Special

MmuINT0096300 @ mm9

Intron Retention

Gene
ENSMUSG00000027763 | Mbnl1
Description
muscleblind-like 1 (Drosophila) [Source:MGI Symbol;Acc:MGI:1928482]
Coordinates
chr3:60426068-60429120:+
Coord C1 exon
chr3:60426068-60426162
Coord A exon
chr3:60426163-60429045
Coord C2 exon
chr3:60429046-60429120
Length
2883 bp
Sequences
Splice sites
5' ss Seq
CAGGTTTGC
5' ss Score
4.86
3' ss Seq
AACGATTTTTTATTTGCTAGATA
3' ss Score
5.91
Exon sequences
Seq C1 exon
TTCCCATGGTGCACGGTGCTACGCCAGCCACTGTGTCCGCAGCAACAACATCTGCCACAAGTGTTCCCTTCGCTGCAACAGCCACAGCCAACCAG
Seq A exon
GTTTGCTAATTTACAGCTTTGTTTCTTAAAACCAACTCTTAATAGGACCCAGTCCAACCGCTTTAACATTAGCACATGGAACTCCCATTCTGCTCAGTGGGAGCTGTGTATGGGAGAGCTGTAGAGGGTGCTTTCACGAGCATGGGTTTTCAAAGATACCTCTTGTTGGCCTACACATTCCCTTTATGACAATAGCAGATTCCTTTTATGCCATTTATAAGTGCTCCAAAGTTTTCGCAGCTCTGTTTCTGAAGCTACTAAACTGATATTTACACAAGCAATTCTCATTTTTCTTAACTAGTCTGTACTTTGGCCAACCAAAATAAAAGCAATTATGAGGTTATTCTTAAAGCATCTGATATATAGTTTTTTAGTTCTTTCCTAAATTTTTAATAAAAAAGAAAAAATATAAATGCATTTCTATGCCACAAATGACCACTCTTATAAATGGTTGTTTTTTACAATATAAATTTTGATAAGCAAATTGCTTACTAAAATTAATTACTTTTATATGCAACATCTTTCAGCTATGATTCTTGCTATTTTAAATGAAAAATGAAATTAAAGGATGTCATTTCTACAGTTAACCTGAATAAATGTTGGAGGTATTGAAAGTAAAAGAAATCATGTATGATAAATAACAGTTATTCTGTGCTCAGTTAAAATATGGAGGAAAGAAACATGCAGAATTCTTTTAAGCAGATAGGACCTACTTAAATTTAAATGATATGGACAAGAATGGGCTAGTTAAAGCAAAATGGTCATTTAAGGTATTTAAATTTTAGAATGCCATGACTCCCACCAGCATTTTCTGTACAAAAATATTTTCTAGCTCTGAACTAATTAAGCTCACATTTTAGAAGTAAATCTGCCCTTGAATATTCAGATATGTATGTTAGGATAGCACAGTTCACTAGGGTTGGTGATGTATGAAAGGCACTAAAGCAGGTTACACATGGCCCACTGACTGAGGTTAGACGGGGCCTCGGGAGAGTAAGGAGAAGCCTTGTCAGATGGACTCAGTGCAGCGCCCCTGGGACAAGTACACCAACTGTTATTACAATGAGGAACAGACACCTTCTCGTTTTTTTCAATATATCATCTTTTGATGAATTTTCAGCTATTAATATAGTCATTAATAAGTTTCAAGAATATAGTTCCAAATGGATTTAATTTTAAGTTCCAGACAAGCCTTAAATATTTCTTTGAAAAACATAATTAGTTTTTCAAACTTATCAAAATAGCCTTGGATTTATGCAAACACGTAAGACTCATCTATAAGGACAAGAGCGTGTGCATATGTGGCATGATAGTTGTTTTAAGTGGATTTGGTGGAGACAATTTATGGTGCAGGTAAACGATGCTGGAGGCTCGTGTGCATACCATATATGACTATAGAATTGCTGGTGTAAGCACAACTATAGCAAAGCAAATTCAACATGCCCTTGGCCACTTGGGTTGTAAGGGACACTTCTTGCATTGTGCTGTGACCATTTCATGCATAATTCTTGGGTCTTCATACTATTACTATTTTACAACCAAAGAAAAGGGAATGGATATATATATATACACACATATATTATATCTACATATACATACATATGTATATGCCTACAGTACATTAGCAATGCTGGAAATAGCTCATGCCACAAAATTCAGCCTGCATGCATGCAGAAGTTTATAGCTGGCCCTTCATCTGCATTGAGTGGTGTTGAAGGTCCTTGGTATGTTTCAACAGCCCCATCCTTGATGCTTCTACACTGTTGGGTGCAACATCCTGCCTGCAGCAGCAGGAACAATGGTATGAGAAGCTTCGTTATGCTCGGAGCACAGTTTTGTGCCATTTGCCATTGCTGTAAAACTGTGTAAAATGTCAGCGAAGAAACAACGGTTAAAAGGCACATAGTGAAACATCGTTTTTAGTAGATGGAGATAATCGAGGATATTTAAATTAAAACAATAGCAAAAACCTTCAGGAGCGTGAGTTCATTGCTACCCCAACAGACTTTCTGAAATGGAGTTAGTGCATTGGACAGAATAAGTTGAAATGCACTCACCAGTTGCTTTGCTTAGGGCCACACAACCAAAAACAAGTCAGTGTTGTTAGAACCAGTGTCCTCAGGCCTCGGCTACACTCAAGCTGTGGGGCTACCTCTCCCACTTACCAGTCTTTAATTGGAGCTTGAAAGAGAATCAAATCACAAATCCAATTTCCTGGCTCTTGTATATTGGAAAAAGTAACCTCTGTACCAGTTTCTTTTGTGTTTTTTTCTCCAGCTGTCTGATACTTACTTGCCTATTTAAATGCAGTGAAATGTGTAGTAGAAATGCTGAAGTCTGCTCAGGAGAAAACCTATTCTCTTTCCAAGTTATTTTTTAATTACTATTTTGTAATGTTTTCATTTGAGACAAAAGTTAAACACTTTGATCTGAATGAAATGTTAGAAACTTGCTTTCACAAAATTAGCCAAGGCATTTTTTACTCTTGATTTCAGTATTATTGCTATTATTATTATTATTATTATTATTATTATTATTATTATTATTATTAAGGGGTGTGTGCGTGCGCGCGCGTGTGTGTAGGCCAACAAAAAGGGCTTCTTTTAACAAAGGCTCTGCATGCAGTTTTGATAGCTGTACTTCTATTCCTTCCTAAGTACTGGTAACATTTGGAGACTAGTATTTAACATGGAGATTACAAGCAGTGATTTGCTTCTATGGCATTTACATTTTCGTTAACTTAATGTCATGTTGACCAGATGAGGGCTGTCACTTCACAGCTGAATCTCACTGTTTATATAAGTTTAATATTAAGATGTTCTCACCTCTTGGTGGTTGGCTTGCTTGCATGGATCATTCATTAAACGATTTTTTATTTGCTAG
Seq C2 exon
ATACCCATAATATCTGCCGAACATCTGACTAGCCACAAGTATGTTACCCAGATGTAGAGCTGTCGTCACAAAACA
VastDB Features
Vast-tools module Information
Secondary ID
ENSMUSG00000027763-Mbnl1:NM_020007:8
Average complexity
IR-S
Mappability confidence:
NA
Protein Impact





	

	
ORF disruption upon sequence inclusion





No structure available

		

			
Features


			

				
Disorder rate (disopred):
  C1=0.969 A=NA C2=0.354
 
                        

				
Domain overlap (PFAM):

					





						

							
C1:
NO

							
A:
NA

							
C2:
NO

						

					

				








    
Main Inclusion Isoform:
NA





     
                   









    
Main Skipping Isoform:
ENSMUSP00000029327f2177A





     
      









    
Other Inclusion Isoforms:
NA
          









    
Other Skipping Isoforms:
ENSMUSP00000029327, ENSMUSP00000029327f2175A, ENSMUSP00000096686, ENSMUSP00000126717, ENSMUSP00000127184
  



Associated events






Other assemblies


mm10




Conservation


Human
(hg38)
chr3:152456362-152459270 
LOW PSI
HsaINT0100440
(MBNL1)
Human
(hg19)
chr3:152174151-152177059 
LOW PSI
HsaINT0100440
(MBNL1)
Rat
(rn6)
chr2:150864897-150867718 
ALTERNATIVE
RnoINT0090146
(Mbnl1)
Cow
(bosTau6)
chr1:116241682-116244665 
LOW PSI
BtaINT0090404
(MBNL1)
Chicken
(galGal4)
chr9:22849028-22851959 
ALTERNATIVE
GgaINT0031674
(MBNL1)
Chicken
(galGal3)
chr9:24953747-24956678 
ALTERNATIVE
GgaINT0031674
(MBNL1_CHICK)
Zebrafish
(danRer10)
chr2:47971712-47973053 
LOW PSI
DreINT0093796
(mbnl1)
Fruitfly
(dm6)
No conservation detected




Primers PCR

	

		

			
Suggestions for RT-PCR validation

			

				
F: 
No suggested primer sequences

				
R: 
No suggested primer sequences

				
Band lengths: 

			

		

	





	
Functional annotations
(Submit an annotation)

	


There are 0 annotated functions for this event 


		










GENOMIC CONTEXT[edit]












INCLUSION PATTERN[edit]






SPECIAL DATASETS
  • Pre-implantation embryo development
  • Muscular differentiation time course
  • Spermatogenesis cell types
  • Reprogramming of fibroblasts to iPSCs
  • Hematopoietic precursors and cell types






Retrieved from "https://vastdb.crg.eu/wiki/Special:VastDB"