MmuINT0088125 @ mm10
Intron Retention
Gene
ENSMUSG00000109764 | Klkb1
Description
kallikrein B, plasma 1 [Source:MGI Symbol;Acc:MGI:102849]
Coordinates
chr8:45286926-45289182:-
Coord C1 exon
chr8:45289020-45289182
Coord A exon
chr8:45287033-45289019
Coord C2 exon
chr8:45286926-45287032
Length
1987 bp
Sequences
Splice sites
5' ss Seq
ACGGTAAGA
5' ss Score
10.65
3' ss Seq
TGTGTTTTTTTAAAAAACAGGTT
3' ss Score
7.11
Exon sequences
Seq C1 exon
GGTGTATGACTCAACTGTATAAAAATACCTTCTTCAGAGGTGGGGATCTAGCTGCCATCTACACCCCAGATGCCCAGTACTGTCAGAAGATGTGCACTTTTCACCCCAGGTGCCTGCTGTTCAGCTTTCTCGCCGTGACTCCACCCAAAGAGACAAATAAACG
Seq A exon
GTAAGATGTGATGGTTTGTCATTGCCAGGTTAGATGTTACTTAAACTGCTTCCAGTTATATGCCAAAATAGTGCCATGTTTCTCAGAGTGTTCAAAGACTCTTTGCATCAGAAGCTCCTAGGCTGGGTCTTTTCAATGCAGACCCAAAGTACTGAACCCAGAGACAGACTCTAAACAGCCACAACACTTGTTCACAGTGATAGGAGGTAGTGATGCTACAGCCAAGGCCTGAAGACAGAGCATGTGACAAGAAAGGGTCCTTCCTCACACTGCAATACTTAGCCTTTTTTCACTTTCAACATGTTATTCTGTCCCCACATGTACATCTGTTATGTATATAAATGTTATTAGCTGGGTTATGCATATGAGGGAGAACCTGAGGGTTTTTTTTCTTTCTGAGATTATATGGCTTCCCTTAATATTAAAAATACTAAGTCCATCCATTTTCCTACAATTTTTGTGATTTCATTTCTCTTCAGCGCATAATAGCATTGCATTACATATTTTCTGTTTTATTCATTTGTGTATTAATTAATTTATTATAAATGCTGCAAATAAAACAATCACAGAACCAAATTAACCAGACTCAGAGACTGTGCAACTCAGTGAACTTCTATCCAGTTACAGTAATTGTTTGAAAAGGAAGCCAGGGAATGTCACAATGCACTTGATACTTTCACTATCAAATTTATATTTTAATCATATATATTGCTTTCTAATAAATGGTGACAATTTCACCTGCATAGAGAAATATATTTAATTGCTTTACTAGCTACCATATTTATAGGGAGCAAAGTTGAGAAAGTATAAGCCAGGAATTTTGTTGATAATAAATTTGAGACCCAGTAGGCAAGTCTCAATAGTGCCTGCAGTGGACCAGTTTACACTTTTAGAATATGCATTTTCTCTCTCTCTCTCTCTCTCCCTCTCTCTCTCTCCCTCTCTCTCTCTCCCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTATGTGTGTGTGTTTTATTAGGTGGTAATTTTGGCAAGAACAATTATTAAAAATATATTTGGAAATTTTACCTTAATTTTCTTTCATTTGATCAAGAGCCAAATGTAAATTTTTGCTTCTTTTTCCATACACATAACTTTCATCTTCAACTATGTGAATTTAAGAATTAGAATTTTAAAACTCATTCTCTGATCCCTACATGCTAATCTGTACCAAAAAAAACCCAAACAAACAAACAAACAAACAAAAAAACCCAGACCATATGTGAGATTTACATTTTTAAAAAAATTGAACCAGGTTCTAAGATTCTTATAAATAGCAACGTTAACATAGCGTTGATATTGAAGACAGAAAAAGCCTCCCATTACATGGACACTACCGGGAATCAATACACCAGATGAACATCACATGCAGACCTAACTCATAGCTGAGTCAGTTTTTTTAAAAGTAAATTAAAATCTTTATAACAATAATCACCATTTTAGAAAATGTGGATGTTTCAGACAGGAGAATCGTAAGTTTAAAGTCAGCTTGTGTAAGTTAACAAGATCCTTTGTCAAAGCAAACTAAGTAAAAGCTTGGGGTGGCATGGGGGGAGGAAAAGGCTGGTGATAATTATTAGGATTTGATTAGCATATTTGAAGCCCAGGCTCTCCTCCTCAGTACCACATAAACTAAGAACAAAACCAATGATCTTTTGGAAAGAGGAGCCAGCGACGTTCAGAATGAGAAAAGAATCATCAACCCTTCAGTGTGGTTGGCTCTCCGCACTTGCAGCGTAAACAGTAAGAAAAACAACGCTATAGAGAGCATGGACTTGTCGCAAGAACGTTCTCTTCAGCAAGTGACAAGGCCATGTTATTAGTTTCCTGACCCTGGGCTTTATTTATTAACATGTACAAAATACTGCATCATTTCTTAATGTGTGTTTGTTCAATTCCGCTTTTAAAATGTGTTTTTTTAAAAAACAG
Seq C2 exon
GTTTGGTTGCTTCATGAAAGAGAGCATTACAGGGACTTTGCCAAGAATACACCGGACAGGGGCCATTTCTGGTCATTCTTTAAAGCAGTGTGGCCATCAAATAAGTG
VastDB Features
Vast-tools module Information
Secondary ID
ENSMUSG00000109764:ENSMUST00000026907:3
Average complexity
IR
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=NA C2=0.000
Domain overlap (PFAM):
C1:
PF0002421=PAN_1=FE(62.8=100)
A:
NA
C2:
PF0002421=PAN_1=PD(34.9=81.1)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Zebrafish
(danRer10)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
ATACCTTCTTCAGAGGTGGGGA
R:
CACTTATTTGATGGCCACACTGC
Band lengths:
246-2233
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Pre-implantation embryo development
- Ribosome-engaged transcriptomes of neuronal types
- Neural differentiation time course
- Muscular differentiation time course
- Spermatogenesis cell types
- Reprogramming of fibroblasts to iPSCs
- Hematopoietic precursors and cell types