MmuINT0068138 @ mm10
Intron Retention
Gene
ENSMUSG00000041798 | Gck
Description
glucokinase [Source:MGI Symbol;Acc:MGI:1270854]
Coordinates
chr11:5904361-5906576:-
Coord C1 exon
chr11:5906477-5906576
Coord A exon
chr11:5904545-5906476
Coord C2 exon
chr11:5904361-5904544
Length
1932 bp
Sequences
Splice sites
5' ss Seq
TGGGTAAGG
5' ss Score
9.08
3' ss Seq
TAAATGTGTCCATCCCGTAGGCA
3' ss Score
8.14
Exon sequences
Seq C1 exon
GACTTTGAGATGGATGTGGTGGCAATGGTGAATGACACGGTGGCCACAATGATCTCCTGCTACTATGAAGACCGCCAATGTGAGGTCGGCATGATTGTGG
Seq A exon
GTAAGGGCTTCTCCCCCTTGCAACCTTTGCAGGCTGCACAGGCTCATAGCACTCAGTGCCAAAGCATTAACAACAAGAGCCAGTCAGAACAGGCCTGGTGCCTGAGCCAGGCAGCCGTGGGGTTCGGAGTGGGAGAGAATCGGCAAAATGGCACCATTCATGTGGCTTGTCACCCCTGCCCCAGTCTGGCTCTGCTGCCAACAGCGGACCCAGCTCTGAATCTATGAACTGCCAGATCCTAAACCTACTCTGGAGGGAAGGAGATTCCAGAAAAAGAAGCCAAAGCTAGCTCAAGCTTGTCCCGCCCACCTCAATCAGGGTGGGAGCTCCACACCAATGCCCTCCTCCCGCCCTGCCCCCACTGTCTCAGAGGTTCCTGAGTTCTTCCGAAGCAGTATTTCAACCAAATCAGTTCCCTGCTCTGCACACTGGTGTAGGGATGTATGTTTGCACACTCTGCACACTGGTGTAGGGATGTATGTTTGCACTCTCTGCACACTGGTGTAGGGATGTATGTTTGCACTCTCTGCACACTGGTGTAGGGATGTATGTTTGCACTCTCTGGGCACTGATTACCCAGAAAACCCGTGTTTTAGGTGCTTCAGAGACAGATCTCCAATAATGTGTTTATATTCATAGGCTCTCATCTGTACTTAAACTTGTGCAATAAATCCTGGAACTCATTTTGTAGACCAGGCTGTCCTCGAACTCAGAAATCTGCCTGCCTCTGCCTCCCAAGTGCTGGGATTAAAGGCGTGTGCCACCACGCCCAGCTTTATAAACATCATTCATCTTATATTATCTTATATATATATAAAACATTATAGGTGTACATATACACATACACACACATACACATACATATACATATATTTGTTGCTGTTGTTGTTCTGAGACAGGGTCTCATTATATAACTCTAGCTGTCCTAGAACTCACTCTGTAGACCAGGCCTCGAACTCACTCTGTAGACCAGGCCTCGAACTCACAGAGATCGTTCTGTCTCAGCCTCCAGACTGTTGAGACTAAAGGTACATGCCACCACACCCGGCTACGTGCATATATTTTATGCTCTAGCCTGACCCCTCTGCATCTCTTCTTATTTCCTACTTTTACTTTCAATCTTGCCTTGGTAGTGAAAATTTCTCTCTCCAGATGTCCTTGGCTATCCCTGCCTCTACGTTTCCTCTTTAACTCCTCCTGGAGCTCCCAAGACACTTCGATCTGAACTTAGCCTAGCCACCCGCAGCTACTCTGCCCAGGCACAGCTCCTCTGTGGCATGATCCGAAAGTGATGGGTATCTTTTGTTGGCACATGACAAACTGCAGCAGGCCCTGCCTACGGTGGCTTCTGAGTGGCTCTGAGGTACCTACCTACATGGTGCCTCACTCACTTTGAGAGTCCTCTAAAAGGGTTCAGGAGAGAGACTTCAAGATGTGCCTGCAGCGTGCTAGAGAGCAAGGGGCTGGAGAGATGGCCGAGCTGTTAAGAGCACTCAGTGTTCTTCCAGAGGACCTGGGTTCAATTCCCAGCACCCACATGGTGACCCACAACTGTCTGTAACTCTAGTTCCAGGGATCTATAACTTCCACTGGCTTCTCTAGGAGTCAGACAGACACATATGTAGTGTGCAGACAAAATACTTATATACAGAACATTTTTAAAAATTTAAAACCATGACACCTCACATTCATTTCCGGTGTCAAACCCACATTGGCACGCCTGGTTTTTCCTCCATCCCCCTGACTTCCCAGGTAAGGAGCTCTCGTTGGAGGGCCATCTGCAGACTGACCCAACTACTCTTCACTGCACAGCTGCTCCAGCCGTCCAGCATTCACCCCCCGGGTCTTATAGCGTAAATGTGCCTCATCCCGTAGGCACTGGCTGCAACGCCTGCTACGTGGTCTTATAGCATAAATGTGTCCATCCCGTAG
Seq C2 exon
GCACCGGCTGCAACGCCTGCTACATGGAGGAGATGCAGAATGTGGAGCTGGTGGAAGGCGATGAGGGGCGCATGTGTGTCAACACAGAGTGGGGCGCCTTCGGGAACTCCGGTGAGCTGGACGAGTTCCTCCTGGAGTACGACCGGATGGTGGATGAGAGCTCAGTGAACCCCGGTCAGCAGCT
VastDB Features
Vast-tools module Information
Secondary ID
ENSMUSG00000041798:ENSMUST00000109823:6
Average complexity
IR
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=NA C2=0.020
Domain overlap (PFAM):
C1:
PF0034916=Hexokinase_1=PD(11.1=67.6),PF0372711=Hexokinase_2=PU(10.8=23.5)
A:
NA
C2:
PF0372711=Hexokinase_2=FE(25.4=100)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Associated events
Other assemblies
Conservation
Chicken
(galGal4)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
ACTTTGAGATGGATGTGGTGGC
R:
CTGACCGGGGTTCACTGAGC
Band lengths:
278-2210
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Pre-implantation embryo development
- Ribosome-engaged transcriptomes of neuronal types
- Neural differentiation time course
- Muscular differentiation time course
- Spermatogenesis cell types
- Reprogramming of fibroblasts to iPSCs
- Hematopoietic precursors and cell types