MmuINT0092576 @ mm10
Intron Retention
Gene
ENSMUSG00000027070 | Lrp2
Description
low density lipoprotein receptor-related protein 2 [Source:MGI Symbol;Acc:MGI:95794]
Coordinates
chr2:69523921-69525330:-
Coord C1 exon
chr2:69525161-69525330
Coord A exon
chr2:69524145-69525160
Coord C2 exon
chr2:69523921-69524144
Length
1016 bp
Sequences
Splice sites
5' ss Seq
AAGGTAACT
5' ss Score
9.01
3' ss Seq
AATTGTGTCATTTCTTTCAGGTT
3' ss Score
10.8
Exon sequences
Seq C1 exon
TCAGTGCGGCCTCCATTATCTTCTCTAATGGTCGGGATTTGCTAGTTGGAGATCTTCATGGAAGAAACTTCCGGATTCTAGCAGAGTCTAAGAACCGTGGAATAGTTATGGGAGTGGATTTTCACTATCAGAAGCACAGAGTTTTTTGGACAGACCCCATGCAGGCGAAG
Seq A exon
GTAACTAGAAAATTCAAGGGCATAGCTTATGGGCCAAATGGAACCTAAAGCACAAAGTGTTGATAGCTTTTCATTTTGGGGGGAGGAGAGGGGAAAATTCCTTTGTTTTCTGACAAGAATAGCCCTTGAGATATTTTATGTTAGTCAGCGTTTTTTTCCCATGCTATACTATTACATGTGACCTGTGAGACAAAGACAGCTATTATTTGGATTAGCCTTGAGCAACTTTTAATTTTATTCATAAAGGAGTCCAAAAGCCTAATGAAAAGAAATCATAGACCTTTCAGAGCTAGATAGATATTTAGTCGCCATTTTGGAAACTTGATCATTTAAAATATAAAAATACTCTTCTTACTTGCATGATAAAAATCAGATTTTTTTTTAAACCTTCATCTTGCACATGGAATTGTAATTGAAGGTTGGGCAAAAAAATTGTTTTTTTTTTTTTTTTTTTAATGTGATGCTCAAAATCTCATTGCATTGTTTTACTTAGAAAGTAAGATTGATTTTAGTTAGAAATTTGACTATAATATAGATTCAGATTCATGAAACATACATTTTAGAAACTGCTAAAAAGTCATGGAATTTTGTTTATTCTTGCTGCATTTCTTTTAATGTGAAACCAAGTGTGTCTTTAAAACATTCTAATTAAGGCTAACACACAAAGTTGAATTTTGATCATTAGCAATTCTTATTTGAATAAAACTAAAAATCAAAACAAAATACTATCATCTTTATCAAAACAAAACAAAACAAAACAAAACAAAACAAAACAAAATAAAACACTCTACAAAACTCGACCATGTATTTACCTTATATATACTGAACAGGATCCATTTTCTTCTGGTAGCATTGTAGGGTTGAGGTAGTACTTTCTATCTATCCATCCATCTGTCTGTCTGTCTGTTTATCTATTTATGTATCTACTATAAGTAGATACATATAGATAAAAAATATAGGAAAACAGGGTTCATGCTCAGGTTTAGGAAGTATAACAATTGTGTCATTTCTTTCAG
Seq C2 exon
GTTTTTTCCACTGACATTAATGGCTTAAATACCCAAGAAATTCTTAATGTTTCTATTGATGCTCCAGAGAATCTGGCTGTGGATTGGATTAATAATAAACTTTATCTGGTAGAGACAAGAGTCAACCGCATTGATGTGGTCAACTTGGAGGGAAATCAGCGTGTTACTCTCATAACTGAAAACTTGGGGCATCCTAGAGGAATTGCCCTTGATCCAACTGTGGG
VastDB Features
Vast-tools module Information
Secondary ID
ENSMUSG00000027070:ENSMUST00000080953:11
Average complexity
IR
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=NA C2=0.000
Domain overlap (PFAM):
C1:
PF0005812=Ldl_recept_b=PU(26.8=19.3)
A:
NA
C2:
PF0005812=Ldl_recept_b=PD(68.3=37.3),PF0005812=Ldl_recept_b=WD(100=54.7),PF0005812=Ldl_recept_b=PU(0.1=0.0)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
TGGTCGGGATTTGCTAGTTGG
R:
GCAATTCCTCTAGGATGCCCC
Band lengths:
348-1364
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Pre-implantation embryo development
- Ribosome-engaged transcriptomes of neuronal types
- Neural differentiation time course
- Muscular differentiation time course
- Spermatogenesis cell types
- Reprogramming of fibroblasts to iPSCs
- Hematopoietic precursors and cell types