MmuINT0050876 @ mm9
Intron Retention
Gene
ENSMUSG00000005237 | Dnahc2
Description
dynein, axonemal, heavy chain 2 [Source:MGI Symbol;Acc:MGI:107731]
Coordinates
chr11:69244561-69246482:-
Coord C1 exon
chr11:69246356-69246482
Coord A exon
chr11:69244748-69246355
Coord C2 exon
chr11:69244561-69244747
Length
1608 bp
Sequences
Splice sites
5' ss Seq
GTGGTGAGT
5' ss Score
8.95
3' ss Seq
TCTTCTCTCTCTTCCCCAAGGTC
3' ss Score
10.95
Exon sequences
Seq C1 exon
GTACACCTGCCGAACCCTTTTTGAGCGCCACAAGCTTCTGTTCAGTTTTCACATGTGCGCCAAAATCCTGGAGACGTCCGGCAAGCTCAACATGGATGAGTACAACTTCTTCCTGCGTGGGGGTGTG
Seq A exon
GTGAGTTGGTGGGAGGGCACCTCCCTGCACGGGGGTCACATGGGGATGGCAGCAGGTGTGTGGAGGAGGCCAAGTCAGAGGGAGGGCAGAATCGAAGGCTCCCCAGAAACGTGAGTACTCGGAGCACCTGGGGCTGAGGGGCTGACTTGTTACGTGACTCTGGAGACCCACTTCAAGCTGGTCATCTGATCACCTCTTACATGAAACCCAGGTATACTTGACTCTCTTCCTTAAAAAAAAAAAAAAAGTCAGCTGAGTTTCATGTACTTATAACCTCAGCAGGACAGTGAAAGATGGAGACAGATGCTTACCACCCACCTAGCCTGACCTAGCCTAATTGGCTAGCTTCCAGTTCAGGGAGAGATCTGATCTCTAGGGAATAAGTGAAGAGCAATGGAGGCACCCACCATCATTCTCTGCCTTTCACACACTTGCACACCTGCACGTACACCACACGCACACGCGGCGTGTGCACACACACCAAAGTGGAGGGAAAAACACAGATTTTCGTTTAAAAGCATGAGTATAAGAACAGATGGGAGGAGTATGCCAACAGTGGGTGGGTTTGGAGCTATTTCTGCCACTAAGCCACCAGAGGGCATCAGCTTCCTAAACTTTAACTGTTGTGGGTATGCAGTGCCCCCCCACCATGCATCCCTCAGTAAAGGTGGCTTTGCGTCCATCTTAGATTCCTGTCTCCTCATTAGGCATTCACTCTGCTTCACAGAAAACCAACACCAAACACACACACACACACACACACACACACACACACACACACACACACACACACGACGGGAGGAGATAACTTAAAATATCATGTTTTATTTTTAATTAAAACATAGCAATTGGGCTGGTGAGATGGCTCAGCGGGTAAGAGCACTGACTGCTCTTCCAAAGGTCCCGAGTTCAAGTCCCAGCAACCACATGGTGGCTCACAACCACCCATAATGAGATCTGATGCCATCTTCTGGTGTGTCTGAAGTCAACTACAATATAATAACATTATACATTATATTAATAATATACAACAATAAAAATAAATCTTAAAAAAACATAGCAATTGCACAGTCTTACTGGGTATAGCGTGGCTTAATTTTTTTTTTAAGATAAGGTTCTTTATAGCTTATGCTAGCCTAGAATGCACTGTATAGCCCAGGCTGACCTTGAATTCCTGGTCATTTTCTTGTCTAGCCTGGCACCTGGGTGTTTTGGTGACAGGCACCATGCCTGGCTTGCAATGAGGTGTTTCAGTATCAGTACATACATGTGTGTGTGTGTGTGTGTGTGTGTGATGACCAGATCAGGGTAGTTGGAATATTCATTAAAACAAACATTTAGAGCCGGGCATGGTGGCGTACCCCTTTAATCCCAGCACTTGGGAGGCAGAGGCAGGCGGATTTCTGAGTTTGAGGCCAGCCCCAGGACAGCCAGGGCTACACAGAGAAACCCTGTCTCAAAAAAACAAAACAAACAAACAAACAAAAAACCAAAAAAAAAAAACCAAAAACCCCAAAACTAATACAAACATTTGTCTTTTGTTGTTGTTGTTTTATTTTAGGAACTTTCCTTTTGAGGGTTCTAGGCATCTTCTCTCTCTTCCCCAAG
Seq C2 exon
GTCCTGGATCGTGAAGGCCAAATGGACAATCCATGTACCAGTTGGCTGGCAGATGCCTACTGGGATAATATCACAGAACTGGACAAACTGACCAACTTCCATGGGCTCATGAACTCCTTTGAGCAGTACCCTCGGGACTGGCACCTGTGGTACACCAACTCTTCCCCGGAGAAGGCCATGCTGCCAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSMUSG00000005237-Dnahc2:NM_001081330:73
Average complexity
IR-S
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=NA C2=0.016
Domain overlap (PFAM):
C1:
PF0302810=Dynein_heavy=FE(5.9=100)
A:
NA
C2:
PF0302810=Dynein_heavy=PU(8.2=92.1)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Associated events
Other assemblies
Conservation
Chicken
(galGal4)
No conservation detected
Chicken
(galGal3)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
GTACACCTGCCGAACCCTTTT
R:
GCAGCATGGCCTTCTCCG
Band lengths:
311-1919
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Pre-implantation embryo development
- Muscular differentiation time course
- Spermatogenesis cell types
- Reprogramming of fibroblasts to iPSCs
- Hematopoietic precursors and cell types
Other AS DBs: