGTCTGAAGAGGCCCAAACCCGAGAGAGACCAACTCCCTGAACCACATCACTCTCTTTCTCCAAGAAGTGGCTGGGGCAGAGGAACTGATGAATATTTCATCCGGAAGCCTCCAAGTGATTTTCTTTTCCCTAAACTTAACAG
Seq A exon
GTAAGACCTACACTAGTCGCTGGGTGTGGTGGTGCACGCCTTTAATCCCAGCACTCGGGAGGCAGAGGCAGGCAGATTTCTGAGTTCGAGGCCAGCCTGGTCTACAAAGTGAGTTCCAGGACAGCCAGGGCTATACAGAGAAACTCTGTCTCGAAAAACAAAACAAACAAAAAAACAAAACAAAACAAAAAACAACAACAAAAAAAGACCTACACTAATCAATCACTTGGGCAAGGGAGAGCTACAGCTCCCAGAAGACAGTGGAAGGTAATGTGGCCTAGCATCATGGGAGTTGTAGGAACCTTGTCTGTGCTTGCATTGTAAAAAGGTGGCATTTAAAAGTTTAAAGAGCCAGAAACTTGCAAAAGTCTGGAGAGGTCGGAAGGTCTCTCCCAGGTACGGAAGGTTGTTGGAGGAGGCAGCTGGAGCAGGGTTGACAGGTCAACGGGAACTTCACATTCTCTTTGAACCCAGGGTGTGGTCAAACAGTCCCCACCCTACACACACAG
Seq C2 exon
GTTTCAGCCTGAATCATCTGCCCCGGACCTGCGACGATTTATCGATGGTCCAACCCGGGCTGTAGGTCTGCCTCAGGAGCTACGAGAGGTCATTTCCTCAATCAGCTACATGGCCCGACAGCTTCAGGAACAGGAGGACCACGACGCA
VastDB Features
Vast-tools module Information
Secondary ID
ENSMUSG00000041189:ENSMUST00000045971:9
Average complexity
IR
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.276 A=NA C2=0.000
Domain overlap (PFAM):
C1:
PF0293211=Neur_chan_memb=FE(24.2=100)
A:
NA
C2:
PF0293211=Neur_chan_memb=FE(20.8=100)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Chicken
(galGal4)
No conservation detected
Chicken
(galGal3)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
ATCTTCATTCACAAGCTCCCTCC
R:
GTCGTGGTCCTCCTGTTCCT
Band lengths:
318-827
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Pre-implantation embryo development
- Ribosome-engaged transcriptomes of neuronal types
- Neural differentiation time course
- Muscular differentiation time course
- Spermatogenesis cell types
- Reprogramming of fibroblasts to iPSCs
- Hematopoietic precursors and cell types