MmuINT0084216 @ mm10
Intron Retention
Gene
ENSMUSG00000001281 | Itgb7
Description
integrin beta 7 [Source:MGI Symbol;Acc:MGI:96616]
Coordinates
chr15:102224558-102227601:-
Coord C1 exon
chr15:102227398-102227601
Coord A exon
chr15:102224760-102227397
Coord C2 exon
chr15:102224558-102224759
Length
2638 bp
Sequences
Splice sites
5' ss Seq
CTGGTAAAC
5' ss Score
4.14
3' ss Seq
AGCCTCCTCTTGGGGTACAGAAC
3' ss Score
3.41
Exon sequences
Seq C1 exon
GCCATGGTGGATTCATCAACTGTTCTCATTTTTCTGCTGGTTCTGGGCGGAGGTCAGAGTGAGTTAGATACCAAGATTACATCCTCTGGGGAGGCCGCAGAATGGGAGGATCCTGACCTGTCTCTGCAGGGATCCTGCCAGCCAGTTCCTTCCTGCCAGAAGTGTATTCTCTCACATCCCAGCTGTGCATGGTGCAAACAACTG
Seq A exon
GTAAACATGGGTGTGTGTGGTCCTGAACATGTGTGATGTGCGTTGTGTAGGTAGATTTGTGATTTTTTTTTGGGGGGGGGGGAATACTGTCCCTTCTCATGTGTGACTGAATTTGGACAGACAGGATTCCAATGTGTGACTCATATGCGTGTAAGTTTCTGAGCATACGTGAACAGAACCCGTGACCCATGAGCTCAGAGGAAGATGTCCTTGTGGGAGTTCGTGCTTCTGCATGTGAGAAAGTAGACTGGCCAGTTACGTATTCTGTGACAACATGCAACAGAAACATACTTCTTATGAATTGAAAGGCTTGGAATTCAAGAGCAAAGTGCTGGTTCATTTGGTTCTCTCTGGAGCATTTTTTCCTGGCTTAGAGATGGGCTACCTTCCTGCTGTATTACGACATGGGGTTAGGGTGTGGGGAGGAGACCCCTCTGCTGTTGACTCTCTCTCTCTCTCTTTAAAAGATTTATTGATTTTATTTATATGAGTACACTGTAGCTGTCCTCAGACACACCAGAAGAGGGCATCGGATCCCATTACAGATAGTTGAGAGCCACCATGTGGTTGCTGGGAATTGAAAGCAGGTCCTCTGGAAGAGCAGTCAGTGCTCTTAACCTCTGAGTCATCTCTCCAACCCTATTGATTCTTTATAAAAGATATTTATTTTATGTGCATGTGTGTTAGTGTGTGGATGTGCACCCCATGTCTGCAGGTACCTGTGGAGGTCAGAAGAGGGTGTTGGATCCCTAAGAACTGGAGTTACTGGTTGTAAACCATCACATGGGTGCTGGGAACTGAACTTGGGTCCTCTTAAAGCGCAGTAGGTGCTGTTAACTACTGAGCCACCTCTCCAGCCCCAGCTGTCACATCTTAAGGGGCACATCTCATCTCAAGGGTCTCACTCTCAGGACTTCACCTAAGCCTAACCTCCACCCAAAGGCCTCACCTCACATACCATCAAAGTGAGAGTTAAAAATTAAGCACAAGTCAGGAAATTATGGCATGTGCCTTTAATCCAAGCACTTGGGTGGCAGAGGCAGGCAGGTCTCTGTGAGTTCGAAACCGGCCTGTTCTATAATGTGAGTTCTAGGACAGACAGAGCTACATATTGAGGCTCTGTCTCAGACAGTAGATGGATAGACACATTGATAACAATAGATAATTTGGAGGGAGAATCCAGTCCATAACAGAACATGCATGATGAGGCTTCTGAGTCAGGCATGTATGTGCAGATTATGATTTCCCGGCATGCATTCTGGAGAGGGAAATATATGAAGGCTTCCAAAAACCTGTGGATTTATGTGAGTGTATGGGAGGAGGCCACTGGGAAGGTCTGGGGTACCTGAGGGGTAAGGATGCTGGGGAGTGTGTATTCCTTGCTGGTCAAAAGAGCTGTTCTTGGGCTGGAGAGATGGCTCAGGGGTTAAGAACACCGACTGTTCTTCCAGAGGTTCTGAGCTCAATTCTCAGCAACCACATGGTGGCTCACAACCCTCTGTAATGGGATTTGATGCACTCTTCTGGTGTGTGTCTGAAGACAGCTACAGTGTACTTATATACATAAAAATAAATAAAAAATTAGTTTTTTAAAAAAGCTGCTCTTTATGGATGCCTTAAAGAGGAAGTGCTCAGCCAGGCGTGGTAGCACACGCCTTTAATCCCAGCACTCGAGAGGCAGAGGCAGGTGGATTTCTGAGTTCGAGGCCAGCCTGGTCTATAAAGTGAGTTCCAGGACAGCCAGGGCTATAGAGAAACCCTGTCTCGAAAAACAAAAAAAAAAAAAAAAACAAAAATAAAAAAAAAAGAGGAAGTGCTCGTGGAAGGGCCTCTGAGGCAGTCTCTCACAGAAAGATGGAGATTTAGATAAGTGCAGGCTTGGTAAGATAGACACACTGACAGGCAGCCATGTTTACAGCTGCCTAGGGGGCCCAAGAAACTACTGATCATGAAACTCCGTAGTCAGGGAGGCAGAGGACCTAGACAGTGGCTAGAGAGATAAGCCCCTGGGAACAGCTGCTGGTCTGTATCTACCTCTTCCGTTCCCTAGGGGCTGGCACCATTGCCCACGGAGAAGCCACCTAGCCATTTCCTTCCCCTGCGGCTTGTCAGTCAGTGCAGGGTACCAGACGTCGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTACGCGCGCGTGCGTGCACGTGTGTCTTTCTGTCGTCTTTATCGTCCTCCTTCCCAGAAACTGGTGTGACTGACCCCCTTCCTATTTTAATCTGGCCATGCAGGGGAAGATGGACTACGGGGTGGTTTTTCTGTAACCTTGAAGACCCTGAGATCTCAACGGAAGTTTGTAGCTCTAATGAGAAAGCATAGGTGGGAGACTTCGGGAAAGGGGACGTTGAGTTCCGGAAAGCGGGGAGGACTGCTACTGGAAGTGGGCGCTGATGAAGAAGAAAGTACTATAGGTTTTCCATAGTAGCTGTGGAGTGAGTGAACTGTAAGAATAAATCAGGGCTCATTGGAGGCTGGCTGAGAACAGACCGGGATGTGCAGGCGATTGCAGGCGGCAGGGTTTGCAGGGTGGTGTTGTTAGTCGGTTGAGGGGCCGTGGGGGCTGGGGTTCAGTGAGCCTCCTCTTGGGGTACAG
Seq C2 exon
AACTTCACTGCCTCGGGAGAGGCAGAGGCGAGGCGCTGCGCGCGGCGAGAGGAGCTACTGGCTCGCGGGTGCCCCGCGCAGGAGCTAGAGGAGCCGAGAGGCCGCCAGGAGGTGCTGCAGGACAAGCCGCTCAGCCAGGGAGATCGCGGCGAGGGGGCCACCCAGCTGGCCCCGCAGCGGATCCGCGTCACGCTGCGACCAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSMUSG00000001281:ENSMUST00000001327:2
Average complexity
IR
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion (1st CDS intron)
No structure available
Features
Disorder rate (Iupred):
C1=0.178 A=NA C2=0.495
Domain overlap (PFAM):
C1:
PF0143720=PSI=PU(57.5=33.8),PF0036213=Integrin_beta=PU(50.0=25.0)
A:
NA
C2:
PF0143720=PSI=PD(64.8=67.6),PF0036213=Integrin_beta=FE(19.8=100)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
No suggested primer sequences
R:
No suggested primer sequences
Band lengths:
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Pre-implantation embryo development
- Ribosome-engaged transcriptomes of neuronal types
- Neural differentiation time course
- Muscular differentiation time course
- Spermatogenesis cell types
- Reprogramming of fibroblasts to iPSCs
- Hematopoietic precursors and cell types