MmuINT0074509 @ mm10
Intron Retention
Gene
ENSMUSG00000026879 | Gsn
Description
gelsolin [Source:MGI Symbol;Acc:MGI:95851]
Coordinates
chr2:35282380-35284109:+
Coord C1 exon
chr2:35282380-35282601
Coord A exon
chr2:35282602-35283904
Coord C2 exon
chr2:35283905-35284109
Length
1303 bp
Sequences
Splice sites
5' ss Seq
CGGGTGAGT
5' ss Score
9.89
3' ss Seq
TCTGTCCTGTCTCTCTGCAGCCC
3' ss Score
13.42
Exon sequences
Seq C1 exon
GCTAGGGCGGGATGGGACGGCCGGTTACTTAAAGGTTGGGGCGACCAAGGGTCCGCGGCCGCAGCCTGGGTCCTCACCGTCGCCATGGCTCCGTACCGCTCTTCACTGCTCTGCGCGCTGCTCCTCCTGGCGCTGTGCGCACTGTCGCCTTCCCATGCAGCCACCACATCACGGGGCAGGGCCCAAGAGAGGGCGCCCCAAAGTCGGGTGTCTGAGGCGCGG
Seq A exon
GTGAGTGCCCGGGGTCCCCGGGGCTCCCCGAGTAATTGTCTATTGTAAGTTCTTGCAGATACAGCGCTAGGAAAAGGGGAGTAATTCAGGTGTAGAATGGAAAAACTGTTTTGTTGCTTTGTAAGTATGTCTTGCTGCTTCGGGGCTCCTGGGGGCGGGGTTCGGGGGCCGGGGCCAAAGCTCTTTCCTTCCTGCAGGCTAACCTCACCTTGGCCGGATCTTTCCCCACTACTGATTTGGATCCCATCTCCTTTATCATGTCTAACTACTGCCCTTCTTGCTGGTCTTTCTCAGAGTCCTCTGCGTTTGCTGTTTGCTGTTTGTCTGTCCCCTCCCGTTCGGTTTCCCCTTTGAAAGCCTCTGGACAGGACTGTTATTTTATTCTCTTCTCTCTACCCTGATTGTGGTCTCCTCCCCTGCCCGACCCCTCCCACTTGTCTGCCCTTTCTGTTCTCTACTCTCCACTACCTGAGTTTTTCTCCCCAATCGCTTCTGACTTCTGCCTGCTTTTTGTTCCAACCAGACCTTCCTCTGTCTGAGGTGACCTGCTGACATCCCTCCTTGGGCGCAAACCTAACCGTCTGTCCCATTGGCACCTACAGAGCATGTCTGGCAGCCTTTCCCACCCTCAAACCTTCTCCTAACAGGTTCCCCCTGCAGACTTCAGGCTCCATTCCTTCCCCCTTTCCCAAGATGTGGAAATTTGGTGGGTGGGATGCTGGGGGCGGGGCAGGAGGGAGGAGGCAGACAGCTCAGGAGGCCACTTGGGCCCACTAAGCCAGTCCTTAGTGGGCTGTGATGATCCTTCCCCTTCCAAGGAGCAAAACCAACCACGGGACCTAGGATCGGGCCCCTTGCCCTTTGGTCCTGTTTCCCCATTTGCAGAGTAGGGGTGGATAATGCGTCCTAAGCCACAAAGGTTCTGGAAGAGAGCATGCAGAGTCACTGGGGACTGAGAGATTTGCCACTGCTATCTGGGAGTGTCTATCCATAGGGGCAGAGAGTGCCTTTGGAGTCCAGGGCTATCCCTCTATGTTGTCTCCCAAATGGGGGCCCCTGAAAGACAGCCTGCCTCTTTGTGCCTTAGCTATCTCCCCAAAAGGGAGGGAGCTCTCTGCCTCCTCTGTCATATCACCAACTAGGAGAGCAGAAAGGAAGACAGCCTGGCCTGGCCAGAAACTCCCAGAAAGGGGTTGATTCTCCTCTAGCACAGGGAGAGCTCGAAGCTGCCCTCCCTCATGCCTGGGGTCTCTCCTTGCTGAGACCCACACTTCTGCTCAGGTTCTGTCCTGTCTCTCTGCAG
Seq C2 exon
CCCAGCACTATGGTGGTGGAGCACCCCGAATTCCTGAAGGCAGGGAAGGAGCCTGGCCTGCAGATCTGGCGTGTGGAGAAGTTTGACCTGGTGCCTGTGCCCCCCAACCTCTATGGAGACTTCTTCACGGGTGATGCCTATGTCATCCTAAAGACTGTGCAGCTGAGGAATGGGAATCTGCAGTATGACCTCCACTATTGGCTGG
VastDB Features
Vast-tools module Information
Secondary ID
ENSMUSG00000026879:ENSMUST00000028239:1
Average complexity
IR
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion (1st CDS intron)
No structure available
Features
Disorder rate (Iupred):
C1=0.413 A=NA C2=0.000
Domain overlap (PFAM):
C1:
NO
A:
NA
C2:
PF0062617=Gelsolin=PU(50.0=60.9)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
GGACGGCCGGTTACTTAAAGG
R:
TGACATAGGCATCACCCGTGA
Band lengths:
353-1656
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Pre-implantation embryo development
- Ribosome-engaged transcriptomes of neuronal types
- Neural differentiation time course
- Muscular differentiation time course
- Spermatogenesis cell types
- Reprogramming of fibroblasts to iPSCs
- Hematopoietic precursors and cell types