MmuINT0050325 @ mm9
Intron Retention
Gene
ENSMUSG00000030409 | Dmpk
Description
dystrophia myotonica-protein kinase [Source:MGI Symbol;Acc:MGI:94906]
Coordinates
chr7:19674260-19676389:+
Coord C1 exon
chr7:19674260-19674345
Coord A exon
chr7:19674346-19676277
Coord C2 exon
chr7:19676278-19676389
Length
1932 bp
Sequences
Splice sites
5' ss Seq
CAGGTGAGC
5' ss Score
9.6
3' ss Seq
TAGCCTCTTCCTCTTCTCAGAGA
3' ss Score
7.94
Exon sequences
Seq C1 exon
GAGACGCTGTCAGACATGCAGGAAGACATGCCCCTTGGGGTGCGCCTGCCCTTCGTGGGCTACTCCTACTGCTGCATGGCCTTCAG
Seq A exon
GTGAGCACGACTGCCCCCTGCTGGGGCCTGTGTGCAGGCCCACCACAGCCACTCAATTGAAGGCTCAGTCTTCAAACCAAGTATTCCTAGGAGCTGTCTAAGTTAGGCTTTCTGCTGCTGCGATGAACCCTGACTAAAAGCAAGCTGGGGAGGAAAAGGCTTATCGGGCTTACGTTTCCACATGGGAGCCCATCACTGAAGGAAGCCAGGACAGGAACTCACAGCGGGGCAGGAACGTGGAGCTGATGCAGAGGCAATGGAGGGGAGCTGCTTACTGACTTGATCCTTATGTCTTCCTCAGCCTGTTTCCTTGTAGAGCCCAGGACCACCAGGCCAGTGAGGGCTCCACTCACAATGGGCTGAGCTCTCATCTATGATCACTAGTTATGAAAATGCCCGATAGGCTTGCCTGCAGCTTCAGTTTTTGAGGCACTTTCCTTCCTTCCTTCCTTCCTTCCTTCCTTCCTTCCTTCCTTTCTTTCTTTCTTTCTTTCTTTCTTTCTTTCTTTCTTTCTTTCTTTCTTTCTTTCTTTCTTAGTCTTTTAGAGACAGGGTCTTTCTATGTAGCTCTGGCTGTCTTGGAATTCATTCTGTAGACCAGGCTGGTCTTATTTATTTATTTTATGTATGTGAGTCCACTATCACTGTCCTCAGACACACCAGAAGAGGGCATCAGATCCCATTACAGATGGCTGTGAGCCACCATGTGGTTGCTGGGAATTGAACTCAGGACCTCTGGAAGAGCAGCCAGTGCTCCTGCCCTGTAGAGGCATTTTCTTCATGAAGGCTGTCTCCTCTCTGATGACTTGATGACTCTAGCTTGTTGTGTCAAGTGGACATAAGACTAGGAAAGCAGCTACACATGCACTTTGTTTATTTTTGTTTTGCTTTTTGAGACTGGGTCTCTCCATCTCATAGCTCTGGCCATCCTGCCTGGTGACATTCCAGTCCAGTTGTATAACCTAAGAATCTGAGACTCAGCCTTGCAGAATCCTGCTATTAACGGGTCTAGGACACTCCATAGAATCCAGGATCTTAGAAAAACAAACCTGAAGTGTGACAGTTTATTTTAAGAACACAATTGGAGCACATAACAATAATACAACTTTTCAGTTTTAAAAAGTTTTCTGTCTTGTTTTTTGAGGCAGGAGCTCCTTAATATAGTCTAAGCCGCCCTGCGAGTGCTGTGATTGATGGGCATGTACCACCATGCCTAGTCAATAAAGCCTTTAAAAAGCATCCGTTATGCTGGCTGTGGTGCCACAAACCTGTAATCCCAGCACTTAGAAGGTAGAGGCAAGATTATCAGAAATTCAAGGCCATCCTGGGCTATACAGTAATCTAAGGCTAGCCTGGTCTACAAGAGACTCTGTCTAAAGAAACAAAAGATAAATAGCACCCACTATTGCTAGGCAATATAACCCTATAACCCCACCATTGAGGAGGCTGAGGCTGGAGCATCACTGCAAATTTGAGGCCAGGATGGTCAACAAATAAGTCCCAGAGCTGGCATAGAGGAACTCTGTCTCAACAATAAAGAGAACTTATCTAGCATTTATGAGGGTAAATAAAAATTTACCATTGCCACAAAAAATGTAAATGAAGAGACTGCTTTTAGGAGTGAACTGGGAAGCAGGGAACACTTAGAGGATGCTCACTCACACAGGTATCCACCATCAGGCATGCCTCAGGCCTGCACAGGGAAGGACAACTTGTTTCATGATTTGCAAGCAGCATCCCATGCTCCTTAGAGCGGGTTGGGCCCAGCCCACCCTCTGTGGAGTTATCGCTCAGCCAGGCAGCAAGGCAGCCAAGGTGCTGAGGCCCTGGCAGTCTGCTCTCTTCTCTGCTCTGAACCTCCTTTAGCTTTAGCCTAGGAGCCTGGCCTGGTGCCCACAGGCTAGGGAGTCCCTAGCCTCTTCCTCTTCTCAG
Seq C2 exon
AGACAATCAGGTCCCGGACCCCACCCCTATGGAACTAGAGGCCCTGCAGTTGCCTGTGTCAGACTTGCAAGGGCTTGACTTGCAGCCCCCAGTGTCCCCACCGGATCAAGTG
VastDB Features
Vast-tools module Information
Secondary ID
ENSMUSG00000030409-Dmpk:NM_001190491:9
Average complexity
IR-S
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.202 A=NA C2=0.684
Domain overlap (PFAM):
C1:
NO
A:
NA
C2:
PF104814=CENP-F_N=PU(21.9=55.3),PF041569=IncA=PU(26.2=84.2)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
Associated events
Other assemblies
Conservation
Chicken
(galGal4)
No conservation detected
Chicken
(galGal3)
No conservation detected
Zebrafish
(danRer10)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
GAGACGCTGTCAGACATGCAG
R:
GACACTGGGGGCTGCAAG
Band lengths:
182-2114
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Pre-implantation embryo development
- Muscular differentiation time course
- Spermatogenesis cell types
- Reprogramming of fibroblasts to iPSCs
- Hematopoietic precursors and cell types
Other AS DBs: